Survey
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
Download Family - BioMed Central
Document related concepts
no text concepts found
Transcript
Table A2: Genes included in the IPA networks at 2 hrs Name Description Genbank Ntwk ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 AL359600 ACVR1B activin A receptor, type IB AL117643 2 ADCY1 adenylate cyclase 1 (brain) -- 4 ADCY2 adenylate cyclase 2 (brain) -- 4 AFM afamin v-akt murine thymoma viral oncogene homolog 1 NM_001133 2 -- 4 apolipoprotein L, 1 amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) arginase, liver argininosuccinate synthetase bromodomain adjacent to zinc finger domain, 1A -BCL2/adenovirus E1B 19kDa interacting protein 3 AF323540 AKT1 Location Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Extracellular Space Family transporter kinase enzyme enzyme transporter ---- 2 3 3 Cytoplasm Extracellular Space Plasma Membrane Cytoplasm Cytoplasm NM_013448 AF070674 9 1 Nucleus Cytoplasm other other -- 3 other carbonic anhydrase VI calcium channel, voltage-dependent, L type, alpha 1B subunit NM_001215 7 -- 4 NM_001753 4 CBX8 caveolin 1, caveolae protein, 22kDa chromobox homolog 8 (Pc class homolog, Drosophila) Cytoplasm Extracellular Space Plasma Membrane Plasma Membrane -- 5 other CCL2 chemokine (C-C motif) ligand 2 NM_002982 1 CCL4 chemokine (C-C motif) ligand 4 NM_002984 1, 2 CCL6 -- -- 2 CCL20 chemokine (C-C motif) ligand 20 NM_004591 1 CCL3L1 chemokine (C-C motif) ligand 3-like 1 D90145 4 Nucleus Extracellular Space Extracellular Space Extracellular Space Extracellular Space Extracellular Space CCR3 chemokine (C-C motif) receptor 3 -- 4 Plasma Membrane CCR5 chemokine (C-C motif) receptor 5 -- 4 CD24 -- 2 NM_001816 1 CEBPD CHRAC1 CD24 molecule carcinoembryonic antigen-related cell adhesion molecule 8 CCAAT/enhancer binding protein (C/EBP), delta chromatin accessibility complex 1 NM_005195 -- 1 9 CLU COP (LOC1147 clusterin caspase-1 dominant-negative inhibitor pseudo-ICE -NM_052889 APOL1 APP ARG1 ASS BAZ1A BIRC3 BNIP3 CA6 CACNA1B CAV1 CEACAM8 Plasma Membrane Plasma Membrane Plasma Membrane kinase transporter other enzyme enzyme enzyme ion channel other cytokine cytokine cytokine cytokine cytokine G-protein coupled receptor G-protein coupled receptor other other other other 2 Nucleus Nucleus Extracellular Space 1 Unknown other other 69) CR2 complement component (3d/Epstein Barr virus) receptor 2 -- 4 Plasma Membrane Extracellular Space Extracellular Space transmembra ne receptor CSF3 colony stimulating factor 3 (granulocyte) NM_000759 1 CTGF NM_001901 2 CTSD connective tissue growth factor cathepsin D (lysosomal aspartyl peptidase) -- 2 peptidase 1 Cytoplasm Extracellular Space Extracellular Space Extracellular Space Extracellular Space CX3CL1 chemokine (C-X3-C motif) ligand 1 -- 2, 4 CXCL2 chemokine (C-X-C motif) ligand 2 NM_002089 1 CXCL10 chemokine (C-X-C motif) ligand 10 NM_001565 1 CXCL11 chemokine (C-X-C motif) ligand 11 NM_005409 DDIT3 DNA-damage-inducible transcript 3 -- 7 Nucleus DSCR1 DUSP6 Down syndrome critical region gene 1 dual specificity phosphatase 6 -NM_001946 2 2 Nucleus Cytoplasm E2F1 E2F transcription factor 1 -- 3 Nucleus -- 4 -- 2 -- 3 -- 2 ERBB2 endothelial differentiation, sphingolipid Gprotein-coupled receptor, 1 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) F2 coagulation factor II (thrombin) EDG1 EPB41 Plasma Membrane Plasma Membrane Plasma Membrane Extracellular Space cytokine growth factor cytokine cytokine cytokine cytokine transcription regulator transcription regulator phosphatase transcription regulator G-protein coupled receptor other kinase peptidase FABP5 coagulation factor III (thromboplastin, tissue factor) fatty acid binding protein 5 (psoriasisassociated) FAS Fas (TNF receptor superfamily, member 6) -- 3 FGG fibrinogen gamma chain -- 3 FLT3LG fms-related tyrosine kinase 3 ligand -- 4 Plasma Membrane Extracellular Space Extracellular Space FSHR follicle stimulating hormone receptor growth arrest and DNA-damage-inducible, beta guanylate binding protein 1, interferoninducible, 67kDa guanylate binding protein 2, interferoninducible grancalcin, EF-hand calcium binding protein -glutamate-ammonia ligase (glutamine synthetase) guanine nucleotide binding protein (G -- 2 Plasma Membrane cytokine G-protein coupled receptor NM_015675 1 Cytoplasm other NM_002053 1 Cytoplasm enzyme NM_004120 1 Cytoplasm enzyme NM_012198 -- 8 3 Cytoplasm Unknown other other AL161952 -- 2 4 Cytoplasm Plasma enzyme enzyme F3 GADD45B GBP1 GBP2 GCA GLP109 GLUL GNAI1 NM_001993 1, 2 Plasma Membrane transmembra ne receptor NM_001444 1 Cytoplasm transporter transmembra ne receptor other HIF1A protein), alpha inhibiting activity polypeptide 1 guanine nucleotide binding protein (G protein), beta polypeptide 1 guanine nucleotide binding protein (G protein), beta polypeptide 2 guanine nucleotide binding protein (G protein), beta polypeptide 3 guanine nucleotide binding protein (G protein), beta 5 guanine nucleotide binding protein (G protein), gamma 3 guanine nucleotide binding protein (G protein), gamma 4 guanine nucleotide binding protein (G protein), gamma 5 guanine nucleotide binding protein (G protein), gamma 7 guanine nucleotide binding protein (G protein), gamma 10 guanine nucleotide binding protein (G protein), gamma 11 guanine nucleotide binding protein (G protein), gamma 12 guanine nucleotide binding protein (G protein), gamma 13 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) HP HRASLS3 HSPB8 haptoglobin HRAS-like suppressor 3 heat shock 22kDa protein 8 GNB1 GNB2 GNB3 GNB5 GNG3 GNG4 GNG5 GNG7 GNG10 GNG11 GNG12 GNG13 Membrane 4 -- 4 NM_002075 4 -- 4 -- 4 -- 4 -- 4 -- 4 -- 4 -- 4 -- 4 -- 4 NM_001530 3 AK055872 -NM_014365 1 3 2 Nucleus Extracellular Space Nucleus Unknown NM_000201 1 Plasma Membrane transmembra ne receptor NM_002165 2 Nucleus Extracellular Space Extracellular Space Extracellular Space Extracellular Space other Plasma Membrane Extracellular Space Extracellular Space transmembra ne receptor ID1 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor inhibitor of DNA binding 1, dominant negative helix-loop-helix protein IFNG interferon, gamma -- 3 IFNK interferon, kappa -- 3 IL4 interleukin 4 -- 4 IL6 interleukin 6 (interferon, beta 2) NM_000600 1 IL15RA interleukin 15 receptor, alpha NM_002189 1 IL1B interleukin 1, beta NM_000576 1 IL1RN interleukin 1 receptor antagonist X52015 1 IRF1 ITPKC KIAA0101 KIAA0186 KIAA0963 KIAA1276 interferon regulatory factor 1 inositol 1,4,5-trisphosphate 3-kinase C KIAA0101 GINS complex subunit 1 (Psf1 homolog) KIAA0963 KIAA1276 protein NM_002198 D38169 --NM_014963 AB033102 3 KITLG Klrb1c KIT ligand killer cell lectin-like receptor subfamily B --- 2 3 ICAM1 Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane Plasma Membrane -- 3 3 1 3 Nucleus Unknown Nucleus Unknown Unknown Unknown Extracellular Space Plasma enzyme enzyme enzyme enzyme enzyme enzyme enzyme enzyme enzyme enzyme enzyme enzyme transcription regulator peptidase other kinase cytokine cytokine cytokine cytokine cytokine cytokine transcription regulator kinase other other other other growth factor other KPNA2 LCN2 LCP1 LYN MAPK3 MARCKS MATK MLLT3 MME MYC MYH9 NDRG2 NFKBIA NFKBIE NFYB NP NUP88 NUP214 OAS1 OAS2 member 1C karyopherin alpha 2 (RAG cohort 1, importin alpha 1) Membrane NM_002266 2 Nucleus Extracellular Space Cytoplasm transporter lipocalin 2 (oncogene 24p3) lymphocyte cytosolic protein 1 (L-plastin) v-yes-1 Yamaguchi sarcoma viral related oncogene homolog mitogen-activated protein kinase 3 myristoylated alanine-rich protein kinase C substrate megakaryocyte-associated tyrosine kinase myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) v-myc myelocytomatosis viral oncogene homolog (avian) myosin, heavy polypeptide 9, non-muscle NDRG family member 2 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon NM_005564 -- 1 8 NM_002350 -- 3 2 kinase kinase 2 3 Cytoplasm Cytoplasm Plasma Membrane Cytoplasm NM_002356 -- NM_004529 5 Nucleus other -- 2 Plasma Membrane --NM_016250 2 2 4 Nucleus Cytoplasm Cytoplasm NM_020529 1 Cytoplasm NM_004556 1 Nucleus -NM_000270 NM_002532 -- 3 4 6 6 Nucleus Nucleus Nucleus Nucleus other transcription regulator transcription regulator enzyme transporter transporter nuclear transcription factor Y, beta nucleoside phosphorylase nucleoporin 88kDa nucleoporin 214kDa 2',5'-oligoadenylate synthetase 1, 40/46kDa 2'-5'-oligoadenylate synthetase 2, 69/71kDa -- 3 Cytoplasm enzyme -- 3 Cytoplasm -- 2 Plasma Membrane enzyme G-protein coupled receptor -- 3 Cytoplasm enzyme -- 2 Extracellular Space growth factor AF334710 3 Cytoplasm kinase -- 3 Cytoplasm other ---- 4 4 4 Cytoplasm Cytoplasm Cytoplasm kinase enzyme enzyme -NM_021129 9 3 Nucleus Cytoplasm Nucleus Cytoplasm Extracellular Space enzyme enzyme liganddependent nuclear receptor enzyme POLE3 PP purinergic receptor P2Y, G-protein coupled, 2 phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) pyruvate dehydrogenase kinase, isozyme 4 pleckstrin homology-like domain, family A, member 1 phosphoinositide-3-kinase, catalytic, gamma polypeptide phospholipase C, beta 2 phospholipase C, epsilon 1 polymerase (DNA directed), epsilon 3 (p17 subunit) pyrophosphatase (inorganic) 1 PPARA PPIA peroxisome proliferative activated receptor, alpha peptidylprolyl isomerase A (cyclophilin A) --- 3 4 PRG1 proteoglycan 1, secretory granule NM_002727 2 P2RY2 PDE4A PDGFB PDK4 PHLDA1 PIK3CG PLCB2 PLCE1 transporter other other kinase peptidase transcription regulator other other other S100A9 phosphoribosyl pyrophosphate synthetase-associated protein 1 HtrA serine peptidase 2 pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1) RAB3C, member RAS oncogene family regulator of G-protein signalling 3 receptor-interacting serine-threonine kinase 2 S100 calcium binding protein A8 (calgranulin A) S100 calcium binding protein A9 (calgranulin B) SDC4 syndecan 4 (amphiglycan, ryudocan) SERPINA 3 serpin peptidase inhibitor, clade A (alpha1 antiproteinase, antitrypsin), member 3 solute carrier family 39 (zinc transporter), member 8 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) superoxide dismutase 2, mitochondrial PRPSAP1 PRSS25 other peptidase 1 Unknown Cytoplasm Extracellular Space Cytoplasm Nucleus Plasma Membrane NM_002964 1 Cytoplasm other NM_002965 1 other NM_002999 2 Cytoplasm Plasma Membrane NM_001085 3 Extracellular Space other NM_022154 3 Unknown transporter -- 9 Nucleus transcription regulator -- 9 Nucleus transcription regulator -NM_000636 2 1 enzyme enzyme SPARC-like 1 (mast9, hevin) sorcin tissue factor pathway inhibitor (lipoproteinassociated coagulation inhibitor) NM_004684 -- 3 8 -- 2 Cytoplasm Cytoplasm Extracellular Space Cytoplasm Extracellular Space NM_000361 1 transmembra ne receptor NM_006291 1 Plasma Membrane Extracellular Space TNFAIP3 TNIP1 thrombomodulin tumor necrosis factor, alpha-induced protein 2 tumor necrosis factor, alpha-induced protein 3 TNFAIP3 interacting protein 1 NM_006290 NM_006058 1 1 Nucleus Nucleus TSC22D3 TXNIP TXNRD1 TSC22 domain family, member 3 thioredoxin interacting protein thioredoxin reductase 1 AB025432 -NM_003330 2 2 3 VCAM1 WARS vascular cell adhesion molecule 1 tryptophanyl-tRNA synthetase NM_001078 NM_004184 1 3 Nucleus Cytoplasm Cytoplasm Plasma Membrane Cytoplasm other other transcription regulator other enzyme YY1 YY1 transcription factor zinc finger protein 36, C3H type, homolog (mouse) AK026497 4 Nucleus NM_003407 3 Nucleus PTN RAB3C RGS3 RIPK2 S100A8 SLC39A8 SMARCA1 SMARCA5 SMPD2 SOD2 SPARCL1 SRI TFPI THBD TNFAIP2 ZFP36 NM_002766 -- 3 4 ---- 2 3 4 NM_003821 growth factor enzyme other kinase other other transporter other other other enzyme transcription regulator transcription regulator
Related documents