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Online Appendix for the following August 5, 2008 JACC article
TITLE: Functional Status After Operation for Ebstein Anomaly: The Mayo Clinic Experience
AUTHORS: Morgan L. Brown, MD, Joseph A. Dearani, MD, FACC, Gordon K. Danielson,
MD, FACC, Frank Cetta, MD, FACC, Heidi M. Connolly, MD, FACC, Carole A. Warnes, MD,
FACC, Zhuo Li, MS, David O. Hodge, MS, David J. Driscoll, MD, FACC
APPENDIX
Independent Variables of Interest
Demographics and Lab Data
Age at Operation
Age at Diagnosis by History
Patient gender
Surgeon (1 and 2)
Preoperative cardiothoracic ratio on chest x-ray
Preoperative oxygen saturation
Preoperative hemoglobin
Preoperative hematocrit
Echocardiography
Preoperative right ventricular size
Preoperative right ventricular systolic function
Preoperative tricuspid valve regurgitation severity
Preoperative left ventricular systolic function
Anatomic severity of Ebstein’s anomaly
TV repairable – yes, no, equivocal
Mitral valve systolic regurgitation
Pulmonary valve stenosis
Architecture of pulmonary arteries-hypoplastic, stenotic, or normal
Postoperative right ventricular size
Postoperative right ventricular systolic function
Postoperative tricuspid valve regurgitation severity
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Postoperative left ventricular systolic function
Associated heart disease
Atrial septal defect or patent foramen ovale
Accessory conduction pathway
Pulmonary valve stenosis
Ventricular septal defect
Atrioventricular node reentry tachycardia
Bilateral superior venae cavae
Patent ductus arteriosus
Partial atrioventricular septal defect
Coronary artery disease on angiography
Anomalous pulmonary venous connection
Pericarditis
Hypertrophic obstructive cardiomyopathy
Absent coronary sinus
Mitral valve regurgitation requiring surgical intervention
Subvalvular pulmonary stenosis/RVOT obstruction
Pulmonary artery stenosis or hypoplasia
Pulmonary valve regurgitation
Miscellaneous associated cardiac defects – not included in any above
Previous CV procedure
Any prior cardiac procedure – including surgical procedures, pacemakers,
and catheter based interventions
Prior closure of atrial septal defect
Prior tricuspid valve repair
Prior tricuspid valve replacement
Prior systemic-to-pulmonary artery shunt
Prior cavo-pulmonary shunt
Prior permanent pacemaker
Prior ablation of accessory pathway – catheter based and surgical based
Prior closure of ventricular septal defect
Prior pulmonary valvotomy
Prior pulmonary valve replacement
Prior pulmonary artery banding
Prior coronary stenting or coronary artery bypass grafting
Prior repair of coarctation
Prior closure of patent ductus arteriosus
Prior enlargement of right ventricular outflow tract
Prior complete pericardiectomy
Prior left superior vena cava ligation
Surgical procedure
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Closure of atrial septal defect
Right reduction atrioplasty
Plication of atrialized right ventricle
Anterior right pericardiectomy
Tricuspid valve repair
Tricuspid valve replacement
Ablation of accessory pathway(s)
Right-sided Maze procedure
Closure of any shunt
Systemic to pulmonary shunt
Cavopulmonary shunt
Repair pulmonary valve stenosis
Closure of ventricular septal defect
Ablation of a-v node reentrant tachycardia
Fontan
Coronary stenting or CABG
Repair of coarctation
Repair partial atrioventricular septal defect
Systemic to pulmonary artery shunt
Coronary Artery Bypass Grafting
Repair of partial anomalous pulmonary veins
Permanent pacing wires
Miscellaneous arrhythmia procedure – ablation of right or left isthmus or left
sided maze
Mitral valve replacement or repair
Complete pericardiectomy
Pulmonary valve replacement
Myectomy
Enlargement of right ventricular outflow tract
Branch pulmonary artery enlargement
Electrophysiologic mapping
Closure of patent ductus arteriosus
Mechanical support and transplant
Miscellaneous operation not listed above
Early non-fatal complications (<30 days)
Third degree heart block - transient (<3 days)
Third degree heart block – permanent
Ventricular arrhythmia – premature ventricular contractions, ventricular
tachycardia or fibrillation
Wide complex tachycardia – ventricular tachycardia or fibrillation
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Junctional tachycardia
Atrial arrhythmia – atrial fibrillation, atrial flutter, premature atrial
contractions, supraventricular tachycardia
Miscellaneous arrhythmia not listed above
Myocardial Infarction
Cerebrovascular accident
Low cardiac output state – inotropes >3d
Intraaortic balloon pump inserted in the intensive care unit
Respiratory Insufficiency – ventilated >3d
Renal insufficiency – >3 mg/dL
Dialysis
Gastrointestinal bleed
Deep sternal wound infection
Extra-corporeal membrane oxygenation
Sepsis or endocarditis or pneumonia
Neurological complication – seizures or transient ischemic attack
Thrombus on tricuspid valve or in right atrium requiring anticoagulation
Post pericardial syndrome
Hematologic complication
Miscellaneous complication not otherwise specified
Early reoperation
Bleeding
Tamponade
Permanent pacemaker for 3rd degree heart block
Permanent pacemaker (miscellaneous reason)
Tracheostomy
Delayed sternal closure
Wound debridement
Tricuspid valve reoperation
LVAD,RVAD or mechanical support
Creation of shunt
Pericardiectomy
Closure of shunt
Emergent opening of chest in ICU
Miscellaneous early reoperation not listed above
Arrhythmia data
Past history of any arrhythmia (including palpitations and other arrhythmias)
Past history of a specific arrhythmia (excluding palpitations)
Cardiac arrest prior to operation (prior to entering the operating theater)
Accessory pathway on electrophysiologic (EP) study
AV nodal re-entry tachycardia on EP study
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Inducible ventricular tachycardia on EP study
Inducible ventricular fibrillation on EP study
Catheter ablation procedure on EP study
Patients in Sinus rhythm preoperatively on electrocardiogram (ECG)
Patients with preexcitation on preoperative ECG
Patients in sinus rhythm at dismissal on ECG
QRS duration on dismissal or follow-up ECG
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