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Molecular Genetics Study Guide 1. What were the contributions of the following scientists? a. Meischer b. Hershey and Chase c. Watson and Crick d. Wilkins and Franklin 2. Define DNA. 3. What are the 3 parts of a DNA nucleotide? 4. What are the 4 nitrogenous bases in DNA? 5. Which nitrogenous bases in DNA are purines? 6. Which nitrogenous bases in DNA are pyrimidines? 7. What are the base pairing rules in DNA? 8. What kind of bonds hold the phosphates and deoxyribose sugars together in DNA? 9. What kind of bonds hold the nitrogenous base pairs together in DNA? 10. What is DNA named for? 11. What do we call the copying of DNA? 12. What is the function of helicase? 13. What is the function of DNA polymerase? 14. If you are given the following sequence of DNA, what is its complement that would be constructed during replication? ATGGATTA 15. Define RNA. 16. What are the 3 parts of an RNA nucleotide? 17. What are the nitrogenous bases in RNA? 18. Which nitrogenous bases in RNA are purines? 19. Which nitrogenous bases in RNA are pyrmidines? 20. What is RNA named for? 21. What is the function of mRNA? 22. What is the structure of mRNA? 23. What is a codon? 24. What is the function of tRNA? 25. What is the structure of tRNA? 26. What is an anti-codon? 27. What is the function of rRNA? 28. What is the structure of rRNA? 29. What is transcription? 30. What is translation? 31. What is the function of RNA polymerase? 32. What kind of bond holds amino acids together in a protein? 33. What is another name for a protein? 34. Transcribe (mRNA), translate (amino acids) and determine the tRNA anti-codons related to the following DNA sequence. Use your codon chart for translating. DNA template-TAC CAT TTA 35. Review your notes, worksheets, etc in preparation for the test.