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How does the urinary system work? Your body takes nutrients from food and uses them to maintain all bodily functions including energy and self-repair. After your body has taken what it needs from the food, waste products are left behind in the blood and in the bowel. The urinary system works with the lungs, skin, and intestines—all of which also excrete wastes—to keep the chemicals and water in your body balanced. Adults eliminate about a quart and a half of urine each day. The amount depends on many factors, especially the amounts of fluid and food a person consumes and how much fluid is lost through sweat and breathing. Certain types of medications can also affect the amount of urine eliminated. Front view of urinary tract The urinary system removes a type of waste called urea from your blood. Urea is produced when foods containing protein, such as meat, poultry, and certain vegetables, are broken down in the body. Urea is carried in the bloodstream to the kidneys. The kidneys are bean-shaped organs about the size of your fists. They are near the middle of the back, just below the rib cage. The kidneys remove urea from the blood through tiny filtering units called nephrons. Each nephron consists of a ball formed of small blood capillaries, called a glomerulus, and a small tube called a renal tubule. Urea, together with water and other waste substances, forms the urine as it passes through the nephrons and down the renal tubules of the kidney. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The ureters are about 8 to 10 inches long. Muscles in the ureter walls constantly tighten and relax to force urine downward away from the kidneys. If urine is allowed to stand still, or back up, a kidney infection can develop. Small amounts of urine are emptied into the bladder from the ureters about every 10 to 15 seconds. The bladder is a hollow muscular organ shaped like a balloon. It sits in your pelvis and is held in place by ligaments attached to other organs and the pelvic bones. The bladder stores urine until you are ready to go to the bathroom to empty it. It swells into a round shape when it is full and gets smaller when empty. If the urinary system is healthy, the bladder can hold up to 16 ounces (2 cups) of urine comfortably for 2 to 5 hours. Circular muscles called sphincters help keep urine from leaking. The sphincter muscles close tightly like a rubber band around the opening of the bladder into the urethra, the tube that allows urine to pass outside the body. Nerves in the bladder tell you when it is time to urinate (empty your bladder). As the bladder first fills with urine, you may notice a feeling that you need to urinate. The sensation to urinate becomes stronger as the bladder continues to fill and reaches its limit. At that point, nerves from the bladder send a message to the brain that the bladder is full, and your urge to empty your bladder intensifies. When you urinate, the brain signals the bladder muscles to tighten, squeezing urine out of the bladder. At the same time, the brain signals the sphincter muscles to relax. As these muscles relax, urine exits the bladder through the urethra. When all the signals occur in the correct order, normal urination occurs. Urinary System, system of organs that produces and excretes urine from the body. Urine is a transparent yellow fluid containing unwanted wastes, mostly excess water, salts, and nitrogen compounds. The major organs of the urinary system are the kidneys, a pair of bean-shaped organs that continuously filter substances from the blood and produce urine. Urine flows from the kidneys through two long, thin tubes called ureters. With the aid of gravity and wavelike contractions, the ureters transport the urine to the bladder, a muscular vessel. The normal adult bladder can store up to about 0.5 liter (1 pt) of urine, which it excretes through the tubelike urethra. An average adult produces about 1.5 liters (3 pt) of urine each day, and the body needs, at a minimum, to excrete about 0.5 liter (1 pint) of urine daily to get rid of its waste products. Excessive or inadequate production of urine may indicate illness and doctors often use urinalysis (examination of a patient’s urine) as part of diagnosing disease. For instance, the presence of glucose, or blood sugar, in the urine is a sign of diabetes mellitus; bacteria in the urine signal an infection of the urinary system; and red blood cells in the urine may indicate cancer of the urinary tract. The kidneys lie embedded in fat tissue on either side of the backbone at about waist level. Each fist-sized kidney is reddish-brown, weighs 140 to 160 g (5 to 6 oz), and is similar in shape to the kidney beans sold at the supermarket. On the inner border of each kidney is a depression called the hilum, where the renal artery, the renal vein, and the ureter connect with the kidney (the adjective renal is from the Latin term renalis, meaning of or near the kidneys). The renal artery delivers over 1700 liters (450 gal) of blood to the kidneys each day, which these organs filter and return to the heart via the renal vein. Each kidney contains about 1 million microscopic coiled channels, called nephrons, which perform this critical blood-filtering function and produce urine in the process. The outer skin of the kidney is called the renal capsule (renal refers to the kidney). If you were to slice through a kidney from side to side and open it like the pages of a book, you would see two main parts, a central part and an outer, peripheral part (Figure 2b). The peripheral part consists of the cortex and the medulla, with the medulla consisting of medullary pyramids; the inner, central part consists of a group of tubes (the calyx and the pelvis) that lead out of each pyramid and into the ureter (the tube that drains urine into the bladder). Within the cortex and the medullary pyramids are found millions of tiny structures called nephrons (Figure 2c). The nephrons are responsible for filtering out of the bloodstream an estimated 43 gallons of water a day- about twice the body's entire weight in fluid - through an intricate network of tubules (little tubes The shape of a nephron is unique, unmistakable, and admirably suited to its function of producing urine (Figure 2c).It looks a little like a big "mouth" hooked to a really long and winding neck. The "mouth" is filled with what looks like a round jawbreaker that is so big that the "mouth" cannot close! In reality, the nephron is composed of two main parts: the renal corpuscle (the mouth and the jawbreaker) and the renal tubule (the long and winding neck). The "mouth" of the renal corpuscle is actually called Bowman's capsule and the " jawbreaker" is actually called the glomerulus from the Latin word for "small ball" (the plural form is glomeruli). The glomerulus is a network of blood capillaries that is surrounded, first, by a double membrane (the glomerular capsular membrane) and then is surrounded by Bowman's capsule. The renal tubule (the long and winding neck) consists of the proximal tubule (the thick, winding part of the neck that extends just up to where it begins to make a U-turn); the loop of Henle (the thinner part of the neck that actually makes the U-turn); and the distal tubule (the last, thicker part of the neck that travels away from the U-turn, winds all around, and eventually leads into collecting tubules). Now that you are familiar with the structure of the kidney and, in particular, the nephron, let's see how the whole system works to produce urine so that waste products can be removed from the body.