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Beyond Mendelian Inheritance Incomplete dominance - When the resulting phenotype is a blend of a heterozygous allele pair: red flower + blue flower = purple flower The allele for red flower would be FR and the allele for blue flower would be FB. Can you complete the genotypes and phenotypes on your paper? Genotype Phenotype Codominance - When the resulting phenotype shows both traits of an allele pair: red flower + blue flower = red and blue spotted flowers The allele for red flower would be R and the allele for blue flower would be B. Can you complete the genotypes and phenotypes on your paper? Genotype Phenotype Multiple Alleles - When there are more than 2 variations. EX: Human blood types have 3 different alleles, A, B, and O. Genotypes Phenotypes AA, AO A blood type AB AB blood type BB, BO B blood type OO O blood type Regulatory Genes -Regulate the expression of other genes. It may “silence” another gene from expressing its dominant trait. EX: Manx cats have no tails because there is a gene that “silences” the gene for a tail. The tail silencing gene has the possible alleles: S – “silences” tail = no tail s – doesn’t “silence” tail = tail Question: Can Manx cats without tails have a kitten with a tail? Show your answer with a Punnett Square. Applying these patterns to Harry Potter: 1. Hagrid’s father was a wizard and his mother was a giantess. The normal heights for giants and wizards are: Giants = 20 ft & Wizards = 5 ft 6in. Given that Hagrid is described as being 12 ft tall, what type of genetic inheritance may be at work? 2. In the Harry Potter series, characters are born with or without magical ability. Those with magical abilities also show very strong, normal, and weak abilities. Therefore, there are two genes involved in magical abilities: Gene 1 = Expression – the character has or doesn’t have magical ability Gene 2 = Strength – the character has strong, average, or weak magical abilities A. Given the information above, complete the chart for the possible phenotypes and genotypes for gene 1. Phenotype Genotype(s) **This is an example of what type of inheritance? __________________________________________ B. Given the information above, complete the chart for the possible phenotypes and genotypes for gene 2. Phenotype Genotype **This is an example of what type of inheritance? __________________________________________ 3. Using charts you completed in number 2 and the following phenotypes for the characters from the books, can you come up with their genotypes? HINT – You’ll have 4 letters for each. Character Phenotype Harry Very strong magical ability Ron Average magical ability Aunt Petunia* No magical ability Mr. Filch Weak magical ability * Aunt Petunia has MANY possible genotypes! Genotype(s) 4. Since Hermione has average magical ability, what are the possible genotypes of her parents? HINT: Write Hermione’s genotype first: _________ Applying these patterns to Harry Potter: 1. Hagrid’s father was a wizard and his mother was a giantess. The normal heights for giants and wizards are: Giants = 20 ft & Wizards = 5 ft 6in. Given that Hagrid is described as being 12 ft tall, what type of genetic inheritance may be at work? 2. In the Harry Potter series, characters are born with or without magical ability. Those with magical abilities also show very strong, normal, and weak abilities. Therefore, there are two genes involved in magical abilities: Gene 1 = Expression – the character has or doesn’t have magical ability Gene 2 = Strength – the character has strong, average, or weak magical abilities a. Given the information above, complete the chart for the possible phenotypes and genotypes for gene 1. Phenotype Genotype(s) **This is an example of what type of inheritance? __________________________________________ 2. In the Harry Potter series, characters are born with or without magical ability. Those with magical abilities also show very strong, normal, and weak abilities. Therefore, there are two genes involved in magical abilities: Gene 1 = Expression – the character has or doesn’t have magical ability Gene 2 = Strength – the character has strong, average, or weak magical abilities Given the information above, complete the chart for the possible phenotypes and genotypes for gene 2. Phenotype Genotype **This is an example of what type of inheritance? __________________________________________ 3. Using charts you completed in number 2 and the following phenotypes for the characters from the books, can you come up with their genotypes? HINT – You’ll have 4 letters for each. Character Phenotype Genotype(s) Harry Very strong magical ability Ron Average magical ability Aunt No magical Petunia* ability Mr. Filch Weak magical ability * Aunt Petunia has MANY possible genotypes! 4. Since Hermione has average magical ability, what are the possible genotypes of her parents? HINT: Write Hermione’s genotype first: _________ (You will need data from table in 3)