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n°30 June 2016
n°30 June 2016

... our database (2,3). Figure 3 shows the heart rate trends, together with the related ECG strips in a given individual, a few seconds before spontaneous atrial fibrillation occurrence. The RR interval lengthening is obvious, suggesting a bradycardia dependent phenomenon, and or a vagally induced arrhy ...
Three-dimensional organization of electrical turbulence in the heart
Three-dimensional organization of electrical turbulence in the heart

... Rotors occur in systems that are called excitable, i.e., systems that have two main properties: excitability ~ability to conduct waves of excitation! and refractoriness ~ability to recover and conduct another wave of excitation after some period of time called the refractory period!. Such rotors wer ...
Task Force Report Task Force on Sudden Cardiac Death of the
Task Force Report Task Force on Sudden Cardiac Death of the

... deaths that occur unwitnessed, such as being found dead in bed. Most authors have erred in favour of classifying such events as SCDs, even though it is often impossible to define when the patient was last alive or for what duration he suffered any symptoms prior to death. This document will propose r ...
Sodium Channel Mutations and Susceptibility to Heart Failure and
Sodium Channel Mutations and Susceptibility to Heart Failure and

... heart failure and the primary indication for cardiac transplantation,1 has an incidence of 6.0 per 100000 person-years and prevalence of 36.5 per 100000 population.2 Dilated cardiomyopathy is familial in more than 20% of cases,3 implicating genetic defects in single proteins in the disease pathogene ...
European Journal of Heart Failure
European Journal of Heart Failure

... the effect of adaptive servo ventilation (ASV) added to optimal medical therapy on outcomes in patients with heart failure and reduced ejection fraction (HFrEF) and predominant central sleep apnoea (CSA).1 The main study findings were neutral with respect to the primary endpoint, which was the time ...
High Blood Pressure and Hypertension
High Blood Pressure and Hypertension

... the day. When blood pressure stays elevated over time, it is called high blood pressure or hypertension. High blood pressure is dangerous because it makes the heart work too hard and contributes to atherosclerosis (hardening of the arteries). It increases the risk of heart disease and stroke, which ...
The chambers of the heart A- The right atrium: 1
The chambers of the heart A- The right atrium: 1

... There are two opening in left atrium : 1-Pulmonary Vein opening The pulmonary vein is the vessel transporting oxygen-rich blood from the lungs to the left atrium. (seven to eight in number in horse and five in sheep) found caudal to auricle on the right side of atrium 2- left atrioventricular orific ...
Total Dissolved Solids
Total Dissolved Solids

... as caffeine or nicotine in the blood, and the age of the person. As a rule, the maximum heart rate of all individuals of the same age and sex is about the same. However, the time it takes individuals to reach that maximum level while exercising varies greatly. Since physically fit people can deliver ...
ACQUIRED VITIUMS
ACQUIRED VITIUMS

... opening snap – valve is turned over by the blood stream praesystolic increasing diastolic murmur (in case of atrial fibrillation there is a silent, hardly recognizable murmur) ECG: P mitrale - left atrial overload CHEST XRAY: mitral configuration-enlarged left atrium, heart border passes the sternum ...
Risk and prevention of pneumococcal diseases among
Risk and prevention of pneumococcal diseases among

... increased gradually from 24.8 admissions/100 patient-years at risk in 1991 to 30.6 admissions/100 patient-years at risk in 2001.1 S pneumoniae is responsible for up to 53% of reported pneumonia cases in dialysis patients.34 Mortality rates after pneumonia in dialysis patients: up to 14- to 16fold gr ...
H P O L
H P O L

... all hemodynamic parameters except PAWP. PVH and OPVH patients were hemodynamically similar except for mPAWP pre-saline. PAH patients had significantly lower cardiac output and cardiac index than PVH and OPVH patients and their mRAP was lower than that of PVH, while their mPAP was slightly higher th ...
evaluation of a patient with suspected pulmonary hypertension.
evaluation of a patient with suspected pulmonary hypertension.

... routinely made diagnosis in cardiology and pulmonary clinics. It is essential for medical practioners to have a high index of clinical suspicion of this devastating disease as early diagnosis may affect the survival. Pulmonary hypertension is defined as mean pulmonary artery pressure more than 25 mm ...
Irbesartan in Patients with Heart Failure and Preserved
Irbesartan in Patients with Heart Failure and Preserved

... ed worsening heart failure, myocardial infarction, stroke, unstable angina, ventricular or atrial dysrhythmia, or myocardial infarction or stroke that occurred during any hospitalization. The secondary outcomes were the components of the primary outcome (death from any cause and hospitalization for ...
PRACTICE Matters T C
PRACTICE Matters T C

... Patients at this (“pre-CHF”) stage have risk factors associated with the development of CHF but do not have any identifiable structural or functional cardiac abnormalities. The goal of treatment for stage A patients is the prevention of structural changes in the heart by identifying and aggressively ...
Cardiac cycle
Cardiac cycle

... – when semilunar valves closes AV valves is not yet open because pressure in vetricles still exceeeds that of atria. – Therefore all valves are once again closed for short period of time when ventricles are relaxing ...
CHFmodule FY2011Q2
CHFmodule FY2011Q2

... Enter a date that is as specific as possible. If only the year is available, use 01/01/yyyy. Information may have to be extrapolated from notes such as “patient’s EF three years ago was 45,” etc. If the patient’s LVSF is documented but the date of the test cannot be found, enter 99/99/9999 default d ...
3 Ventricular Function
3 Ventricular Function

... increased fiber stretch, which in turn causes length activation, thought to be explicable in part by sensitization of the contractile proteins to the prevailing cytosolic calcium concentration. An increased afterload may indirectly, through stimulation of stretch-sensitive channels, increase cytosol ...
AHS CVS Lecture 6
AHS CVS Lecture 6

... Baroreceptor Reflex in Response to a Decrease in MAP MAP Arterial baroreceptors Frequency of ...
lithuanian university of health sciences
lithuanian university of health sciences

... concentration was determined by rapid quantitative immunofluorescence method "Triage Cardiac, Biosite Diagnostics" (Germany). This method is used to determine all types of TnI: free TnI, TnI-C and TnI-C-T contained in compounds. The lowest concentration of TnI determined by Triage Cardiac method is ...
Contraction Mechanisms in Cardiac Muscle
Contraction Mechanisms in Cardiac Muscle

... Mechanism of Calcium-induced Calcium Release through the Ryanodine Receptors (RyR) at the Sarcoplasmic Reticulum 1. When the myocytes are excited, the action potential spreads through sarcolemma and travels down to the transvers tubules. 2. The action potential will open Voltage-gated L-type calcium ...
The Anatomy and Function of the Semilunar Valves
The Anatomy and Function of the Semilunar Valves

... valvar complex is a dynamic structure with its geometric parameters changing continuously throughout the phases of the cardiac cycle and relative to the associated changes in pressure that will occur within the aortic root [14]. For example, from diastole to systole, the relative changes in diameter ...
Nitroglycerin increases venous return but reduces CVP: a preload
Nitroglycerin increases venous return but reduces CVP: a preload

... pressure. This last element can be used as a parameter for effective circulating blood volume. The main problem with this parameter is that it cannot be easily measured in clinical practice, but only in experimental stop-flow models. Based on the Guytonian concepts, a clinical decision support syste ...
Guidelines ESC EACTS 2014 Guidelines on myocardial
Guidelines ESC EACTS 2014 Guidelines on myocardial

... Revascularization in patients requiring valve interventions . . . 12.1 Primary indication for valve interventions . . . . . . . . . . 12.2 Primary indication for coronary revascularization . . . . . Associated carotid/peripheral artery disease . . . . . . . . . . . 13.1 Associated coronary and carot ...
2014 ESC/EACTS Guidelines on myocardial
2014 ESC/EACTS Guidelines on myocardial

... from giving full and careful consideration to the relevant official, updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient’s case in light of the scientifically accepted data pursuant to their respective ethical and professional obli ...
Effect of aging on heart and ileum histology of male albino rats
Effect of aging on heart and ileum histology of male albino rats

... support because it is consistent with many of the processes and degenerative diseases observed with aging (Harman, 1998 ; Julian and Leeuwenburgh , 2004). The most evident and well-understood age-related effects on skeletal muscle and heart are loss of muscle mass (or sarcopenia) and a significant h ...
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Coronary artery disease



Coronary artery disease (CAD), also known as ischemic heart disease (IHD), atherosclerotic heart disease, atherosclerotic cardiovascular disease, and coronary heart disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden coronary death. It is within the group of cardiovascular diseases of which it is the most common type. A common symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck, or jaw. Occasionally it may feel like heartburn. Usually symptoms occur with exercise or emotional stress, last less than a few minutes, and gets better with rest. Shortness of breath may also occur and sometimes no symptoms are present. The first sign is occasionally a heart attack. Other complications include heart failure or an irregular heartbeat.Risk factors include: high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol, among others. Other risks include depression. The underlying mechanism involves atherosclerosis of the arteries of the heart. A number of tests may help with diagnoses including: electrocardiogram, cardiac stress testing, coronary computed tomographic angiography, and coronary angiogram, among others.Prevention is by eating a healthy diet, regular exercise, maintaining a healthy weight and not smoking. Sometimes medication for diabetes, high cholesterol, or high blood pressure are also used. There is limited evidence for screening people who are at low risk and do not have symptoms. Treatment involves the same measures as prevention. Additional medications such as antiplatelets including aspirin, beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) may be used in severe disease. In those with stable CAD it is unclear if PCI or CABG in addition to the other treatments improve life expectancy or decreases heart attack risk.In 2013 CAD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CAD for a given age has decreased between 1980 and 2010 especially in the developed world. The number of cases of CAD for a given age has also decreased between 1990 and 2010. In the United States in 2010 about 20% of those over 65 had CAD, while it was present in 7% of those 45 to 64, and 1.3% of those 18 to 45. Rates are higher among men than women of a given age.
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