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Bahrain Medical Bulletin, Vol.22, No.1, March 2000
Bahrain Medical Bulletin, Vol.22, No.1, March 2000

... lung can also have abnormal structure11. The prognosis of Scimitar syndrome depends on the age of detection. Patients in whom the diagnosis was made during the first year of life had more severe symptoms, higher rate of heart failure and pulmonary hypertension than did the patients in whom the diagn ...
EISENMENGER SYNDROME
EISENMENGER SYNDROME

... failure.He improved with rest and digitalis, but collapsed and died more or less suddenly on November 13 following a large haemoptysis. At necropsy , a 2 – to 2.5 cm defect was found in the perimembranous septum along with overriding of aorta” ...
EISENMENGER SYNDROME
EISENMENGER SYNDROME

... failure.He improved with rest and digitalis, but collapsed and died more or less suddenly on November 13 following a large haemoptysis. At necropsy , a 2 – to 2.5 cm defect was found in the perimembranous septum along with overriding of aorta” ...
Inherited cardiac arrhythmia syndromes: What have they taught us
Inherited cardiac arrhythmia syndromes: What have they taught us

... arrhythmias despite having structurally normal hearts. It has also been known for over 40 years that these rare instances of “unexplained sudden death” were often familial and so likely to have a genetic basis.5,6 In the past 10 years the genetic basis of many of these rare congenital arrhythmia syn ...
Miscellaneous Cardiac Diseases
Miscellaneous Cardiac Diseases

... z Complete absence of left side gives levoposition of heart z Diaphragmatic surface z Total bilateral absence z Right sided z ...
Print this article - Publicatii USAMV Cluj
Print this article - Publicatii USAMV Cluj

... subvalvular. The subvalvular form (subaortic stenosis) is the most common form in the dog. With this defect, a ibrous band or ring located just below the aortic semilunar valves impedes left ventricular emptying. Aims: We want to underline clinical and paraclinical abnormalities associated with this ...
full text
full text

... b/ Mitral regurgitation c/ Aortic regurgitation ...
An anatomical basis for the Neck-Tongue Syndrome
An anatomical basis for the Neck-Tongue Syndrome

... abnormal subluxation of that joint then the likelihood of inpaction would be greater. It may be questioned whether compression or irritation of proprioceptive fibres from the tongue could cause numbness. However, it is well known that patients with Bell's palsy frequently complain of "numbness" alth ...
Brief Review - Hypertension
Brief Review - Hypertension

... Effects of wave reflection are readily measured in terms of augmentation of the central (carotid, aortic, and left ventricular) pressure waveform. The aortic and left ventricular waveforms may be measured invasively during cardiac catheterization41– 43 or synthesized from the radial pressure wavefor ...
Brugada Syndrome and Vasovagal Syncope
Brugada Syndrome and Vasovagal Syncope

... The Brugada syndrome is characterized by ST-segment elevation in the right precordial leads V1 through V3 and an episode of venricular tachyarrythmia in the absence of structural heart disease.1-3 Patients with spontaneously or inducible Brugada type-1 morphology are at high risk of polymorphic vent ...
Biventricular and atrial diastolic function assessment using
Biventricular and atrial diastolic function assessment using

... vital role in regulating the bioactivity of transforming † This study was performed at St George’s University of London and St George’s Hospital NHS Trust, London, UK. ...
Valvular Heart Disease - Nursing PowerPoint Presentations
Valvular Heart Disease - Nursing PowerPoint Presentations

... • Complications include severe MR, residual ASD, myocardial perforation, emboli, MI and death. • Overall event-free survival is 50% to 65% over 3-7 years. • The underlying mitral valve morphology is the most important factor in determining outcome. • Relative contraindications include the presence o ...
双源CT Flash Spiral技术对主动脉成像的辐射剂量及升主动脉图像
双源CT Flash Spiral技术对主动脉成像的辐射剂量及升主动脉图像

... CTA in this study, including 45 cases in Group A and 48 cases in Group B. They were all divided into 3 types according to DeBakey classification. The intimal tear of Type I and II occured in the the ascending aorta near the sinotubular junction, which coincided with intraoperative findings. In Group ...
MRI of acute stroke.A.
MRI of acute stroke.A.

... cerebrovascular anomalies such as intracranial aneurysms and arteriovenous malformations (AVMs). ...
Diagnosis and Treatment of Sick Sinus Syndrome -
Diagnosis and Treatment of Sick Sinus Syndrome -

... dysfunction is severe but intermittent. In these cases, patients can carry a pocket-sized device for transmitting ECG readings via telephone when they are having symptoms. For this procedure to be successful, the arrhythmia must last for at least one minute. Another approach is to have patients acti ...
Coexistence of bicuspid aortic valve, aberrant right subclavian artery
Coexistence of bicuspid aortic valve, aberrant right subclavian artery

... Bicuspid aortic valve (BAV) is a heritable condition, in which the aortic valve has only two leaflets. With this deformity, the valve’s function is usually impaired and the entity is associated with significant morbidity and mortality including aortic valve stenosis or regurgitation, as well as dila ...
Wolff-Parkinson-White Syndrome: An Uncommon Cause of
Wolff-Parkinson-White Syndrome: An Uncommon Cause of

... revealed that the patient was doing well without any recurrence of dysrhythmia. DISCUSSION The case patient’s ECG shows a rapid, wide QRS complex tachycardia (Figure 1), which is defined as tachycardia having a QRS duration greater than 120 msec (0.12 sec). Wide complex tachycardias are often caused ...
Transcatheter Aortic Valve Replacement
Transcatheter Aortic Valve Replacement

... 1. Severe native valve aortic stenosis or failure defined by ≥ 1 of the following: a. Mean aortic valve gradient ≥ 40mmHg b. Peak jet velocity ≥ 4.0 m/s c. Aortic valve area (AVA) < 0.8 cm2 d. AVA Index < 0.6 cm2/m2 2. Presence of New York Heart Association (NYHA) symptoms ≥ class II 3. Inoperable o ...
2014 - Dr. Dhiren Shah
2014 - Dr. Dhiren Shah

... aortic valve gradients can be challenging. Although data for surgical intervention are not as robust for these patient subsets as for patients like Mr. A, several case series have suggested that survival in these patients is significantly better with surgery than with medical therapy alone. Specific ...
Diagnosis and Treatment of Bicuspid Aortic Valve Disease
Diagnosis and Treatment of Bicuspid Aortic Valve Disease

... Because the life expectancy is long for these patients, bioprosthetic or mechanic valve implantation is controversial. With the third generation bioprosthetic valves, in 80% of the patients, there was no need for another operation in the next 12 years (21). New generation stent-free bioprosthesis ar ...
The Left Main Complication of the Bentall`s Procedure
The Left Main Complication of the Bentall`s Procedure

... The Bentall’s procedure involves a composite graft and coronary artery reimplantation to treat both an aneurysm of the aorta and aortic valve disease. We have previously reported ostial coronary pseudoaneurysm formation in a consecutive series of patients following Bentall’s surgery [1, 2]. This con ...
TRANSCATHETER AORTIC VALVE REPLACEMENT: REVIEw AND
TRANSCATHETER AORTIC VALVE REPLACEMENT: REVIEw AND

... eral arteries, alternative routes of delivery include French (7.3 – 8 mm), which resulted in an initial the subclavian artery, the ascending aorta via a small 30-day rate of peripheral vascular complication of upper sternotomy, or directly through the left ven16.8%.13 In addition, for patients deeme ...
interstitial keratitis and deafness in a patient with
interstitial keratitis and deafness in a patient with

... optic nerve involvement (6). Corneal involvement is extremely rare (4), but interstitial keratitis has been reported (6). Only a few cases of hearing loss associated with sarcoidosis have been documented (2,5,8,11). Since there are no definitive diagnostic tests, the presence of non-caseating granul ...
Aortic Root Pseudoaneurysm Following Surgery for Aortic Valve
Aortic Root Pseudoaneurysm Following Surgery for Aortic Valve

... and to the patch used to reconstruct the left ventricular outflow tract. Although this maneuver may offer another option to avoid such a pseudoaneurysm complication, it is technically demanding and with the probability of patch dehiscence and recurrent prosthetic valve endocarditis. The hemodynamics ...
Severe coronary artery ectasia and abdominal aortic aneurysm
Severe coronary artery ectasia and abdominal aortic aneurysm

... iliac arteries and an AAA. Further examination by computed tomography confirmed an infrarenal, calcified aneurysm of nearly 6 cm in diameter (fig. 2). With medical treatment the patient could be mobilised without complications and remained free of chest pain during the further hospital course. After ...
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Marfan syndrome



Marfan syndrome (also called Marfan's syndrome) is a genetic disorder of connective tissue. It has a variable clinical presentation, ranging from mild to severe systemic disease. The most serious manifestations involve defects of the heart valves and aorta, which may lead to early death if not properly managed. The syndrome also may affect the lungs, eyes, dural sac surrounding the spinal cord, the skeleton, and the hard palate. People with Marfan syndrome tend to be unusually tall, with long limbs and long, thin fingers and toes.The syndrome is caused by the misfolding of fibrillin-1, a glycoprotein which forms elastic fibers in connective tissue and contributes to cell signaling activity by binding to and sequestering transforming growth factor beta (TGF-β). The mutated fibrillin binds poorly to TGF-β, which results in an accumulation of excess TGF-β in the lungs, heart valves, and aorta. This in turn causes abnormal structure and function of vascular smooth muscle and reduced integrity of the extracellular matrix, which weaken the tissues and cause the features of Marfan syndrome.Named after Antoine Marfan, the French pediatrician who first described the condition in 1896, the disease is an autosomal dominant disorder. Management often includes the use of angiotensin II receptor antagonists (ARBs) and beta blockers.
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