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Pou And Pneumoia
Pou And Pneumoia

... Jews, with short recurrent attacks of fever, pain in the abdomen, chest, or joints, and erythema like that of erysipelas; it may be complicated by amyloidosis. ...
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Blood thicker than water: kinship, disease prevalence and group
Blood thicker than water: kinship, disease prevalence and group

... first line response to M. bovis exposure, whereas the serological response (as measured by the ELISA test and StatPak) takes time to develop as infection progresses [39]. Some individuals then go on to become ‘infectious’, characterized by the excretion of M. bovis bacteria via various routes [40,41 ...
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Neuro 26

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Replication of hepatitis C virus in peripheral blood mononuclear
Replication of hepatitis C virus in peripheral blood mononuclear

... Infection with hepatitis C virus (HCV) causes chronic hepatitis, which may lead to liver cirrhosis and subsequently to hepatocellular carcinoma (HCC). HCV is a primarily hepatotropic virus, but hepatocytes are not the only localization of its replication. Extrahepatic replication is well recognized ...
Potential Reduction of Mortality from Invasive Pneumococcal
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What is the evidence for the effectiveness of

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... Treatment. In similar fashion, the risk of working with infectious agents decreases if effective treatment is available. Effective treatments include the use of vaccines, specific immune globulin, antibiotics and antivirals. Other Risk Factors. In addition to the major risk factors discussed above, ...
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Rodents as reservoirs of human pathogens in Bulgaria

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... proofreading activity of the viral DNA polymerase (3, 5, 6). While recent estimates suggest a higher point mutation rate for poxviruses compared to other dsDNA viruses (7, 8), these rates are still lower than that of most RNA viruses. Observations that viruses with varying mutation rates flourish in ...
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Dengue Patients with Early Hemorrhagic Manifestations Lose

... due to higher levels in DHF compared with DF, and a correlation with thrombocytopenia and raised alanine transferase.21 IL-10 exhibits anti-inflammatory properties, including the inhibition of inflammatory responses, antigen presentation, and phagocytosis. In some cases, IL-10 may play a role in DEN ...
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Feline Immunodeficiency Virus (FIV) and Feline

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Chapter 19

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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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