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Smallpox - Issaquah Connect
Smallpox - Issaquah Connect

... Smallpox spreads through the air, is inhaled by its victims, and once inside it multiplies in the lymph glands. From there it accesses the bloodstream and targets all the major organs. Here it spends 2 weeks multiplying until the first outward signs of the illness appear. Sore throat, headache, feve ...
Reprint
Reprint

... phenomenological way (see e.g. Refs [11,12,14,15]). Recent work has developed an explicit description of the within-host dynamics of pathogen replication and the defensive response of the host, and nested this into the traditional between-host models of pathogen evolution (Box 1). This approach prov ...
Kristina Narfstrom, DVM, PhD, DipECVO
Kristina Narfstrom, DVM, PhD, DipECVO

... areas of southwestern United States, but cases may occur elsewhere through the mobility of the canine population. Coccidioidomycosis is mainly caused by inhalation of spores, whereas transmission from animal to animal is rare, apparently because the endospores are too fragile. Thus, Coccidiodes immi ...
Case A - sfcdcp
Case A - sfcdcp

... *Believed previously vaccinated for measles  Had contact with a known measles case on Jan. 17, 2009 while traveling in England  Flew back to U.S. on Jan. 20, 2009  On Jan. 25, 2009, 8 days after contact, developed measles symptoms: - malaise & fever followed by descending rash - cough developed J ...
Mechanisms of pathogenesis, infective dose and virulence in human
Mechanisms of pathogenesis, infective dose and virulence in human

... is that closely related species can share characters through common descent rather than independent evolution. Consequently, analysing species as independent data points can lead to misleading correlations [4–6]. For example, all viruses are locally acting, and so this could lead to patterns between ...
Chickenpox - Spokane Regional Health District
Chickenpox - Spokane Regional Health District

... syndrome or necrotizing fasciitis, a dangerous skin/tissue infection. Complications of chickenpox are rare but can occur. Bacterial infections, as well as pneumonia, can occur in infants, adults, pregnant women, and immune compromised persons. Diarrhea and dehydration are also a risk. Consult with a ...
Chlamydia is a sexually transmitted disease caused by an organism
Chlamydia is a sexually transmitted disease caused by an organism

... Women who have chlamydia may also be more likely to get HIV, the virus that causes AIDS, from a person who is infected with HIV. Because of the symptoms associated with chlamydia, infected individuals have a three- to five-fold increase in the risk of acquiring HIV (the virus that causes AIDS) if ex ...
Chlamydia is a sexually transmitted disease
Chlamydia is a sexually transmitted disease

... Women who have chlamydia may also be more likely to get HIV, the virus that causes AIDS, from a person who is infected with HIV. Because of the symptoms associated with chlamydia, infected individuals have a three- to five-fold increase in the risk of acquiring HIV (the virus that causes AIDS) if ex ...
A Review of Zoonotic Tuberculosis at the Human-Livestock
A Review of Zoonotic Tuberculosis at the Human-Livestock

... United States–Mexico border in the Baja California region. Pediatrics 105, E79 de Kantor, I. N., LoBue, P. A. and Thoen C. O. 2010. Human Tuberculosis Caused by Mycobacterium bovis in the United States, Latin America, and the Caribean. International Journal on Tuberculosis and Lung Disease 14(11): 1 ...
Tetanus in an unvaccinated child in the United Kingdom: case report
Tetanus in an unvaccinated child in the United Kingdom: case report

... Tetanus is a vaccine preventable disease and is more common in developing countries. Despite widespread availability of safe and effective vaccine against tetanus, a total of 175 cases have been reported in England and Wales during the period 1984– 2000 and 11 per cent of these were in people eligib ...
Addressing Emerging Pandemic Threats
Addressing Emerging Pandemic Threats

... • Type of microbe: virus (6), bacteria (1) • Direct human-to-human transmission (6) • Some acute (5), others protracted (2) • Potential for very high mortality • Low mortality does not equal low economic impact • Impact can vary considerably across countries** • Only one (SARS) was contained by (non ...
Primary High-Dose Murine Norovirus 1 Infection Fails To
Primary High-Dose Murine Norovirus 1 Infection Fails To

... magnitude of protection afforded by a primary MNV-1 infection inversely correlates with the inoculum dose. Future studies will elucidate the mechanisms by which noroviruses avoid the induction of protective immunity and the role played by the inoculum dose in this process, ultimately translating thi ...
Signs and symptoms of nematode disease
Signs and symptoms of nematode disease

... symptomatic plants is common for nematodes of all life cycle strategies. These patches may grow in size over time if nematodes are not treated. Damage is variable, ranging from mildly chlorotic (yellowing) areas to patches where plants are severely stunted and plant density is low. Plants in these p ...
Healthcare Associated Infections - Environmental Public Health Today
Healthcare Associated Infections - Environmental Public Health Today

... Occurs most often in elderly people and people with certain medical problems Causes diarrhea and other serious intestinal conditions Transmission ◦ Contaminated bed linens, bed rails, bathroom fixtures and medical equipment ◦ Person to person on the hands of hospital personnel and ...
West Nile Virus - Nicholas Kurek`s Portfolio
West Nile Virus - Nicholas Kurek`s Portfolio

... Unfortunately, some people may not be able to give nor have family available to provide a history. Clinically, the manifestation of WNV may be similar to other viral infections and may not necessarily be readily diagnosed. The CDC (2013) states: Less than 1% of infected persons develop neuroinvasive ...
About Conjunctivitis or “Pink Eye”
About Conjunctivitis or “Pink Eye”

... About Conjunctivitis or “Pink Eye” What is conjunctivitis? Conjunctivitis is more commonly referred to as pink eye. The whites of the eyes appear pink or red when the conjunctiva (the transparent membrane which lines part of the eyeball) becomes inflamed or infected.1 Though pink eye can be irritati ...
FIV Feline Immunodeficiency Virus
FIV Feline Immunodeficiency Virus

... the immune system of a cat. The virus lives in the blood of the infected cat and is carried in its system throughout its life. Cats infected with FIV may remain healthy for up to 10 years. While some infected cats show no signs of the disease, others may display initial symptoms such as: ...
Aquatic invasive species and emerging infectious disease threats: A
Aquatic invasive species and emerging infectious disease threats: A

... An estimated 60– 75% of the world’s infectious diseases of humans are zoonotic, infecting both humans and other animals. Many are vectorborne, relying on transmission by mosquitoes and biting flies that are aquatic for much of their lifespan. Others rely on aquatic molluscs, fishes, or other aquatic ...
Pathology 18 p882-888 [9-2
Pathology 18 p882-888 [9-2

...  Perforation, cholangitis, rupture, fistula, or cancer are complications Disorders of the Extrahepatic Bile Ducts o Choledocholithiasis and Ascending Cholangitis = presence of stones withinthe bile ducts of biliary tree (higher in Asia; pigmented) and bacterial infection of bile ducts (obstruction) ...
Hepatitis C Update
Hepatitis C Update

... Hepatitis B Immune Globulin (HBIG) • Prepared from plasma containing high titers of antibody to HBsAg • Used for post-exposure prophylaxis to prevent infection ...
Highly Communicable Respiratory Diseases IC0026 - nc
Highly Communicable Respiratory Diseases IC0026 - nc

... 2. In the presence of highly communicable respiratory disease activity in North Carolina (but no cases within UNC Health Care facilities): a. Signs (in appropriate languages including English and Spanish) will be placed outside the Emergency Department (ED) and other hospital entrances requesting th ...
EMD Departmental Brochure and Faculty Profiles
EMD Departmental Brochure and Faculty Profiles

... next generation of leaders in who will take up this challenge, both locally and globally. EMD, as one of the few stand-alone infectious disease epidemiology departments, has crosscutting, synergistic expertise in field epidemiology, laboratory and translational research, and quantitative methods and ...
Study Session 2 Prevention and Control of Communicable Diseases
Study Session 2 Prevention and Control of Communicable Diseases

... Following detection of an infectious disease, you may need to separate patients from others to prevent transmission to healthy people. This is called isolation. It is not indicated for every infection, but it is important to isolate people with highly severe and easily transmitted diseases. For exam ...
Management of Chronic Infectious Diseases in Schoolchildren
Management of Chronic Infectious Diseases in Schoolchildren

... Historically, the Management of Chronic Infectious Diseases in Schoolchildren was developed by a task force that was formed in 1985. This task force was charged with the responsibility of developing recommendations to assist school policymakers to establish reasonable and practical guidelines for sc ...
Smallpox
Smallpox

... distinctive rash is produced (see above) which is wholly characteristic in the great majority of cases. The rash is most dense over the face and hands – unclothed and readily visible portions of the body. Experiences from the eradication campaign indicate that, in the presence of a strong surveillan ...
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African trypanosomiasis



African trypanosomiasis or sleeping sickness is a parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei. There are two types that infect humans, Trypanosoma brucei gambiense (T.b.g) and Trypanosoma brucei rhodesiense (T.b.r.). T.b.g causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.Initially, in the first stage of the disease, there are fevers, headaches, itchiness, and joint pains. This begins one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness and trouble sleeping. Diagnosis is via finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first and second stage disease.Prevention of severe disease involves screening the population at risk with blood tests for T.b.g. Treatment is easier when the disease is detected early and before neurological symptoms occur. Treatment of the first stage is with the medications pentamidine or suramin. Treatment of the second stage involves: eflornithine or a combination of nifurtimox and eflornithine for T.b.g. While melarsoprol works for both it is typically only used for T.b.r. due to serious side effects.The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. As of 2010 it caused around 9,000 deaths per year, down from 34,000 in 1990. An estimated 30,000 people are currently infected with 7000 new infections in 2012. More than 80% of these cases are in the Democratic Republic of the Congo. Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. Other animals, such as cows, may carry the disease and become infected.
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