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Why infectious disease research needs community ecology
Why infectious disease research needs community ecology

... For example, long-term sampling of wild field vole (Microtus agrestis) populations revealed that infection with the protozoan Babesia microti reduced the probability that a host subsequently became infected with the bacteria Bartonella spp.; however, if Bartonella established first, then B. microti ...
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... Etiology: 3 major antigenic groups represented by Kilham’s rat virus (KRV or RV), Toolan’s H-1, rat parvovirus (RPV, formerly ROPV, rat orphan parvovirus); conserved nonstructural proteins so IFA for serodetection; small, single strand DNA, nonenveloped. Transmission: oronasal, fomites, transplacent ...
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... Most infections have no clinical signs Sero-conversion, virus elimination and life-long immunity ...
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... Source: United States Centers for Disease Control and Prevention Disclaimer: This document has been provided as an informational resource for Aon clients and business partners. It is intended to provide general guidance on potential exposures, and is not intended to provide medical advice or address ...
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... and other animal health. If seropositive animals are found: 1) ensure all milk is properly pasteurized; 2) disinfect animal facilities regularly, especially parturition areas, with a 10% bleach solution; 3) keep pregnant animals in separate pens; 4) always quickly remove all birthing matter, includi ...
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African trypanosomiasis



African trypanosomiasis or sleeping sickness is a parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei. There are two types that infect humans, Trypanosoma brucei gambiense (T.b.g) and Trypanosoma brucei rhodesiense (T.b.r.). T.b.g causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.Initially, in the first stage of the disease, there are fevers, headaches, itchiness, and joint pains. This begins one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness and trouble sleeping. Diagnosis is via finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first and second stage disease.Prevention of severe disease involves screening the population at risk with blood tests for T.b.g. Treatment is easier when the disease is detected early and before neurological symptoms occur. Treatment of the first stage is with the medications pentamidine or suramin. Treatment of the second stage involves: eflornithine or a combination of nifurtimox and eflornithine for T.b.g. While melarsoprol works for both it is typically only used for T.b.r. due to serious side effects.The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. As of 2010 it caused around 9,000 deaths per year, down from 34,000 in 1990. An estimated 30,000 people are currently infected with 7000 new infections in 2012. More than 80% of these cases are in the Democratic Republic of the Congo. Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. Other animals, such as cows, may carry the disease and become infected.
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