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Vasculitis Information for patients and families Great Ormond Street Hospital
Vasculitis Information for patients and families Great Ormond Street Hospital

... ■ Steroids – Most severe cases of vasculitis will need treatment with steroids. It will often be started as injections of high doses of methylprednisolone in ‘pulses’ or blocks of treatment. After that the child will often need high doses of prednisolone as tablets or medicines, which we gradually r ...
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...  Certain high-risk conditions are compelling indications for other drug classes.  Most patients will require two or more antihypertensive drugs to achieve goal BP.  If BP is >20/10 mmHg above goal, initiate therapy with two agents, one usually should be a thiazide-type diuretic. ...
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Disease



A disease is a particular abnormal condition, a disorder of a structure or function, that affects part or all of an organism. The causal study of disease is called pathology. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by factors originally from an external source, such as infectious disease, or it may be caused by internal dysfunctions, such as autoimmune diseases. In humans, ""disease"" is often used more broadly to refer to any condition that causes pain, dysfunction, distress, social problems, or death to the person afflicted, or similar problems for those in contact with the person. In this broader sense, it sometimes includes injuries, disabilities, disorders, syndromes, infections, isolated symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts and for other purposes these may be considered distinguishable categories. Diseases usually affect people not only physically, but also emotionally, as contracting and living with a disease can alter one's perspective on life, and one's personality.Death due to disease is called death by natural causes. There are four main types of disease: pathogenic disease, deficiency disease, hereditary disease, and physiological disease. Diseases can also be classified as communicable and non-communicable. The deadliest disease in humans is ischemic heart disease (blood flow obstruction), followed by cerebrovascular disease and lower respiratory infections respectively.
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