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Lara Lehtoranta – Fetal heart and hemodynamics in diabetic
Lara Lehtoranta – Fetal heart and hemodynamics in diabetic

... throughout the second half of pregnancy, and transient mid-pregnancy cardiac dysfunction was observed. Increased myocardial cell turnover with cardiac hyperplasia and abnormal myocardial gene expression patterns were found. Increased placental vascular impedance and placental morphologic abnormaliti ...
Molecular analysis of putative genetic factors affecting BSE
Molecular analysis of putative genetic factors affecting BSE

... Information on the markers in the genotyping panel was provided to GeneSeek, who synthesised and tested the primers. Of the 150 markers in the panel, 146 worked successfully in their hands using the DNA samples provided. The 4 sires of large half-sib groups were genotyped and up between 53 and 124 a ...
Dynamics and control of DNA sequence amplification
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... operating conditions is required. However, in the absence of such a dynamic model, the operating conditions for PCR reactions are typically selected based on analysis of reaction thermodynamics, and, to a lesser extent, qualitative analysis of reaction kinetics. Reductions in cycle efficiency (eithe ...
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... method [21]. The primers for detecting TEM, SHV, CTX-M, CTX-M-3 and ISEcp1 genes are listed in Table 1. Detection of the blaTEM gene Detection of the blaTEM gene was done as reported earlier [17]. Briefly pair of primers matching the conserved sequences specific for TEM gene was used to amplify a sp ...
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Drugs and addiction: an introduction to epigenetics
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... Despite the atrocities that occurred when combining scientific notions with politics, scientists continued to objectively determine the material inside the cells that passed hereditary information. Earlier in the 20th century, prior to the predominance of Lysenkoism, Russian biochemist Phoebus Leven ...
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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
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... a spindle of fibers that extends from pole to pole. The asters, spindle, centrioles, and microtubules are collectively called the mitotic spindle (or mitotic apparatus). As prophase continues, a second group of microtubules grows out from the kinetochore to the poles of the cell. These kinetochore m ...
Genetics Heredity and Variation: *Heredity is the branch of science
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... *Variation is a science discovers why related individuals differ from each other. Mendel’s work:Gregor Mendel born in 1822 and in 1843 studding natural history in Vienna University. In 1856 studied the inheritance in pea by hybridization. The choice of pea has 5 advantages which are :1- Presence of ...
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Genetics Images/plasmids.jpg - KSU Faculty Member websites

... some plasmids like to insert themselves into the chromosome as "episomes" (what's an epi-phyte or an epi-dermis?), these still have a phase in which they are by themselves in the cytoplasm - and they are circular double=helices. How these circular helices get from cell to cell depends on whether the ...
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From mutation to gene

... under some condition where the gene product is nonessential, but there has to be another condition where the mutation prevents growth of the cells so you can select for complementation. In many cases this can be accomplished by using different media or growth temperatures. Temperature-sensistive mut ...
Bioinformatics (Warm Up + Cracking the Genetic Code)
Bioinformatics (Warm Up + Cracking the Genetic Code)

... Exmpl: Human genome is a string of length ≃3.200.000.000 However, (parts of) this sequence must be interpreted to get a biological meaning. • Find out the sequence of genomes and what does it tell us? Which parts code for proteins or enzymes? • Predict structure of RNA or proteins (and thus, determi ...
Identifying Pregnancy Deaths in the US: Vital Statistics and
Identifying Pregnancy Deaths in the US: Vital Statistics and

Antioxidants and Vitamins in Clinical Conditions
Antioxidants and Vitamins in Clinical Conditions

... structure and function of cell membranes, and are also damaging to membrane proteins such as receptors and enzymes (Katsiki and Manes 2009). Polyunsaturated fatty acids [PUFA] are particularly susceptible targets for ROS attack. The hydroxyl radical [HO•] is an important reactive moiety and initiato ...
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Cell-free fetal DNA

Cell-free fetal DNA (cffDNA) is fetal DNA circulating freely in the maternal blood stream. It can be sampled by venipuncture on the mother. Analysis of cffDNA provides a method of non-invasive prenatal diagnosis.cffDNA originates from the trophoblasts making up the placenta. It is estimated that 2-6% of the DNA in the maternal blood is fetal in origin. The fetal DNA is fragmented and makes its way into the maternal bloodstream via shedding of the placental microparticles into the maternal bloodstream (figure 1). Studies have shown that cffDNA can first be observed as early as 7 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses. cffDNA diminishes quickly after the birth of the baby, so that it is no longer detectable in the maternal blood approximately 2 hours after birth. cffDNA is significantly smaller than the maternal DNA in the bloodstream, with fragments approximately 200bp in size. Many protocols to extract the fetal DNA from the maternal plasma use its size to distinguish it from the maternal DNA.Studies have looked at, and some even optimized, protocols for testing non-compatible RhD factors, sex determination for X-linked genetic disorders and testing for single gene disorders. Current studies are now looking at determining aneuploidies in the developing fetus. These protocols can be done earlier than the current prenatal testing methods, and have no risk of spontaneous abortion, unlike current prenatal testing methods. Non-invasive prenatal diagnosis (NIPD) has been implemented in the UK and parts of the US; it has clear benefits above the standard tests of chorionic villi sample (CVS) and amniocentesis which have procedure-related miscarriage risks of about 1 in 100 pregnancies and 1 in 200 pregnancies, respectively.As a method of prenatal diagnosis, cell-free fetal DNA techniques share the same ethical and practical issues, such as the possibility of prenatal sex discernment and sex selection.
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