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T. caerulescens
T. caerulescens

... • T. caerulescens is a plant similar to A. thaliana but is a known to be a zinc hyperaccumulator • These two plants were used as subjects due to their similarity • Both plants were grown in 3 conditions, deficient, sufficient, and excess zinc, and then had their genes analyzed • DNA Microarray analy ...
Transcription Factors (from Wray et al Mol Biol Evol 20:1377)
Transcription Factors (from Wray et al Mol Biol Evol 20:1377)

... o Controls a phenotype  Individually  OR  Complexed with action of other genes • Size varies • Structural features vary • Encode for a protein(s) that is translated from a mRNA • Expression o Requires many associated factors ...
Chapter 14 Overview: The Flow of Genetic Information
Chapter 14 Overview: The Flow of Genetic Information

... of which is translated into a specific amino acid during protein synthesis.   The genetic code must have evolved very early in the history of life.  The genetic code is nearly universal, shared by organisms from the simplest bacteria to the most complex  plants and animals.  In laboratory experiment ...
GeneToProtein
GeneToProtein

... How Genes Work AP Biology ...
RNA Polymerases
RNA Polymerases

... regulation of their transcription. Some promoters such as the U6 small nuclear RNA (U6 snRNA ) and small RNA genes from the Epstein-Barr virus use only regulatory sequences upstream from their transcription start sites. The coding region of the U6 snRNA has a characteristic A box. However, this sequ ...
HUA1, a Regulator of Stamen and Carpel Identities
HUA1, a Regulator of Stamen and Carpel Identities

... In hua1-1, the major RNA species was 400 nucleotides longer than the wild-type HUA1 RNA (Figure 4), suggesting that the second intron was retained in most hua1-1 RNA. This major hua1-1 transcript was detected at 12% of the abundance of wild-type HUA1 RNA. Other hua1-1 RNA species of smaller sizes a ...
splicing
splicing

... • Individual genes can be silenced in mammals by RNAi that targets the gene’s control region, a promoter-associated transcript) rather than the coding region • Another silencing mechanism targets nuclear RNA as endogenous double-stranded siRNAs that contain a nuclear localization signal can enter th ...
Pseudogene function: regulation of gene expression
Pseudogene function: regulation of gene expression

... synthase (nNOS) is encoded by the NOS gene (now called the Lym-nNOS gene). The enzyme induces the production of nitrogen oxide (NO), an intracellular signaling molecule in the snail’s nervous system. One function of (NO) is the mediating of its feeding behavior. Korneev, Park, and O’Shea14 were prob ...
Molecular Cell Biology - Biomedical Informatics
Molecular Cell Biology - Biomedical Informatics

... One DNA strand is shown in green and the other in brown. H2A is yellow; H2B, red; H3, blue; H4, green. (b) Space-filling model shown from the side. DNA is shown in white; histones are colored as in (a). H2A, H2A′, H2B, H2B′, H3, and H4 indicate the positions of the respective histone N-terminal tail ...
Inherited variation at the epigenetic level: paramutation from the
Inherited variation at the epigenetic level: paramutation from the

... been, however, noted. As it is often the case, they were first considered somewhat secondary aspects, better left aside ‘for further studies.’ And at some point, they reached the front. One such event was the discovery by McClintock in the 1940s of genetic transposition in maize, a notion that was t ...
microRNA: microRNA
microRNA: microRNA

... deposited in the miRBase database (http://microrna.sanger.ac.uk/sequences/) ...
Chapter 25 RNA Metabolism
Chapter 25 RNA Metabolism

... energy-expensive pathway leading to protein synthesis, an ideal target for regulating gene expression.  The RNA polymerase binds to each promoter in very different efficiency.  Protein factors binding to DNA sequences close or distant to the promoters can promote (activator) or repress (repressor) ...
Body Axis Determination in Birds and Mammals
Body Axis Determination in Birds and Mammals

... Segment identity controlled by segment identity (aka homeotic, aka selector) genes. Discovered through homeotic mutations. This is a mutation that causes the transformation of one structure to another homologous structure. (Homologs have evolutionarily related ancestry—both derived from a common anc ...
An artifact in studies of gene regulation using β
An artifact in studies of gene regulation using β

... experiment by sequencing candidate plasmids. However, the frequency of occurrence of the artifact reduces the efficiency of detecting bona fide transcription factors and increases DNA sequencing costs. These problems can be avoided by choosing plasmids or other vectors that do not encode the a-peptide ...
Class: 12 Subject: Biology Topic: Principles of
Class: 12 Subject: Biology Topic: Principles of

... 1. Polytene chromosome was first observed by A. Stevens and Wilson B. Heitz and Batier C. Balbiani D. Khorana Ans. C 2. Which one is soluble RNA A. tRNA B. mRNA C. rRNA D. snRNA Ans. A Solution: tRNA’s are short-chain RNA molecules present in the cell (in at least 20 varieties, each variety apable o ...
Lecture2 Biol302 Spring2012
Lecture2 Biol302 Spring2012

... Insertion of 3 base pairs does not change the reading ...
M1 - Biochemistry Transcription III / mRNA Processing
M1 - Biochemistry Transcription III / mRNA Processing

... RNA Editing Changes the Sequence of mRNAs. Editing commonly occurs during mRNA maturation, & is carried out by enzymes that recognize a particular C (usually) that is hydrolytically deaminated to a U. An example is the apo B gene transcript that produces apoB100 normally in the liver, but is edited ...
17_Lecture_Presentation
17_Lecture_Presentation

... – Generates different forms of mRNA from identical pre-mRNA (increases number of proteins) – Expression of one gene gives rise to numerous proteins with similar and different functions – Increases number of proteins made from one gene (Figure 17-11 and Figure 17-12) ...
Exploring the Human Genome - Cayetano Heredia University
Exploring the Human Genome - Cayetano Heredia University

... Select Genes on Chromosome 10 Select chromosome ...
CHAPTER 17 FROM GENE TO PROTEIN
CHAPTER 17 FROM GENE TO PROTEIN

... molecules that function as enzymes. ° In some organisms, splicing occurs without proteins or additional RNA molecules. ° The intron RNA functions as a ribozyme and catalyzes its own excision. ° For example, in the protozoan Tetrahymena, self-splicing occurs in the production of ribosomal RNA (rRNA), ...
Tool box for studying gene function in neural development
Tool box for studying gene function in neural development

... • Slower, more difficult • more reliable ...
video slide
video slide

... Concept 18.3: Noncoding RNAs play multiple roles in controlling gene expression Only a small fraction of DNA codes for proteins, rRNA, and tRNA  A significant amount of the genome may be transcribed into noncoding RNAs  Noncoding RNAs regulate gene expression at two points: mRNA translation and c ...
pdf
pdf

... regions to consider, with 51 unique flanking genes. There are 6 super-regions with at least 99 bp overlapping with ultra-conserved elements. At least one of the flanking genes for each of these 6 super-regions is a transcription factor located 1–314 kb away (IRX3, IRX5, IRX6, HOXD13, DMRT1, DMRT3, F ...
Myriad myPath® Melanoma Technical Specifications
Myriad myPath® Melanoma Technical Specifications

... This gene expression signature is intended for the in vitro analysis of melanocytic neoplasms to aid in the diagnosis of the lesion as benign or malignant. This is an adjunctive assay and should be used in conjunction with clinical data and histopathological features. Summary and Explanation Melanom ...
When Is a Genome Project Finished?
When Is a Genome Project Finished?

... Match the correct term with each definition or select the best answer for each question. 1. A series of codons from a single strand of DNA sequence which can be "read" in three different ways, depending on whether one starts at the first nucleotide position, the second or third Reading Frame (RF) Al ...
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Short interspersed nuclear elements (SINEs)

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