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New weapons in the fight against HIV
New weapons in the fight against HIV

Alveolar macrophages (AMs)
Alveolar macrophages (AMs)

... • may not be for natural responses: - wide range protein antigens - acquired immunity seems independent of capsule serotype - anti-protein response to colonisation often dominant • protein antigens maybe crossprotective ...
Pharmacy 360 - Wishart Research Group
Pharmacy 360 - Wishart Research Group

... Delivery to Dendritic Cells • Dendritic Cells -‘sentries’ of the body • Eat pathogens and present their antigens to T cells • Secret cytokines to direct immune responses ...
PowerPoint Presentation - Overview of the Immune Response
PowerPoint Presentation - Overview of the Immune Response

... Adaptive Immunity to Parasites Different parasites elicit distinct adaptive immune responses Pathogenic protozoa have evolved to live within host cells. The principal defense mechanism against protozoa that survive within macrophages is cell mediated immunity, particularly macrophage activation by ...
DNA Testing Info
DNA Testing Info

... spider syndrome such changes have occurred in two sheep genes. (The prion protein gene in the case of scrapie and a fibroblast growth factor receptor gene in the case of spider.) DNA testing detects these single nucleotide changes. DNA testing, especially testing for scrapie susceptibility, is somet ...
Human Monoclonal Antibodies
Human Monoclonal Antibodies

Unit 3 - kehsscience.org
Unit 3 - kehsscience.org

... If a mutation occurs in a gamete, or sex cell (sperm or egg) then it will not affect the “parent organism”, but the mutation ___________ cause a defect in an offspring – again, because “bad proteins” could be made from the error in the “instructions” (DNA). Sometimes mutations can benefit an individ ...
August 2008
August 2008

... More and more genetically modified foods (GMFs) are entering the marketplace. In Europe all GMFs must be clearly labelled, but this is not the case in Canada. Should the Canadian food industry be forced to follow GMF labelling guidelines? State two reasons to support your answer. ...
Gene Expression
Gene Expression

... nucleus, into the cytoplasm. There, it binds to a ribosome, which reads the RNA strand and attaches a "T" nucleotide to the RNA "A" nucleotide, etc, until the entire RNA strand has been paired with nucleotides. This is translation. Then the RNA strand is taken away, taken apart, and its nucleotides ...
Downloadable PPT - Research To Practice
Downloadable PPT - Research To Practice

... received neoadjuvant trastuzumab with or without pertuzumab, with or without docetaxel. The focus in this particular analysis was targeting the immune checkpoints. Investigators evaluated a number of the immune-related genes, including PD-1, PD-L1 and others. A circle of activity that was observed h ...
Chapter 6 notes - s3.amazonaws.com
Chapter 6 notes - s3.amazonaws.com

... Genes and Proteins • Proteins and Traits Proteins act as chemical triggers for many of the processes within cells. Proteins help determine traits. ...
Module #
Module #

... Most pathogens are kept outside of the body by protective mechanisms such as tears, stomach acid and cilia  Pathogen enters the body: When there is an injury to tissue, bacteria or viruses can enter the tissue and cause an infection  “Innate” cells respond Cells, such as macrophages and dendritic ...
Definition of a Gene - Kaikoura High School
Definition of a Gene - Kaikoura High School

... used to calculate a paternity index (the probability of the evidence given that a particular man is the father versus he is not the father) • This is based on the frequency in the population of the alleles at that locus • In New Zealand there are databases for ...
File - LFHS AP Biology
File - LFHS AP Biology

... __ The triplet arrangement of codons and/or anticodons __ The control of transcription (Operon, etc.) __ Promoters __ The role of polymerase __ Intervening sequences in eukaryotic cells __ Factors involved in the release of mRNA from DNA __ 5' - 3' arrangement with attachment at -OH end A definition ...
Biology Keystone Review Packet Module 2 with Answers
Biology Keystone Review Packet Module 2 with Answers

... b. During the process of meiosis, haploid cells are formed. After fertilization, the diploid number of chromosomes is restored. c. The process of meiosis forms daughter cells which are genetically identical to their parent cells. d. The daughter cells formed during mitosis are genetically similar to ...
Module B Keystone Practice Problems answers File
Module B Keystone Practice Problems answers File

... b. During the process of meiosis, haploid cells are formed. After fertilization, the diploid number of chromosomes is restored. c. The process of meiosis forms daughter cells which are genetically identical to their parent cells. d. The daughter cells formed during mitosis are genetically similar to ...
Large-scale preparation of T4 endonuclease VII from
Large-scale preparation of T4 endonuclease VII from

1) From DNA to protein 2) Gene mutation
1) From DNA to protein 2) Gene mutation

... •  Wobble base pair •  The genetic code is not ambiguous—each codon specifies only one amino acid. •  The genetic code is nearly universal: The codons that specify amino acids are the same in all organisms. •  Exceptions: within mitochondria and chloroplasts, and in one group of protists, there are ...
Vaccine Case Study Answer Key File
Vaccine Case Study Answer Key File

File - MRS. WILSON Science
File - MRS. WILSON Science

... DNA provides the instructions needed by a cell to make proteins. But the instructions are not made directly into proteins. First, a DNA message is converted into RNA in a process called transcription. Then, the RNA message is converted into proteins in a process called translation. The relationship ...
TITLE of LESSON Immune system – Immune response: non
TITLE of LESSON Immune system – Immune response: non

... To foster grammar school level another micro-module can be used, that deals with antibody-antigen-representation on cell membrans. On this level, teachers can discuss recognitions signals and activation processes. ...
投影片 1 - National Cheng Kung University
投影片 1 - National Cheng Kung University

... the traditional, linear process of testing antigens one at a time has been revolutionized by genome-scale, parallel strategies for discovering candidate antigens — an approach commonly referred to as “reverse vaccinology”. ...
ILAR 46(2) - Laboratory Animal Boards Study Group
ILAR 46(2) - Laboratory Animal Boards Study Group

... cancer, addictions, allergies, and pregnancy to autoimmune diseases. It is also being used to produce biologically active materials such as polyclonal and monoclonal antibodies, antivenins, and antitoxins for treating a wide range of conditions. A large number of diseases exist for which there is no ...
Lesson Objectives: You must be comfortable doing these items:
Lesson Objectives: You must be comfortable doing these items:

... Effects of Mutations Many mutations have no effect on the proteins they encode. These mutations are considered neutral. Occasionally, a mutation may make a protein even better than it was before. Or the protein might help the organism adapt to a new environment. These mutations are considered benefi ...
video slide
video slide

... and leads to activation of 3 p53. Activated p53 promotes transcription of the gene for a protein that inhibits the cell cycle. The resulting suppression of cell division ensures that the damaged DNA is not replicated. Mutations causing deficiencies in any pathway component can contribute to the deve ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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