YOU ARE WHAT YOU ABSORB YOU ARE NOT WHAT YOU EAT
... Collagen is the most abundant protein in the human body. It gives the shape and support to all tissues including the skin. ...
... Collagen is the most abundant protein in the human body. It gives the shape and support to all tissues including the skin. ...
- Journal of Hepatology
... indication of an increased turnover of phosphatidylcholine and phosphatidylethanolamine species in the liver, thus releasing free fatty acids through the action of phospholipases A1 and A2. These fatty acids, if not catabolized by b-oxidation, will be stored in the liver as triacylglycerols. This is ...
... indication of an increased turnover of phosphatidylcholine and phosphatidylethanolamine species in the liver, thus releasing free fatty acids through the action of phospholipases A1 and A2. These fatty acids, if not catabolized by b-oxidation, will be stored in the liver as triacylglycerols. This is ...
1 A multi-platform metabolomics approach identifies novel
... In total we identified 49 metabolites that were significantly different between BV and N (unpaired t-test, Benjamini-Hochberg p < 0.01, Table S2). Nineteen of these have not been reported as differential in the literature, and 12 could not be identified. We determined the odds ratio (OR) for BV base ...
... In total we identified 49 metabolites that were significantly different between BV and N (unpaired t-test, Benjamini-Hochberg p < 0.01, Table S2). Nineteen of these have not been reported as differential in the literature, and 12 could not be identified. We determined the odds ratio (OR) for BV base ...
Chapter 1 - Research Explorer
... treatment interventions. Treatment is in general aimed to reduce metabolic decompensation as well as to prevent neurological damage and developmental delay. The phenotypical presentation of the organic acidemias is broad. Isovaleric acidemia (IVA), which is the result of the defective isovaleryl-CoA ...
... treatment interventions. Treatment is in general aimed to reduce metabolic decompensation as well as to prevent neurological damage and developmental delay. The phenotypical presentation of the organic acidemias is broad. Isovaleric acidemia (IVA), which is the result of the defective isovaleryl-CoA ...
Organic biomarkers in deep-sea regions affected
... and neutral amino acids are less labile than pigments and unsaturated fatty acids, but like them, they are utilized as indicators of labile material (Mayer et al., 1995; Lee et al., 2004). The use of this combination of biomarkers will allow for us to study the effects of sediment reworking by trawl ...
... and neutral amino acids are less labile than pigments and unsaturated fatty acids, but like them, they are utilized as indicators of labile material (Mayer et al., 1995; Lee et al., 2004). The use of this combination of biomarkers will allow for us to study the effects of sediment reworking by trawl ...
Circulating Folate, Vitamin B12, Homocysteine, Vitamin B12
... hence, it was adjusted for exact age and the study center where the recruiting general practice was based (ninelevel variable). Pairwise correlations between circulating vitamin and metabolite concentrations (and with PSA level) in controls were measured by Spearman's rank correlation coefficient. G ...
... hence, it was adjusted for exact age and the study center where the recruiting general practice was based (ninelevel variable). Pairwise correlations between circulating vitamin and metabolite concentrations (and with PSA level) in controls were measured by Spearman's rank correlation coefficient. G ...
Download: 7.2 MB PDF
... pioneering a systems approach that supports healthcare providers in the personalized treatment and prevention of chronic disease. Chronic diseases are often complex and Genova’s system-based testing helps physicians develop targeted treatments for their patients. Easy-to-read color graphic reports s ...
... pioneering a systems approach that supports healthcare providers in the personalized treatment and prevention of chronic disease. Chronic diseases are often complex and Genova’s system-based testing helps physicians develop targeted treatments for their patients. Easy-to-read color graphic reports s ...
Document
... • Clinical use of biomarkers for early diagnosis of AKI is promising but awaits prospective clinical trials . • While several trials have demonstrated the ability to reduce AKI in randomized trials only hANP has demonstrated ability to reduce AKI and decrease risk of CKD and Dialysis ...
... • Clinical use of biomarkers for early diagnosis of AKI is promising but awaits prospective clinical trials . • While several trials have demonstrated the ability to reduce AKI in randomized trials only hANP has demonstrated ability to reduce AKI and decrease risk of CKD and Dialysis ...
Secrets from the microbiome: molecular biology meets microbiology
... Secrets from the microbiome: molecular biology meets microbiology meets histopathology….meets clinical biochemistry Abstract The microbiome is the collective term used to describe the bacteria, viruses, fungi and archaea that reside on and in the human body. The majority of these organisms are found ...
... Secrets from the microbiome: molecular biology meets microbiology meets histopathology….meets clinical biochemistry Abstract The microbiome is the collective term used to describe the bacteria, viruses, fungi and archaea that reside on and in the human body. The majority of these organisms are found ...
Chronic Liver Diseases
... coronary syndromes, can produce chest pain at rest, lead to specific changes in tile electrocardiogram, and a mild or severe release of enzymes and proteins into blood. ...
... coronary syndromes, can produce chest pain at rest, lead to specific changes in tile electrocardiogram, and a mild or severe release of enzymes and proteins into blood. ...
Observations on the role of nuclear medicine in molecular imaging
... glucose metabolism. One PET agent is 11Cpalmitate which behaves identically to natural fatty acids in uptake and metabolism in the myocardium. Fatty acids may also be labeled with 123I and used for the same purpose but with SPECT. One such agent is labeled iodophenypentadecanoic acid (i.e., 123I-IPP ...
... glucose metabolism. One PET agent is 11Cpalmitate which behaves identically to natural fatty acids in uptake and metabolism in the myocardium. Fatty acids may also be labeled with 123I and used for the same purpose but with SPECT. One such agent is labeled iodophenypentadecanoic acid (i.e., 123I-IPP ...
Increased Protein and Lipid Oxidative Damage in
... and neuroprostanes in plasma; however, data presented in this study showed increased levels of protein-bound HNE in the mitochondria isolated from lymphocyte of AD and shows a trend toward negative correlation to the MMSE score, consistent with our findings reported in the present study. In the plas ...
... and neuroprostanes in plasma; however, data presented in this study showed increased levels of protein-bound HNE in the mitochondria isolated from lymphocyte of AD and shows a trend toward negative correlation to the MMSE score, consistent with our findings reported in the present study. In the plas ...
Apresentação do PowerPoint
... -Detection of small increases in oxidant/radical production improved probes/spin traps under development (this symposium) -Monitoring GSSG/2 GSH levels (Schafer & Beuttner FRBM 30, 1191) may not reflect localized redox unbalance (Go et al. JBC 279, 5837) -Characterizing/quantifying products/radicals ...
... -Detection of small increases in oxidant/radical production improved probes/spin traps under development (this symposium) -Monitoring GSSG/2 GSH levels (Schafer & Beuttner FRBM 30, 1191) may not reflect localized redox unbalance (Go et al. JBC 279, 5837) -Characterizing/quantifying products/radicals ...
Markers of renal function tests (PDF Available)
... the routine methods gave borderline values for the index of proteinuria [30]. During pregnancy proteinuria assay in 24 hour urine sample is performed. One of the investigations for proteinuria is semi-quantitative dipstick urinalysis as this method is relatively low cost and easily ...
... the routine methods gave borderline values for the index of proteinuria [30]. During pregnancy proteinuria assay in 24 hour urine sample is performed. One of the investigations for proteinuria is semi-quantitative dipstick urinalysis as this method is relatively low cost and easily ...
Early diagnosis
... Identification of disease type by discovery of disease-related genes and analysis of profiles. Support for deciding on an optimum therapeutic policy in combination with clinical information. For infectious diseases, diagnosis of the presence or absence of infection by ...
... Identification of disease type by discovery of disease-related genes and analysis of profiles. Support for deciding on an optimum therapeutic policy in combination with clinical information. For infectious diseases, diagnosis of the presence or absence of infection by ...
Ingenuity Pathway Analysis of metabolomics data including cross
... diabetic mouse, one of the most extensively studied animal models of severe type 2 diabetes. To assist with cross platform integration we have used IPA-Metabolomics™ analysis. IPA-Metabolomics is powered by the Ingenuity Knowledge Base, a repository of molecular interactions, regulatory events, sign ...
... diabetic mouse, one of the most extensively studied animal models of severe type 2 diabetes. To assist with cross platform integration we have used IPA-Metabolomics™ analysis. IPA-Metabolomics is powered by the Ingenuity Knowledge Base, a repository of molecular interactions, regulatory events, sign ...
Systems Biology Investigation to Discover Metabolic Biomarkers of
... Background: Drug-induced hepatotoxicity is one of the major reasons for drug recall and hence it is of major concern to the FDA and consumers. Overdose of acetaminophen (APAP) can cause acute hepatic injury. The current clinical biomarkers of liver injury are insufficient in predicting the extent of ...
... Background: Drug-induced hepatotoxicity is one of the major reasons for drug recall and hence it is of major concern to the FDA and consumers. Overdose of acetaminophen (APAP) can cause acute hepatic injury. The current clinical biomarkers of liver injury are insufficient in predicting the extent of ...
Spain - Eurocare
... The preliminary results of our study evidence for first time the presence of EtG and EtS in meconium. Further investigations are ongoing to verify the use of these two ethanol metabolites as alternative biomarkers of chronic in utero exposure to alcohol. ...
... The preliminary results of our study evidence for first time the presence of EtG and EtS in meconium. Further investigations are ongoing to verify the use of these two ethanol metabolites as alternative biomarkers of chronic in utero exposure to alcohol. ...
Metabolomic Profiling Identifies Biomarkers Associated
... Use these new assays in a representative cohort not used to identify the candidate biomarkers to test their suitability: – To predict incident type 2 diabetes alone – For use in models with other metabolites and metabolic parameters for: l The prediction of type 2 diabetes l Monitoring interventi ...
... Use these new assays in a representative cohort not used to identify the candidate biomarkers to test their suitability: – To predict incident type 2 diabetes alone – For use in models with other metabolites and metabolic parameters for: l The prediction of type 2 diabetes l Monitoring interventi ...
Comparative Study of Serum lactic Acid, Lactate
... It has been rep orted that LDH activity is inhibited in the postischemic myocardium, which is associated with p oor glucose oxidation and impaired my ocardial p erformance [10]. A st udy conducted on rat reported that a three fold increase in LDH content in rat heart comp ared with liver, the author ...
... It has been rep orted that LDH activity is inhibited in the postischemic myocardium, which is associated with p oor glucose oxidation and impaired my ocardial p erformance [10]. A st udy conducted on rat reported that a three fold increase in LDH content in rat heart comp ared with liver, the author ...
Metabolomics Research Core
... characteristics of exposure, and receive training in metabolomics research. ...
... characteristics of exposure, and receive training in metabolomics research. ...
Fluorodopa F-18
... F-FDOPA may perform particularly well in patients with PGL who do not carry a SDHB mutation (17). (However, in pts with metastatic pheochromocytoma or PGL, 18F-FDG or 18FFluorodopamine may perform better than FDOPA (17, 18)). In patients with MTC and elevated calcitonin levels, 18F-FDOPA PET/CT may ...
... F-FDOPA may perform particularly well in patients with PGL who do not carry a SDHB mutation (17). (However, in pts with metastatic pheochromocytoma or PGL, 18F-FDG or 18FFluorodopamine may perform better than FDOPA (17, 18)). In patients with MTC and elevated calcitonin levels, 18F-FDOPA PET/CT may ...
DOC - Investor Relations
... patients with multi-vessel disease. It is important to note that, with a 110 minute half-life, flurpiridaz F 18 can be used in conjunction with treadmill exercise, which is not feasible with other currently available PET tracers for MPI. About PET and MPI PET imaging or a PET scan is a type of nucle ...
... patients with multi-vessel disease. It is important to note that, with a 110 minute half-life, flurpiridaz F 18 can be used in conjunction with treadmill exercise, which is not feasible with other currently available PET tracers for MPI. About PET and MPI PET imaging or a PET scan is a type of nucle ...