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Osteogenesis imperfecta, type II
Osteogenesis imperfecta, type II

... association of the protein strands  All of these changes prevent the normal production of mature type I collagen  which results in this severe condition, type II osteogenesis imperfecta ...
msb145487-sup-0021-Legends
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... each group in each brain section (in black) was compared with the transcriptome median (shared by both groups, in green). The zoom-in view shows an elevation of gene expression of Group 1 genes in the corpus callosum, where Group 2 genes were down-regulated. The overall expression of Group 2 genes w ...
Setting up a transformation--how will the competent cells be treated?
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... the cell as synthetic RNAs, replicating viruses or may be transcribed from nuclear genes. – These are recognized and processed into small interfering RNAs by Dicer. – The duplex siRNAs are passed to RISC (RNAinduced silencing complex) – The complex becomes activated by unwinding of the duplex. – Act ...
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Non-Mendelian Genetics
Non-Mendelian Genetics

... Coat color in cats is a codominant trait. Cats can be black, yellow or calico. A calico cat has black and yellow splotches. In order to be calico. the cat must have an allele for the black color and an allele for the yellow color. Show a cross between a calico cat and a yellow cat. What are the pos ...
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... Genomic DNA is extracted from blood, lymph node, bone marrow, or other tissue types (formalin-fixed or fresh) and the rearranged immunoglobulin heavy (and/or light) chain genes are amplified by PCR using a multiplex primer method based on the BIOMED-2 strategy (1,2). Precise fragment sizing of the a ...
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1 - Webcourse

... 4. Htfoot (h), obese (o), and waved (wa) are recessive genes found in mice. A trihybrid whose parents were unknown was testcrossed, producing the following progeny: hotfoot, obese, waved hotfoot, obese waved obese wild-type hotfoot, waved obese, waved hotfoot TOTAL ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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