Beyond Co-expression: Gene Network Inference
... concert with other TF’s. Synergistic effects • Clustering: – a motif may occur in more than one cluster, because it may give rise to different expression patterns depending on its interaction partners. – several motifs may occur in the same cluster. ...
... concert with other TF’s. Synergistic effects • Clustering: – a motif may occur in more than one cluster, because it may give rise to different expression patterns depending on its interaction partners. – several motifs may occur in the same cluster. ...
Leukaemia Section t(3;21)(q26;q22) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... AML1-EVI1: 180 kDa; breakpoint after exon 5 or 6 in AML1, at the very 5' end of EVI1 → translocation protein includes N-term AML1 with the Runt domain and most of the gene EVI1, from the second untranslated exon to C-term, which includes the 2 zinc fingers. ...
... AML1-EVI1: 180 kDa; breakpoint after exon 5 or 6 in AML1, at the very 5' end of EVI1 → translocation protein includes N-term AML1 with the Runt domain and most of the gene EVI1, from the second untranslated exon to C-term, which includes the 2 zinc fingers. ...
DOCX 51 KB - Office of the Gene Technology Regulator
... thale cress (Arabidopsis thaliana) and maize (Zea mays), a moss (Physcomitrella patens) and a yeast (Saccharomyces cerevisiae). The introduced genes encode proteins that are intended to enable normal plant growth with reduced amounts of water (drought tolerance) either by regulating gene expression ...
... thale cress (Arabidopsis thaliana) and maize (Zea mays), a moss (Physcomitrella patens) and a yeast (Saccharomyces cerevisiae). The introduced genes encode proteins that are intended to enable normal plant growth with reduced amounts of water (drought tolerance) either by regulating gene expression ...
Data Analysis for High-Throughput Sequencing
... change together – one PC explains 95% • In most preparations the initiation site biases change by a few percent • In a few preparations the initiation site biases change by ~20%-30% • This may have consequences for representation in ChIP-Seq assays ...
... change together – one PC explains 95% • In most preparations the initiation site biases change by a few percent • In a few preparations the initiation site biases change by ~20%-30% • This may have consequences for representation in ChIP-Seq assays ...
CHAPTER 6
... Mendelian trait, the law of segregation tells us that a heterozygote passes one allele for a given gene to an offspring, but not both. In contrast, if a parent has a mixed population of mitochondria (e.g., some carrying a mutant gene and some carrying a normal gene), that parent could pass both typ ...
... Mendelian trait, the law of segregation tells us that a heterozygote passes one allele for a given gene to an offspring, but not both. In contrast, if a parent has a mixed population of mitochondria (e.g., some carrying a mutant gene and some carrying a normal gene), that parent could pass both typ ...
When Is Hub Gene Selection Better than
... – e.g. nervous system development (Bonferroni corrected pvalue =2.1e-6), – neuron differentiation (p=7.6e-5), – anatomical structure development (p=0.00013), – cell development (p=0.00024), – generation of neurons (p=0.00038), – neurogenesis (p=0.00052), cell differentiation (p=0.00057). ...
... – e.g. nervous system development (Bonferroni corrected pvalue =2.1e-6), – neuron differentiation (p=7.6e-5), – anatomical structure development (p=0.00013), – cell development (p=0.00024), – generation of neurons (p=0.00038), – neurogenesis (p=0.00052), cell differentiation (p=0.00057). ...
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... showing the amplification of the Ty elements described in the text: in lane 1 San1 wild type, in lane 2 Susu7 at 100% survival and in lane 3 the colony with the merged chromosome V. Lanes 1, 2, 3 on the left refer to YERCTy1-1 while lanes 1, 2, 3 on the right refer to YERCTy1-2. The distance between ...
... showing the amplification of the Ty elements described in the text: in lane 1 San1 wild type, in lane 2 Susu7 at 100% survival and in lane 3 the colony with the merged chromosome V. Lanes 1, 2, 3 on the left refer to YERCTy1-1 while lanes 1, 2, 3 on the right refer to YERCTy1-2. The distance between ...
The α-globin gene cluster: genetics and disorders
... other recombination events. Therefore the total number of α-globin genes an person may have can range from 0 to as many as 7 or 8.5,6 These observations illustrate one example of human genetic diversity. Whereas the α2- and α1-globin genes encode identical α-globin chains of 141 amino acid residues, ...
... other recombination events. Therefore the total number of α-globin genes an person may have can range from 0 to as many as 7 or 8.5,6 These observations illustrate one example of human genetic diversity. Whereas the α2- and α1-globin genes encode identical α-globin chains of 141 amino acid residues, ...
Identifying Stage-Specific Genes by Combining
... The Derisi dataset includes results generated from two different procedures to synchronize P. falciparum. We identified genes that were strongly up-regulated in the sporozoite and gametocyte stages using data generated from both synchronization procedures. As shown in Tables 1 and 2, both synchroniz ...
... The Derisi dataset includes results generated from two different procedures to synchronize P. falciparum. We identified genes that were strongly up-regulated in the sporozoite and gametocyte stages using data generated from both synchronization procedures. As shown in Tables 1 and 2, both synchroniz ...
Teacher notes and student sheets
... (d) Some newspapers reported that a gene for anti-social behaviour had been identified. Do the results of the research study support this idea or not? Explain your answer. The study shows that possessing a specific variant of a gene increases the likelihood of affiliation with delinquent individua ...
... (d) Some newspapers reported that a gene for anti-social behaviour had been identified. Do the results of the research study support this idea or not? Explain your answer. The study shows that possessing a specific variant of a gene increases the likelihood of affiliation with delinquent individua ...
Fulltext: english, pdf
... Development of clinically relevant primary tumours is expected to originate only from progenitor cells that have developed important characteristics of cancerous phenotype prior to malignant transformation. Key mutation can be detected in cells of most well-researched sporadic tumours. It is not nec ...
... Development of clinically relevant primary tumours is expected to originate only from progenitor cells that have developed important characteristics of cancerous phenotype prior to malignant transformation. Key mutation can be detected in cells of most well-researched sporadic tumours. It is not nec ...
ALE 11. Genetics of Viruses, Recombinant DNA Technology, Gene
... 6. Retroviruses such as HIV use reverse transcriptase to turn the virus’s genetic material, RNA, into DNA. Explain how reverse transcriptase is used in genetic engineering to make genes of interest. ...
... 6. Retroviruses such as HIV use reverse transcriptase to turn the virus’s genetic material, RNA, into DNA. Explain how reverse transcriptase is used in genetic engineering to make genes of interest. ...
Ember, társadalom és környezet
... images such as fearful faces. Monitoring activity in key brain regions such as the amygdale (the brain center for emotions), the seat of fear, they found that the amygdalas of subjects with the “warrior” variant were hyper-responsive to such images. This sensitivity suggests that these individuals h ...
... images such as fearful faces. Monitoring activity in key brain regions such as the amygdale (the brain center for emotions), the seat of fear, they found that the amygdalas of subjects with the “warrior” variant were hyper-responsive to such images. This sensitivity suggests that these individuals h ...
SICB 2014 Annual Meeting Abstracts
... gene regulatory regions through a highly conserved DNA binding domain (DBD) composed of three C−terminal C2H2 zinc fingers (KLF−DBD). Members of the Klf gene family influence transcription via interactions with other transcription factors, cofactors, chromatin remodeling factors, and transcriptional ...
... gene regulatory regions through a highly conserved DNA binding domain (DBD) composed of three C−terminal C2H2 zinc fingers (KLF−DBD). Members of the Klf gene family influence transcription via interactions with other transcription factors, cofactors, chromatin remodeling factors, and transcriptional ...
Allele- and parent-of-origin-specific effects on expression of the
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
Genetic Disorder Template
... Summary Cystic Fibrosis mainly affects 2 of our many systems: -Respiratory, and -Digestive In these systems our airways, lungs (respiratory), stomach, colon, and intestines (digestive) These organs are affected by this disease because Cystic Fibrosis causes a change in the properties of the m ...
... Summary Cystic Fibrosis mainly affects 2 of our many systems: -Respiratory, and -Digestive In these systems our airways, lungs (respiratory), stomach, colon, and intestines (digestive) These organs are affected by this disease because Cystic Fibrosis causes a change in the properties of the m ...
Genetic-Exchange - Microbiology and Immunology Online
... • Antibiotic resistance • Exponential increase under selective pressure ...
... • Antibiotic resistance • Exponential increase under selective pressure ...
Invited Review: Sex-based differences in gene expression
... some of these genes, including those for stature, suppression of gonadoblastoma, and prevention of the Turner syndrome phenotype (39, 40, 57). Differences in histocompatibility can also be ascribed to Y-linked genes. The SMCY gene encodes the HY antigen, which is ubiquitously expressed in male tissu ...
... some of these genes, including those for stature, suppression of gonadoblastoma, and prevention of the Turner syndrome phenotype (39, 40, 57). Differences in histocompatibility can also be ascribed to Y-linked genes. The SMCY gene encodes the HY antigen, which is ubiquitously expressed in male tissu ...
Introduction to Microarray Analysis (Section D1)
... molecule (target) to bind specifically to, or hybridize to, the DNA template (probe) from which it originated. This mechanism acts as both an "on/off" switch to control which genes are expressed in a cell as well as a "volume control" that increases or decreases the level of expression of particular ...
... molecule (target) to bind specifically to, or hybridize to, the DNA template (probe) from which it originated. This mechanism acts as both an "on/off" switch to control which genes are expressed in a cell as well as a "volume control" that increases or decreases the level of expression of particular ...
Recombinant DNA technology
... Most widely applied use of homologous recombination in ES cells has been the generation of knockout mice - Usually all or part of the protein coding sequences is deleted or an insertion is made into a exon encoding an essential domain - - the targeting vector is introduced into ES cells by subjectin ...
... Most widely applied use of homologous recombination in ES cells has been the generation of knockout mice - Usually all or part of the protein coding sequences is deleted or an insertion is made into a exon encoding an essential domain - - the targeting vector is introduced into ES cells by subjectin ...
Brooker Chapter 17
... of genes with more diverse functions Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... of genes with more diverse functions Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
Genetic Techniques for Biological Research Chapter7
... function of the gene productcan be obtained, analysis of transcript expression patterns, and subcellular location of the gene product. If available, several mutant alleles should be cloned and analyzed. Mutation analysis, the detailed characterization of a number of mutant alleles, is an essential f ...
... function of the gene productcan be obtained, analysis of transcript expression patterns, and subcellular location of the gene product. If available, several mutant alleles should be cloned and analyzed. Mutation analysis, the detailed characterization of a number of mutant alleles, is an essential f ...
Leukaemia Section del(13q) in myeloid malignancies Atlas of Genetics and Cytogenetics
... cell-cycle control. The activity of pRb depends on its degree of phosphorylation. The hypophosphorylated form of pRb maintains cell in quiescence by its ability to bind to transcription factors of the E2F family, whereas during the G1-S phase the hyperphosphorylated form of pRb does not bind the E2F ...
... cell-cycle control. The activity of pRb depends on its degree of phosphorylation. The hypophosphorylated form of pRb maintains cell in quiescence by its ability to bind to transcription factors of the E2F family, whereas during the G1-S phase the hyperphosphorylated form of pRb does not bind the E2F ...
The Genetics of Sensorineural Hearing Loss (SNHL)
... structures called chromosomes which are found in every cell in the body. Most people have 23 pairs of chromosomes (46 in total). One of each pair comes from the mother and the other from the father. Chromosomes are numbered 1 (the largest pair) to 22 (the smallest pair); the 23rd pair are called sex ...
... structures called chromosomes which are found in every cell in the body. Most people have 23 pairs of chromosomes (46 in total). One of each pair comes from the mother and the other from the father. Chromosomes are numbered 1 (the largest pair) to 22 (the smallest pair); the 23rd pair are called sex ...