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The Human Genome Project
The Human Genome Project

... Bioinformatics combines molecular biology with information science. It is critical to studying and understanding the human genome. ...
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Slide 1

... of an organism; DNA is located in cells. • Chromosomes – Structures that contain compacted DNA molecules; humans have 46 chromosomes and every species has it own unique number. • Double helix – The physical “twisted ladder” structure of DNA. • DNA – Deoxyribose nucleic acid; double helix shaped mole ...
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... the ancient artists were correct in tending to place the right testicle higher, they were wrong in so far as they also tended to make the Iower testicle the larger: we may postulate that they were also using the common-sense view that the heavier ought to be Iower. Although Winckelmann’s observation ...
PowerPoint PDF Printout
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... Process by which a DNA sequence is copied to produce a complementary mRNA strand. In other words, it is the transfer of genetic information from DNA into RNA. Like replication, but making RNA. Beginning of the process that ultimately leads to the translation of the genetic code (via mRNA) into a pro ...
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Lambda Gene Family

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... DNA profiling is the use of molecular genetic methods to determine the exact genotype of a DNA sample in a way that can basically distinguish one human being from another The unique genotype of each sample is called a DNA profile. ...
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... DNA profiling is the use of molecular genetic methods to determine the exact genotype of a DNA sample in a way that can basically distinguish one human being from another The unique genotype of each sample is called a DNA profile. ...
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... single stranded RNA copy of the gene. RNA, like DNA, is composed of a linear sequence of nucleotides, but the sugar– phosphate backbone consists of ribose sugar instead of deoxyribose and the base thymine is replaced by a very similar base uracil. Before the RNA molecule leaves the nucleus it underg ...
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Structure of the human DNA repair gene HAP1 and its localisation to

... mammalian species. We have cloned the HAP1 gene and determined its complete nucleotide sequence. The site of transcription initiation has been mapped to 452 bp upstream of the ATG initiation codon in the genomic DNA. The HAP1 gene consists of five exons and is unusually small (less than 2.6 kb from ...
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... 7. An amino acid–tRNA complex forms, which then travels to a ribosome to “transfer” its amino acid during protein synthesis. B. The Role of Ribosomal RNA 1. Ribosomal RNA (rRNA) is produced from a DNA template in the nucleolus of the nucleus. 2. The rRNA is packaged with a variety of proteins into r ...
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... Bioinformatics is the use of computers and informatics to analyze biological data (DNA, proteins). Bioinformatics has witnessed many developments in the past 10 years so that it can be applied nowadays in several fields like medicine, genomics, ...
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MOLECULAR BASIS OF INHERITANCE
MOLECULAR BASIS OF INHERITANCE

... pneumonia has proved conclusively that DNA is the genetic material by Avery et. al., a. DNA from S strain + R-strain alive + DNase b. DNA from S strain + Heat killed R-strain + DNase c. DNA from S strain + R-strain alive + RNase d. Denaturized DNA from S strain + R-strain + ...
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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell (Russell 2010 p. 217 & 230). Epigenetic modifications are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence (Russell 2010 p. 475). Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis (Russell 2010 p. 597). The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays (Laird 2010) and.
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