Cystic Fibrosis
... minerals in the blood. The imbalance may cause a heat emergency. CF also can cause infertility (mostly in men). The symptoms and severity of CF vary from person to person. Some people with CF have serious lung and digestive problems. Other people have more mild disease that doesn't show up until the ...
... minerals in the blood. The imbalance may cause a heat emergency. CF also can cause infertility (mostly in men). The symptoms and severity of CF vary from person to person. Some people with CF have serious lung and digestive problems. Other people have more mild disease that doesn't show up until the ...
Characterization of the first cultured representative of
... movies. Illumina sequencing was performed on a MiSeq platform with 2 × 150 cycles. The paired-end library contained inserts of an average insert size of 500 bp and delivered 1.8 million reads. A draft long read genome assembly named L21-Fru-AB-SP4_HGAP_5SC_std_np was created using the ‘RS_HGAP_Assem ...
... movies. Illumina sequencing was performed on a MiSeq platform with 2 × 150 cycles. The paired-end library contained inserts of an average insert size of 500 bp and delivered 1.8 million reads. A draft long read genome assembly named L21-Fru-AB-SP4_HGAP_5SC_std_np was created using the ‘RS_HGAP_Assem ...
Cancer Prone Disease Section Fanconi anaemia Atlas of Genetics and Cytogenetics
... Hypersensitivity to the clastogenic effect of DNA cross-linking agents (increased rate of breaks and radial figures); diepoxybutane, mitomycin C, or mechlorethamine hydrochlorid are used for diagnosis. ...
... Hypersensitivity to the clastogenic effect of DNA cross-linking agents (increased rate of breaks and radial figures); diepoxybutane, mitomycin C, or mechlorethamine hydrochlorid are used for diagnosis. ...
Insertion (sufB) in the anticodon loop or base substitution (sufC) in
... mechanism behind the temperature sensitivity of the double mutants is not known. However, the combined strength of two frameshift suppressors may be too much for the cell to sustain especially if both mutations affect the same molecule mediating the frameshifting ability. The sufA6 and sufB2 are dom ...
... mechanism behind the temperature sensitivity of the double mutants is not known. However, the combined strength of two frameshift suppressors may be too much for the cell to sustain especially if both mutations affect the same molecule mediating the frameshifting ability. The sufA6 and sufB2 are dom ...
Genetic association between the PRKCH gene encoding protein
... 18p, and Xq) overlapped ⱖ2 genome screens (8); however, other than the HLA region, no obvious consensus regarding which chromosomal regions would be most likely to contain RA susceptibility genes was obtained. This is consistent with other complex genetic disorders such as type 1 diabetes mellitus ( ...
... 18p, and Xq) overlapped ⱖ2 genome screens (8); however, other than the HLA region, no obvious consensus regarding which chromosomal regions would be most likely to contain RA susceptibility genes was obtained. This is consistent with other complex genetic disorders such as type 1 diabetes mellitus ( ...
Determining the cause of patchwork HBA1 and HBA2 genes
... α121 patchwork allele due to its alternating α1, α2, and α1 sequences (Figure 2). PCR sequencing of the HBA2 gene of patient AP was negative for any mutations (data not shown). Separately, in the course of routine HBA1 and HBA2 gene screening of asymptomatic individuals with borderline low normal MC ...
... α121 patchwork allele due to its alternating α1, α2, and α1 sequences (Figure 2). PCR sequencing of the HBA2 gene of patient AP was negative for any mutations (data not shown). Separately, in the course of routine HBA1 and HBA2 gene screening of asymptomatic individuals with borderline low normal MC ...
poor homologous synapsis 1 a novel gene required for homologous
... Detection of SNPs can be done without gels: highly automated/high throughput and/or highly parallel (simultaneous scoring of MANY markers) ...
... Detection of SNPs can be done without gels: highly automated/high throughput and/or highly parallel (simultaneous scoring of MANY markers) ...
Figures and figure supplements
... cells. Switches are labeled with the numbers 1 and 2. In pedigree A, onset of GFP expression (depicted as yellow) was detected in a large-budded cell (1). At the same time, GFP also appeared in the daughter cell that arose from the previous cell division (2). Due to the assymetry of switch 1 (only t ...
... cells. Switches are labeled with the numbers 1 and 2. In pedigree A, onset of GFP expression (depicted as yellow) was detected in a large-budded cell (1). At the same time, GFP also appeared in the daughter cell that arose from the previous cell division (2). Due to the assymetry of switch 1 (only t ...
DNA phosphorothioation inStreptomyces lividans: mutational
... Most of the commonly found structural changes in DNA are due to methylation of selected bases. In some viral DNAs, certain bases may be hydroxymethylated or gluco- ...
... Most of the commonly found structural changes in DNA are due to methylation of selected bases. In some viral DNAs, certain bases may be hydroxymethylated or gluco- ...
BBSI Final Report
... aureus; all carrying genes related to the virulence of the species. Mobility has been demonstrated for SaPI1, the first PI identified in S. aureus, and this transfer requires the helper bacteriophage 80. SaPI is transferred to other cells via transducing particles that are 1/3 the size of the norma ...
... aureus; all carrying genes related to the virulence of the species. Mobility has been demonstrated for SaPI1, the first PI identified in S. aureus, and this transfer requires the helper bacteriophage 80. SaPI is transferred to other cells via transducing particles that are 1/3 the size of the norma ...
Mapping strategies for sequence reads (with focus on RNA-seq)
... uires a set of known junctions from the reference ond, the QPALMA pipeline’s initial mapping phase ...
... uires a set of known junctions from the reference ond, the QPALMA pipeline’s initial mapping phase ...
Regulation of secondary metabolism in streptomycetes
... secondary metabolic gene clusters that they regulate (those for virginiamycin M and virginiamycin S [27]). Similarly, although initially recognized by their role in regulating Act and Red production, the corresponding genes of S. coelicolor, scbA and scbR, are adjacent to, and directly regulate, a ...
... secondary metabolic gene clusters that they regulate (those for virginiamycin M and virginiamycin S [27]). Similarly, although initially recognized by their role in regulating Act and Red production, the corresponding genes of S. coelicolor, scbA and scbR, are adjacent to, and directly regulate, a ...
vysoké učení technické v brně molecular signature as optima of
... the technical literature and other sources of information which are quoted in the project and detailed in the list of literature at the end of the project. As the author of the project I furthermore declare that, as regards the creation of this final project, I have not infringed any copyright. In p ...
... the technical literature and other sources of information which are quoted in the project and detailed in the list of literature at the end of the project. As the author of the project I furthermore declare that, as regards the creation of this final project, I have not infringed any copyright. In p ...
Meiosis
... • Called a reduction division (because # of chromosomes is reduced) • Meiosis is sexual reproduction • Two divisions (meiosis I and meiosis ...
... • Called a reduction division (because # of chromosomes is reduced) • Meiosis is sexual reproduction • Two divisions (meiosis I and meiosis ...
DNA How the Molecule of Heredity Carries, Replicates, and
... DNA stores information in the sequence of its bases. •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. ...
... DNA stores information in the sequence of its bases. •Much of DNA’s sequence-specific information is accessible only when the double helix is unwound. •Proteins read the DNA sequence of nucleotides as the DNA helix unwinds. Proteins can either bind to a DNA sequence, or initiate the copying of it. ...
A rapid and specific PCR–ELISA for detecting Salmonella typhi
... providing highly specific results in a shorter time by using biotin-label primers which improve the specificity of the assay. The advantage of the DIGELISA is the simplicity of the method, together with the solid-phase 96-well (or even 384-well) microplate format, which allows many samples to be ana ...
... providing highly specific results in a shorter time by using biotin-label primers which improve the specificity of the assay. The advantage of the DIGELISA is the simplicity of the method, together with the solid-phase 96-well (or even 384-well) microplate format, which allows many samples to be ana ...
Repair of Site-Specific DNA Double-Strand Breaks in
... Direct ligation of break ends after cleavage by I-SceI would restore the I-SceI recognition site. We detected 33.42% of reads (2563 reads) from GU.US, 17.56% (1672 reads) from DU.GUS, and 24.86% (1783 reads) from IU.GUS that displayed the original I-SceI site (Figure 4B; Supplemental Tables 1 and 2) ...
... Direct ligation of break ends after cleavage by I-SceI would restore the I-SceI recognition site. We detected 33.42% of reads (2563 reads) from GU.US, 17.56% (1672 reads) from DU.GUS, and 24.86% (1783 reads) from IU.GUS that displayed the original I-SceI site (Figure 4B; Supplemental Tables 1 and 2) ...
Functional gene groups are concentrated within chromosomes
... of genes within each chromosome separately. In this way we accounted for clustering effects due to concentration of genes from the same group on few chromosomes. The results show that the average intra-chromosomal distance between genes from the same complex and pathway is significantly smaller than ...
... of genes within each chromosome separately. In this way we accounted for clustering effects due to concentration of genes from the same group on few chromosomes. The results show that the average intra-chromosomal distance between genes from the same complex and pathway is significantly smaller than ...
Gsp1 Triggers the Sexual Developmental Program
... that the increased biparental transmission of cpDNA might be an indirect effect of the reduced amount of mt+ cpDNA (Armbrust et al., 1995; Umen and Goodenough, 2001). In the related species Chlamydomonas monoica, two mutants have been obtained that alter uniparental inheritance. The mtl-1 mutant fai ...
... that the increased biparental transmission of cpDNA might be an indirect effect of the reduced amount of mt+ cpDNA (Armbrust et al., 1995; Umen and Goodenough, 2001). In the related species Chlamydomonas monoica, two mutants have been obtained that alter uniparental inheritance. The mtl-1 mutant fai ...
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics
... either alone or together with exposure to asbestos. ...
... either alone or together with exposure to asbestos. ...
Biology (SPA)
... things, was the first to refer to the cavities he saw in cork as ‘cells’, Latin for chambers. Subsequent scientists developed Hooke’s discovery of the cell into the Cell Theory on which modern Biology is built upon. The Cell Theory states that all organisms are composed of one or more cells, and tha ...
... things, was the first to refer to the cavities he saw in cork as ‘cells’, Latin for chambers. Subsequent scientists developed Hooke’s discovery of the cell into the Cell Theory on which modern Biology is built upon. The Cell Theory states that all organisms are composed of one or more cells, and tha ...
computation for chIP-seq and rNA-seq studies
... on (i) achieving sufficient enrichment of factor-bound chromatin relative to nonspecific chromatin background and (ii) obtaining sufficient enriched chromatin so that each sequence obtained is from a different founder molecule in the ChIP reaction (in other words, that the molecular library has adeq ...
... on (i) achieving sufficient enrichment of factor-bound chromatin relative to nonspecific chromatin background and (ii) obtaining sufficient enriched chromatin so that each sequence obtained is from a different founder molecule in the ChIP reaction (in other words, that the molecular library has adeq ...
splicing
... RNAi that targets the gene’s control region, a promoter-associated transcript) rather than the coding region • Another silencing mechanism targets nuclear RNA as endogenous double-stranded siRNAs that contain a nuclear localization signal can enter the nucleus and cause degradation of nuclear RNAs b ...
... RNAi that targets the gene’s control region, a promoter-associated transcript) rather than the coding region • Another silencing mechanism targets nuclear RNA as endogenous double-stranded siRNAs that contain a nuclear localization signal can enter the nucleus and cause degradation of nuclear RNAs b ...