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g.ML-6 DNA Replication1
g.ML-6 DNA Replication1

... 1. To complete the replication of DNA in the normal S period of the cell cycle requires that multiple sites of DNA replication be initiated. For our average chromosome of 150 million bps, how many polymerases are needed to complete the replication in 8 hours with polymerases that move at 50 bp/s? 2. ...
Chapter 12
Chapter 12

... – Only 1.5% of the DNA codes for proteins, tRNAs, or rRNAs – The remaining 88.5% of the DNA contains – Control regions such as promoters and enhancers – Unique noncoding DNA – Repetitive DNA – Found in centromeres and telomeres – Found dispersed throughout the genome, related to transposable element ...
Biology Second Semester Study Guide Molecular Genetics (Chapter
Biology Second Semester Study Guide Molecular Genetics (Chapter

... investigation into the origin of life. Miller took molecules which were believed to represent the major components of the early Earth's atmosphere (Water, Hydrogen, Ammonia, and Methane (WHAM)) and put them into a closed system. The gases they used were methane (CH4), ammonia (NH3), hydrogen (H2), a ...
Recombinant Biotechnology
Recombinant Biotechnology

... And, Vectors… …contain unique restriction sites to facilitate the creation of recombinant DNA molecules, ... must also possess a distinguishing physical characteristic such as size or shape by which it can be purified away from the host cells genome. ...
lecture notes-molecular biology-central dogma
lecture notes-molecular biology-central dogma

Chapter 13 Genetics and Biotechnology
Chapter 13 Genetics and Biotechnology

... laboratories for biological research. Mice, fruit flies, and the roundworm Caenorhabditis elegans to study diseases and ways to treat them. Transgenic livestock – to improve food supply and human health. Transgenic goats – to secrete a protein called antithrombin III, which is used to prevent human ...
Problem Set 4B
Problem Set 4B

... C. Deletion (4 bases) mutation in the DNA polymerase gene. Shift of the reading frame will cause a non functional protein to be translated. If this is the only DNA polymerase gene, the cell will likely die. D. Loss of function mutation in a Mismatch Repair protein gene. Mismatch repair is disabled b ...
Topic: Genetic Mutations
Topic: Genetic Mutations

... Substitution (point) mutation = when one base is replaced with another Results in transcription and translation of a different amino acid than expected. Sickle Cell Anemia  disease where substitution occurs on one base ...
DNA Technology and Genomes
DNA Technology and Genomes

... impact, unknown effect on other organisms, loss of flora and fauna biodiversity Access and Intellectual Property: domination of world food production by few companies; increased dependence on industrial nations by developing countries; Ethics: violation of natural organisms’ intrinsic values; tamper ...
gene
gene

... usually antibiotic or herbicide resistance, etc. (i.e. only the organisms with the T-DNA live in a selection experiment), ...
DNA: the Genetic Material Chapter 9.1
DNA: the Genetic Material Chapter 9.1

... Chromosome – Structure made of DNA & Protein on which genes are located.  I know that for the most part you’re thinking to yourself, “Uuuhhhh, so what!”  Well almost 100 years ago this was a ginormous issue.  Biologists knew that chromosomes carried genetic material, but there was something that ...
Introduction - Cedar Crest College
Introduction - Cedar Crest College

... Telomeres are moderately repetitive sequences at the end of the chromosomes. They are specialized sequences and are not transcribed into RNA. ...
Transcription
Transcription

... Processing the mRNA Transcript In eukaryotic cells, the newly-formed mRNA transcript (also called heterogenous nuclear RNA or hnRNA) must be further modified before it can be used. A cap is added to the 5’ end and a poly-A tail (150 to 200 Adenines) is added to the 3’end of the molecule. Eukaryotic ...
Genes, Protein Synthesis, and Mutations
Genes, Protein Synthesis, and Mutations

... and connecting them into a stand of mRNA. c. This single strand of properly ordered bases (the mRNA) leaves the nucleus and attaches one end of itself to a ribosome. 1. The code on the mRNA is read by the ribosome 3 bases at a time. a. This 3-base group is called a codon. d. A second type of RNA, ca ...
gelfand-genetic-code
gelfand-genetic-code

Document
Document

Plant transposons
Plant transposons

... TEs can alter gene expression Can this have phenotypic consequences? ...
Chapter Outline
Chapter Outline

... a. Some proteins are not active after synthesis; the polypeptide product has to undergo additional changes before it is biologically functional. b. Bovine proinsulin, for example, is inactive when first produced; a single long polypeptide folds into a three-dimensional structure, a sequence of 30 am ...
RNA - Humble ISD
RNA - Humble ISD

... where a gene starts and stops? Enzyme binds to places with specific DNA PROMOTERS sequences called _______________. RNA POLYMERASE PROMOTERS tell _________________ where to start. Signals at the end of the gene code cause transcription to _____ stop . http://images2.clinicaltools.com/images/gene/dna ...
ALE 10.
ALE 10.

... 37. Which of the following mutations would likely be most dangerous to a cell? a.) Deletion of three nucleotides b.) Substitution of one nucleotide for another c.) Addition of one nucleotide d.) Addition of three nucleotides 38. In the disease of sickle cell anemia (autosomal recessive), a single ba ...
Sex Chromosomes
Sex Chromosomes

... Physical attractiveness of premature infants affects outcome at discharge from the NICU Badr, LK & Abdallah, B (2001) Infant Behavior and Development, vol. 24, p. 129+ ...
One Gene- One Enzyme Theory 2016 EHSS 920KB Feb 17
One Gene- One Enzyme Theory 2016 EHSS 920KB Feb 17

Abstract Dissertation Makhalova
Abstract Dissertation Makhalova

... side effect of chemotherapy with DNA reactive drugs such as cisplatin. The underlying mechanisms, however, are still not clear. Platinum compounds are known to exert their antineoplastic activity by forming distinct Pt-DNA adducts. Both the DNA repair rates and the extent of tolerance to persisting ...
DNA and the Genome - Speyside High School
DNA and the Genome - Speyside High School

... Splice site mutations RNA splicing is important in creating the mature mRNA transcript. Mutations in the area that marks the start or end of an intron, may lead to one or more introns not being removed. This will lead to a creation of a protein that does not function properly. CFE Higher Biology ...
R N A & PROTEIN SYNTHESIS
R N A & PROTEIN SYNTHESIS

... clog tiny blood vessels impeding the flow of blood. Sickle-cell anemia kills about 100,000 people per year in the US ...
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Non-coding DNA

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