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On-line tools for sequence retrieval and
On-line tools for sequence retrieval and

... statistics for sequence analysis, it has to provide access to sequence data banks. For that purpose we have developed WWW-Query, a WWW version of the retrieval system Query (Gouy et al., 1985). As with its standalone predecessor, WWW-Query allows users to make complex queries on various sequence ban ...
Whole Genome Annotations Experimental data involving thousands
Whole Genome Annotations Experimental data involving thousands

A unique pattern of intrastrand anomalies in base
A unique pattern of intrastrand anomalies in base

... two strands in the 26 molecules with unidentified coding functions are similar to the values for the 46 molecules with identified coding functions (Fig. 2c). The data for the two strands of the 26 molecules are combined because the orientation of their ORFs are unknown, and therefore leader and trai ...
Exam 2
Exam 2

... B. mitochondrial DNA has a higher mutation rate in African environments. C. gene flow occurred between Homo sapiens and other Homo species in Africa. D. natural selection does not operate on mitochondrial DNA in African environments. Question 11 In his theory of evolution by natural selection, Darwi ...
RNA Class: The Classification
RNA Class: The Classification

... synthesis. Although we have not found what kind of role rRNA plays in this process, we can not deny the importance of rRNA. Small RNA Small RNA is generally made by two parts: small nuclear RNA(snRNA), which exists in nucleus; small cytoplasmic RNA(scRNA), which exists in cytoplasm. Small nuclear RN ...
Protective action of vitamin C against DNA damage induced by
Protective action of vitamin C against DNA damage induced by

... Genotoxicity of anticancer drugs is of a special interest due to the risk of inducing secondary malignancies. Vitamin C (ascorbic acid) is a recognized antioxidant and, since human diet can be easily supplemented with vitamin C, it seems reasonable to check whether it can protect against DNA-damagin ...
Heredity The passing of traits from parent to offspring
Heredity The passing of traits from parent to offspring

... Caused by the absence of a necessary enzyme that breaks down fatty substances (on chromosome 15) Causes a build up of fatty deposits in the brain and mental disabilities; Causes a dark spot in the back of the eye (how doctors are able to identify the disease) Affects 1 in 2500 people in the US (usua ...
Maxime - Tech Dragon Limited
Maxime - Tech Dragon Limited

Lecture Slides - McMaster University`s Faculty of Health Sciences
Lecture Slides - McMaster University`s Faculty of Health Sciences

... Is there distortion in allele sharing? Model free, less vulnerable to misclassification Major challenge is power; esp when there is genetic (locus) heterogeneity! ...
RNA Tertiary Structure
RNA Tertiary Structure

... the 3' untranslated region of their target mRNAs, preventing functional proteins from being produced during certain stages of larval development. • Additional studies indicate that miRNAs also play significant roles in cancer and other diseases. For example, the species miR-155 is enriched in B cell ...
here. - the DeRisi Lab
here. - the DeRisi Lab

... measurements of gene expression for every gene in a whole genome, which has been used to gain important insights into processes such as development, responses to environmental perturbations, gene mutation, and host response to pathogens, and cancer ...
No Slide Title
No Slide Title

DNA Copy Number Analysis (SGF talk 2007-02-12)
DNA Copy Number Analysis (SGF talk 2007-02-12)

RNA transcription and mRNA processing
RNA transcription and mRNA processing

... of proto-oncogenes leads to overexpression of other genes, because many proto-oncogenes are transcription factors, signal proteins that interact with molecules controlling intracellular growth and growth factors released by cells to stimulate other cells to divide. Overexpression can occur when ther ...
11.7 Repressor binds cooperatively at each operator using a helix
11.7 Repressor binds cooperatively at each operator using a helix

... large number of phage particles, lysis of the cell, and release of the viruses. 2. Lytic infection falls typically into three phases. In the first phase a small number of phage genes are transcribed by the host RNA polymerase. 3. In phage lambda, the genes are organized into groups whose expression ...
Chapter Seventeen: Gene Mutations and DNA Repair
Chapter Seventeen: Gene Mutations and DNA Repair

... other than the gene containing the original mutation. Since many proteins interact with other proteins, the original mutation may have disrupted the protein-protein interaction, while the second mutation restores the interaction. A second type of intergenic suppression occurs when a mutation within ...
Biol207 Final Exam
Biol207 Final Exam

... 15. A Biol207 Professor (not Dr. Locke) was mapping genes in a strain of yeast she uses for making beer. Below is a diagram of a 9 kbp Xba I (X) restriction fragment subcloned from a cosmid clone that she cloned from her Yeast genomic library. The yeast genome is ~13 Mbp. The restriction map for thi ...
The “m”
The “m”

... place within a cell. Must include: Transcription & Translation (what & where and how) ...
AUGUSTUS: a web server for gene prediction in eukaryotes that
AUGUSTUS: a web server for gene prediction in eukaryotes that

... for gene prediction in eukaryotic genomic sequences that is based on a generalized hidden Markov model, a probabilistic model of a sequence and its gene structure. The web server allows the user to impose constraints on the predicted gene structure. A constraint can specify the position of a splice ...
DNA purification and isolation of genomic DNA from bacterial
DNA purification and isolation of genomic DNA from bacterial

... Max Yield System). All of these systems purify genomic DNA that is amenable for use in many downstream applications. Although techniques like Southern blotting, which require microgram amounts of DNA, are still performed in molecular biology laboratories, most assessment of chromosomal DNA is done b ...
Genomic islands of speciation or genomic islands and speciation?
Genomic islands of speciation or genomic islands and speciation?

... In contrast to our still-developing understanding of differences at the phenotype level, much is now known about genetic differentiation between forms. The forms were originally defined based on the lack of heterozygotes at a single biallelic marker on the X chromosome, proximal to the centromere (d ...
Nucleic acid crystallography: current progress
Nucleic acid crystallography: current progress

... (such repetitive regions are encountered throughout the genomes of all vertebrates), whereby two quadruplexes associate into an octaplex under formation of four central G-tetrad layers. An unusual form of self-association is also seen in the structure of d(GCATGCT). Two strands fold into a complemen ...
Compiling DNA strand displacement reactions using a functional
Compiling DNA strand displacement reactions using a functional

... Previous work has shown that synthetic DNA circuits can be used to implement computational systems including digital logic circuits [1], neural networks [2] and gameplaying automata [3]. In this setting, DNA is used both as an information carrier and as an engineering material, simultaneously. Furth ...
Part_of - coccidia.icb.usp.br
Part_of - coccidia.icb.usp.br

... • Gene products: e.g. cytochrome c is not in the ontologies, but attributes of cytochrome c, such as oxidoreductase activity, are. • Processes, functions or components that are unique to mutants or diseases: e.g. oncogenesis is not a valid GO term because causing cancer is not the normal function of ...
Genetics of Quantitative Variation in Human Gene Expression
Genetics of Quantitative Variation in Human Gene Expression

... In this study, we have assessed the extent of natural variation in gene expression in humans. Our results suggest that there is a genetic component to this variation. Next, we will identify the genetic determinants for this variation. Identification and characterization of these determinants, called ...
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Non-coding DNA

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