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paper by Acquisti, Elser and Kumar
paper by Acquisti, Elser and Kumar

... reflects differences in the overall contribution of RNA and DNA to cellular biomass: DNA generally contributes less than 2% to overall organismal biomass, whereas RNA can constitute up to 15% of the biomass in multicellular eukaryotes (Sterner & Elser 2002; Elser et al. 2003). These results are also ...
DNA Molecular Structure
DNA Molecular Structure

... for one amino acid – codon - the 3 base sequence in mRNA – 64 possible codons available to represent the 20 amino acids • 61 code for amino acids • Stop Codons – UAG, UGA, and UAA – signal the ‘end of the message’, like a period at the end of a sentence • Start Codon – AUG codes for methionine , and ...
Gene Regulation III Reminder
Gene Regulation III Reminder

... molecules to regulate gene expression • 2 sources of RNA ‣ cell’s own genes - MicroRNA (miRNA) ‣ viruses and transposons - Small Interfering RNA (siRNA) • Process likely evolved to inactivate viral genes and transposons ...
modification of gene expression
modification of gene expression

... Common minor changes in an Changes in an organism organism caused by caused by modification of modification of the gene gene expression For example, single nucleotide polymorphisms Change in protein structure Change in production of and function protein ...
Lecture_note_463BI
Lecture_note_463BI

... isoacceptor produced by multiple copies of the normal tRNA gene still present in the genome. Dispersion of multiple copies of each tRNA gene could provide diversity of 5-prime-flanking sequences, which are known to modulate the expression of some human tRNA genes. Tissue-specific or differentiation- ...
Genetica per Scienze Naturali aa 05
Genetica per Scienze Naturali aa 05

... (A) Nonhomologous end-joining alters the original DNA sequence when repairing broken chromosomes. These alterations can be either deletions (as shown) or short insertions. (B) Homologous end-joining is more difficult to accomplish, but is much more precise. ...
PHYOGENY & THE Tree of life
PHYOGENY & THE Tree of life

... Many scientists remain skeptical about: the “Neutral Theory”, about using the molecular clock beyond time span documented by fossil record (about 550 million years) ...
Gene Section BCL7B (B-cell CLL/lymphoma 7B) Atlas of Genetics and Cytogenetics
Gene Section BCL7B (B-cell CLL/lymphoma 7B) Atlas of Genetics and Cytogenetics

... gene in human tissues. However, serial analysis of gene expression (SAGE) data suggests that gene transcripts are present at low levels in the brain and a variety of breast cells. Data is not available for other tissues. BCL7B has also been shown to be under-expressed in paediatric pilocytic astocyt ...
Simulating Protein Synthesis to create a CHNOPS! Read the
Simulating Protein Synthesis to create a CHNOPS! Read the

... During transcription, which takes place in the nucleus of the cell, messenger RNA (mRNA) nucleotides read and copy the DNA sequence into a single RNA strand. mRNA can leave the nucleus because it is single stranded. mRNA travels to the ribosome where proteins are made. The codons in the mRNA strand ...
Mutations Worksheet
Mutations Worksheet

... There are several types of genetic point mutations (a change in only one letter of the genetic code): FRAMESHIFT, meaning the reading “frame” changes, changing the amino acid sequence. DELETION (a base is lost) INSERTION (an extra base is inserted) SUBSTITUTION (one base is substituted for another) ...
pptx format
pptx format

... Different organisms diverse from each other by the sequence of the basic breaks and their number. ...
Hands On - Gene Prediction in Prokaryotes file
Hands On - Gene Prediction in Prokaryotes file

... This step follows after the genome of a species has been sequenced. In general, the process includes identifying protein-coding regions, RNA genes, and regulatory regions. The three major categories of gene prediction algorithms are alignment-based, sequence-based, and content-based. Some algorithms ...
DNA: THE CODE OF LIFE
DNA: THE CODE OF LIFE

... • A group of 3 nitrogen bases codes for one specific amino acid. This is known as a CODON. (a sequence of three nucleotides that together form a unit of genetic code in a DNA or RNA molecule.) ...
Gramene: A Resource for Comparative Grass Genomics
Gramene: A Resource for Comparative Grass Genomics

... Tendency for Organization and Growth This common vocabulary is arranged in a structured order or network based on their relationships to each other. Kingdom: Animalia Phylum: Chordata Subphylum: Vertebrata Class: Mammalia Subclass: Theria Infraclass: Eutheria Order: Primates Suborder: Anthropoidea S ...
Class - Educast
Class - Educast

... Uses of Transgenic plants: In order to improve the quality and quantity of plants, traditional method of plant breeding is replaced by the creation of transgenic plants. The transgenic plants are plants carrying foreign genes introduced deliberately into them to develop a new character useful for th ...
Lab 4 Restriction Analysis
Lab 4 Restriction Analysis

... RE's first made it possible to work with small, defined pieces of DNA. Before RE's were discovered, a scientist might be able to tell that a chromosome contained a gene of interest to him. He might be able to purify the protein or use genetic analysis to tell what other genes were close to "his" gen ...
Molecular Genetics
Molecular Genetics

... • 1. Initiation = small ribosomal subunit attaches to a special region near the 5’ end of the mRNA • 2. A tRNA with the anticodon UAC attaches to the mRNA start codon AUG • 3. Large ribosomal subunit now attaches to the mRNA ...
File
File

... • RNA is made by copying part of a nucleotide sequence of DNA • RNA polymerase binds to DNA and separates the strands and uses one strand to make a new strand of RNA • Promoters: RNA polymerase will only bind to the regions of the DNA strand known as promoters ...
The Chemistry of Inheritance
The Chemistry of Inheritance

... This is usually accomplished by the action of another enzyme, helicase. Once the helix is unwound it must be “stabilized” in this open state. This is accomplished by single-stranded binding protein. Before DNA polymerase can extend a strand, it must have a short primer. The primer is synthesized by ...
introduction - Genomics
introduction - Genomics

... singletons). We further describe computational methods to isolate from this set those sequences which are likely to contain a start of translation, and identify the corresponding clones most likely to contain the full coding sequence of the gene concerned. In this manner we have identified approxima ...
Evolving Molecular Methods for Detection of Mutations
Evolving Molecular Methods for Detection of Mutations

... by a DNA ligase. Oligonucleotides complementary to the normal and mutant sequences are differentially labeled and the products are identified by a computer software. Quantitative PCR using Real-time has many applications in biotechnology, there are multiple hardware platforms for real-time PCR, and ...
RNA and Protein Synthesis
RNA and Protein Synthesis

... Congratulations! You have just transcribed and translated DNA into a protein! ...
e1. protein synthesis - Eric Hamber Secondary
e1. protein synthesis - Eric Hamber Secondary

... - Ribosomes move along messenger RNA reading codons and binding amino acids that are in the right place due to the transfer RNA (tRNA). - enzyme on ribosome catalyses the peptide bond - chain grows one amino acid at a time TERMINATION: - Ribosome reads “terminate” codon (UAG) and stops - releases pr ...
Matlab_Bioinformatics_Toolbox
Matlab_Bioinformatics_Toolbox

The nitrogen base that RNA has but DNA does not What is uracil?
The nitrogen base that RNA has but DNA does not What is uracil?

... What are the three components of the DNA molecule? ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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