Archives of Microbiology 167:
... luxAB side of the transposon. Based on BLAST analysis, the amino acid sequence derived from double-stranded nucleotide sequence of a 3,159-bp ORF within this region and from the two HindIII subclones of cosmid clone pSCR213 yields a large, 1,053-amino-acid protein containing two active sites (Fig. 2 ...
... luxAB side of the transposon. Based on BLAST analysis, the amino acid sequence derived from double-stranded nucleotide sequence of a 3,159-bp ORF within this region and from the two HindIII subclones of cosmid clone pSCR213 yields a large, 1,053-amino-acid protein containing two active sites (Fig. 2 ...
Mycobacterium tuberculosis: Potassium uptake systems of
... include the identification of novel and selective targets on/in MTB which are amenable to pharmacological or immune-mediated control. Because they are structurally different from their counterparts in eukaryotic cells and are likely to be essential for survival and growth, the major K+ transporters ...
... include the identification of novel and selective targets on/in MTB which are amenable to pharmacological or immune-mediated control. Because they are structurally different from their counterparts in eukaryotic cells and are likely to be essential for survival and growth, the major K+ transporters ...
Effects of cis and trans Genetic Ancestry on Gene Expression in
... We investigated the effects of cis ancestry and trans ancestry on gene expression in AA. Roughly, we define cis ancestry as the local ancestry at the gene whose expression is being analyzed, and trans ancestry as the average ancestry at non-cis regions. We extended our above model by letting egs = c ...
... We investigated the effects of cis ancestry and trans ancestry on gene expression in AA. Roughly, we define cis ancestry as the local ancestry at the gene whose expression is being analyzed, and trans ancestry as the average ancestry at non-cis regions. We extended our above model by letting egs = c ...
LEADING ARTICLE Concurrent disruption of p16INK4a and
... genes have been demonstrated in NHL.3 As in many other types of cancer, the most commonly altered targets reported in NHL are the genes encoding the tumor suppressors p16INK4a and p53.4–22 These proteins are key components of the machinery that controls cell cycle progression.23,24 p16INK4a exerts a ...
... genes have been demonstrated in NHL.3 As in many other types of cancer, the most commonly altered targets reported in NHL are the genes encoding the tumor suppressors p16INK4a and p53.4–22 These proteins are key components of the machinery that controls cell cycle progression.23,24 p16INK4a exerts a ...
Title: Genes in the Postgenomic Era Authors: Paul E. Griffiths and
... which natural selection can act. Investigations of the physical reality of the gene – beginning with Muller and others' use of X-ray mutagenesis to estimate the size of the genetic target – mark a significant epistemological development in genetics. Because the aim of genetic analysis was to analyze ...
... which natural selection can act. Investigations of the physical reality of the gene – beginning with Muller and others' use of X-ray mutagenesis to estimate the size of the genetic target – mark a significant epistemological development in genetics. Because the aim of genetic analysis was to analyze ...
The dual nature of homologous recombination in plants
... metabolic activities. Numbers are not available for plants, but it has been estimated that 5–10% of first passage primary fibroblasts from mice or humans have a chromosome break (discussed in Ref. [33]). In plants and vertebrates most of these breaks are repaired by nonhomologous-end joining (NHEJ), ...
... metabolic activities. Numbers are not available for plants, but it has been estimated that 5–10% of first passage primary fibroblasts from mice or humans have a chromosome break (discussed in Ref. [33]). In plants and vertebrates most of these breaks are repaired by nonhomologous-end joining (NHEJ), ...
light control of seedling development
... seed, promoting germination particularly under continuous far-red light. Under far-red light, phyB mutant seeds germinate more efficiently than wild type. Thus, the wild-type PHYB allele appears to negate the action of phyA, which provides an example for antagonistic control of the same response by ...
... seed, promoting germination particularly under continuous far-red light. Under far-red light, phyB mutant seeds germinate more efficiently than wild type. Thus, the wild-type PHYB allele appears to negate the action of phyA, which provides an example for antagonistic control of the same response by ...
Polymorphism of the CTNNB1 and FOXL2 Genes is not
... 2002) and roe deer (PAJARES et al. 2009). In two animal species the causative mutations were identified. A deletion of 11.7 kb in the regulatory region localized ~300 kp upstream from FOXL2 is responsible for this disorder in goats (PAILHOUX et al. 2001; BOULANGER et al. 2014). In DSD roe deer, anal ...
... 2002) and roe deer (PAJARES et al. 2009). In two animal species the causative mutations were identified. A deletion of 11.7 kb in the regulatory region localized ~300 kp upstream from FOXL2 is responsible for this disorder in goats (PAILHOUX et al. 2001; BOULANGER et al. 2014). In DSD roe deer, anal ...
Supplementary Notes for the work: "Evolutionary Rate and Gene
... Supplementary Notes for the work: "Evolutionary Rate and Gene Expression Across Different Brain Regions" ...
... Supplementary Notes for the work: "Evolutionary Rate and Gene Expression Across Different Brain Regions" ...
巴西橡胶Pto类抗病同源序列的克隆与系统发育重建
... characterization has provided valuable insights into the disease resistance mechanism of tomato and it is considered as a promising candidate for engineering broad-spectrum pathogen resistance in this crop. In this study, a pair of degenerate primers based on conserved subdomains of plant STKs simil ...
... characterization has provided valuable insights into the disease resistance mechanism of tomato and it is considered as a promising candidate for engineering broad-spectrum pathogen resistance in this crop. In this study, a pair of degenerate primers based on conserved subdomains of plant STKs simil ...
Simulating evolution by gene duplication of protein features that
... our computer model by the constant , which is the ratio of the number of mutations of the original duplicated gene that would produce a null allele to the number of mutations of the original duplicated gene that would yield a compatible residue. (Definitions of terms are given in Table 1.) As an ex ...
... our computer model by the constant , which is the ratio of the number of mutations of the original duplicated gene that would produce a null allele to the number of mutations of the original duplicated gene that would yield a compatible residue. (Definitions of terms are given in Table 1.) As an ex ...
Eds., N. Hamamura, S. Suzuki, S. Mendo, C. M. Barroso,... © by TERRAPUB, 2010.
... As a response to toxic mercury compounds globally distributed by geological activities from the ancient, microbes have developed some astonishing arrays of dedicated resistance systems to overcome the poisonous environment (Barkay et al., 2003). Among those resistance systems, one based on clustered ...
... As a response to toxic mercury compounds globally distributed by geological activities from the ancient, microbes have developed some astonishing arrays of dedicated resistance systems to overcome the poisonous environment (Barkay et al., 2003). Among those resistance systems, one based on clustered ...
The Mammalian Mismatch Repair Pathway Removes DNA 8
... MEF extracts (Figure 3B). There were no detectable differences among the Msh2-proficient and -defective variants of Colo26 in this regard. It is unclear why elevated levels of DNA 8-oxoG coexist with a high Ogg-1 activity in these mouse tumor cells. It may reflect unusual kinetics of the Ogg-1-media ...
... MEF extracts (Figure 3B). There were no detectable differences among the Msh2-proficient and -defective variants of Colo26 in this regard. It is unclear why elevated levels of DNA 8-oxoG coexist with a high Ogg-1 activity in these mouse tumor cells. It may reflect unusual kinetics of the Ogg-1-media ...
A Noise Trimming and Positional Significance of
... where f ( X ) is a mapping function and means "maps to". For an individual gene, we have f ( xi ) ti , where xi is the mutation feature value of the ith gene and ti is the mutation status value of the ith gene. In addition to estimating such a mapping function, the challenge is the data complexi ...
... where f ( X ) is a mapping function and means "maps to". For an individual gene, we have f ( xi ) ti , where xi is the mutation feature value of the ith gene and ti is the mutation status value of the ith gene. In addition to estimating such a mapping function, the challenge is the data complexi ...
Production of Recombinant Molecules
... pieces of tissues or cells and known amount of exogenous DNA are taken in a vial, containing appropriate medium. The micro tip of sonicator is immersed in the suspension and pulses of ultrasound is delivered by sonicator.The vigorous vibration in the medium and violent collapse of bubbles generate h ...
... pieces of tissues or cells and known amount of exogenous DNA are taken in a vial, containing appropriate medium. The micro tip of sonicator is immersed in the suspension and pulses of ultrasound is delivered by sonicator.The vigorous vibration in the medium and violent collapse of bubbles generate h ...
Modeling Fragile X Syndrome Using Human Pluripotent Stem Cells
... the loss-of-function of FMRP leads to neural deficits in FXS fetuses. In addition, the underlying mechanisms for germ line and somatic CGG instabilities in FXS are unknown. In terms of treatment, it would be enormously beneficial to find how/whether FMR1 gene inactivation can be reversed in patients ...
... the loss-of-function of FMRP leads to neural deficits in FXS fetuses. In addition, the underlying mechanisms for germ line and somatic CGG instabilities in FXS are unknown. In terms of treatment, it would be enormously beneficial to find how/whether FMR1 gene inactivation can be reversed in patients ...
Comparative Genomic Hybridization in Chronic B
... been identified in multivariate analyses is a complex karyotype associatedwith an inferior outcome.‘ In contrast, in acute leukemias a number of specific chromosomal changes with high prognostic impact have been The difference between these two groups of leukemias may be due to difficulties inidenti ...
... been identified in multivariate analyses is a complex karyotype associatedwith an inferior outcome.‘ In contrast, in acute leukemias a number of specific chromosomal changes with high prognostic impact have been The difference between these two groups of leukemias may be due to difficulties inidenti ...
Genetics
... Genetics is the study of heredity. Heredity is how traits are passes down from generation to generation. “Father of Genetics”. He studied the way characteristics are passed on in pea plants in the 1800’s. Gregor Mendel ...
... Genetics is the study of heredity. Heredity is how traits are passes down from generation to generation. “Father of Genetics”. He studied the way characteristics are passed on in pea plants in the 1800’s. Gregor Mendel ...
Updated map of duplicated regions in the yeast genome
... regions for which the evidence is weaker. The map was constructed by first identifying the ‘probable’ regions using stringent criteria, and then relaxing the criteria both to add extra ‘possible’ genes to the blocks already identified, and to find additional ‘possible’ blocks. These ‘possible’ genes ...
... regions for which the evidence is weaker. The map was constructed by first identifying the ‘probable’ regions using stringent criteria, and then relaxing the criteria both to add extra ‘possible’ genes to the blocks already identified, and to find additional ‘possible’ blocks. These ‘possible’ genes ...
Figure S1. Interactions between AS1 and CO proteins that contains
... (a) SUC2:AS1-HA and 35S:AS1-HA plants were grown under indicated conditions and flowered slightly earlier than the wild-type plants under 12L/12D and 10L/14D conditions. The levels of AtGA20ox1 transcripts were increased in the transgenic plants (Fig. S4) but FT transcripts were not changed, indicat ...
... (a) SUC2:AS1-HA and 35S:AS1-HA plants were grown under indicated conditions and flowered slightly earlier than the wild-type plants under 12L/12D and 10L/14D conditions. The levels of AtGA20ox1 transcripts were increased in the transgenic plants (Fig. S4) but FT transcripts were not changed, indicat ...
Gene expression patterns in human placenta
... trophoblasts, interposed fibrinoid, and the endometrial components (stromal and fibroblast-like cells, as well as some macrophages, veins, and arteries). Genome-scale transcriptional profiling has been used to study many human diseases and physiological processes, as well as to characterize gene-exp ...
... trophoblasts, interposed fibrinoid, and the endometrial components (stromal and fibroblast-like cells, as well as some macrophages, veins, and arteries). Genome-scale transcriptional profiling has been used to study many human diseases and physiological processes, as well as to characterize gene-exp ...
METHODS FOR FEMALE MAMMALIAN SPERMATOGENESIS AND
... the gonad in which it finds itself”. Indeed, in the 1980s, it was observed that male mice could have developed their own eggs by colonizing their developing adrenal glands with primordial germ cells. The resulting male eggs, except for their localization and for being surrounded by adrenal cells, we ...
... the gonad in which it finds itself”. Indeed, in the 1980s, it was observed that male mice could have developed their own eggs by colonizing their developing adrenal glands with primordial germ cells. The resulting male eggs, except for their localization and for being surrounded by adrenal cells, we ...
Sleeping Beauty - Weber State University
... The first step of reactivating the transposase gene was to restore an open reading frame (SB1 through SB3 in Figure 1B) from bits and pieces of two inactive TcEs from Atlantic salmon (Salmo salar) and a single element from rainbow trout (Oncorhynchus mykiss) (Radice et al., 1994), by removing the pr ...
... The first step of reactivating the transposase gene was to restore an open reading frame (SB1 through SB3 in Figure 1B) from bits and pieces of two inactive TcEs from Atlantic salmon (Salmo salar) and a single element from rainbow trout (Oncorhynchus mykiss) (Radice et al., 1994), by removing the pr ...