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No Slide Title
No Slide Title

... sequence that consists of a variable number of repeats of the trinucleotide CGG. This sequence occurs in a part of the gene that is transcribed but is not translated into protein. The normal number of CGG repeats varies between 5 and about 50 (average around 30). Individuals with fragile X syndrome ...
MICR 130 Chapter 8
MICR 130 Chapter 8

... §  In eukaryotes, genetic recombination happens regularly as part of sexual cycle §  Chromosomes are close together in nucleus §  Recombination within one organism §  In prokaryotes, transfer of genes happens by: ...
Recombinant DNA
Recombinant DNA

... into human cells for the treatment of genetic disorders, cardiovascular disease and cancer. • Various methods of gene transfer have been used. – Viruses, genetically modified to be safe, can be used to introduce a normal gene into the body. – Liposomes, microscopic globules of lipids, can also be us ...
SCIENTIFIC BACKGROUND OF GENETICS A
SCIENTIFIC BACKGROUND OF GENETICS A

... greater than 3 billion base pairs--an enormous amount by any measure. All of this information must be organized in such a manner that it can be packaged inside the nucleus of the cell. To accomplish this, DNA is complexed with histones to form chromatin. Histones are special proteins that the DNA mo ...
B - Computational Systems Biology Group
B - Computational Systems Biology Group

... The threshold is based on levels (e.g., Type I error rate of 0.05) of distribution of GO terms The rationale: genes are ...
Procaryotic Cell Structure, cont.
Procaryotic Cell Structure, cont.

... Genes are located along chromosomes. An organism's complete collection of genes is referred to as its genotype or genome. ...
www.bio-complexity.com
www.bio-complexity.com

...  Important to be aware of the phenotypic heterogeneity – link between clinicians and genomics experts  Although overall burden of ADRs is high, the incidence of individual ADRs may be low or rare in many instances – so patient identification can be difficult (cf. Type 2 Diabetes) ...
Solid Tumour Section Bone: t(9;17)(q22;p13) in aneurysmal bone cyst
Solid Tumour Section Bone: t(9;17)(q22;p13) in aneurysmal bone cyst

... OSAD (osteoadherin), is a member of the small leucine richrepeat proteoglycan (SLRP) family. It is an extracellular matrix keratan sulfate proteoglycan restricted to mineralized tissues. OMD is a marker for terminally differentiated matrix producing osteoblasts. OMD expression enhances the different ...
Solid Tumour Section Soft tissue tumors: Alveolar rhabdomyosarcoma in Oncology and Haematology
Solid Tumour Section Soft tissue tumors: Alveolar rhabdomyosarcoma in Oncology and Haematology

... Most ARMS cases contain one of two recurrent chromosomal translocations: t(2;13)(q35;q14) or t(1;13)(p36;q14). Reciprocal balanced translocations are often present for the 2;13 translocation. The 1;13 is sometimes visible as a balanced translocation, and other times is associated with a subsequent a ...
A Novel H-NS-like Protein from an Antarctic Psychrophilic Bacterium
A Novel H-NS-like Protein from an Antarctic Psychrophilic Bacterium

... reduced thermal energy, enzymatic proteins with a high specific activity are produced (4). At the molecular level, all proteins from psychrotrophic organisms studied so far have shown a decrease in their intramolecular interactions, usually associated with both higher flexibility and lower thermal s ...
If there is time OR when we get to Cell Unit…
If there is time OR when we get to Cell Unit…

... It is possible to copy more than one recipe -- for example, for a vegetable side dish & dessert, as well as the main dish -- in preparing a meal. ...
Chpt15_PosNegCntrl.doc
Chpt15_PosNegCntrl.doc

... Isolation and purification of the protein was greatly aided by use of mutant strain with up-promoter mutations for lacI, so that many more copies of the protein were present in each cell. This general strategy of over-producing the protein is widely used in purification schemes. Now the gene for the ...
Genes and Chromosomes ppt
Genes and Chromosomes ppt

... HERE’S AN EXAMPLE: Genes associated with vision in humans are located on the X chromosome. – Males only have ONE X chromosome!!!! This can be a problem if the X chromosome given to him by Mom has a ...
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,

... gene therefore fuses with the second exon of BCL6, resulting in a 5' partner - 3' BCL6 fusion transcript; it is supposed that substitution of the promoter of BCL6 may be responsible for BCL6 regulation, or that a break in the breakpoint cluster region of BCL6 may inhibit a sequence involved in BCL6 ...
Glossary Excerpted with modification from the Glossary in Genes V
Glossary Excerpted with modification from the Glossary in Genes V

... Promoter is a region of DNA involved in binding of RNA polymerase to initiate transcription. -10 sequence is the consensus sequence TATAATG centered about 10 bp before the startpoint of a bacterial gene. It is involved in the initial melting of DNA by RNA polymerase. -35 sequence is the consensus s ...
Dominant Gene
Dominant Gene

... - means of tracing sex-linked traits in family trees through a pictorial representation - females are represented by circles, males are represented as squares. - matings are shown by horizontal lines connecting two individuals - offsprings are connected by vertical lines to the mating line - differe ...
Figure 1 - York College of Pennsylvania
Figure 1 - York College of Pennsylvania

... • Using bioinformatics, sorl1 was located on chromosome 15 of zebrafish and 11 in humans. These two chromosomes share many similar genes demonstrating synteny. • In situ shows where sorl1 is being expressed spatially and temporally in development. ...
Gene Expression Profiles and Microarray Data Analysis - BIDD
Gene Expression Profiles and Microarray Data Analysis - BIDD

... are expressed and responsible for a functionality • Compare samples from healthy and sick host to find gene-disease connection • Analyze samples to differentiate sick and healthy, ...
Meiosis ppt
Meiosis ppt

... most of their cytoplasm, remodel their cell shape, and grow a long flagellum (tail). ...
PDF
PDF

... Mouse Zfy1 and Zfy2 encode zinc finger transcription factors that map to the short arm of the Y chromosome (Yp). They have previously been shown to promote meiotic quality control during pachytene (Zfy1 and Zfy2) and at the first meiotic metaphase (Zfy2). However, from these previous studies additio ...
Supporting Information Legends
Supporting Information Legends

Chavis Biology
Chavis Biology

... chain which, in turn, distinguishes one protein from another in structure and function. Another type of RNA, transfer RNA (tRNA), is vital in assembling amino acids into the correct sequence for the required protein by transferring amino acids to the ribosomes when needed. There are twenty different ...
Standard B-4: The student will demonstrate an understanding of the
Standard B-4: The student will demonstrate an understanding of the

... chain which, in turn, distinguishes one protein from another in structure and function. Another type of RNA, transfer RNA (tRNA), is vital in assembling amino acids into the correct sequence for the required protein by transferring amino acids to the ribosomes when needed. There are twenty different ...
Standard B-4: The student will demonstrate an
Standard B-4: The student will demonstrate an

... chain which, in turn, distinguishes one protein from another in structure and function. Another type of RNA, transfer RNA (tRNA), is vital in assembling amino acids into the correct sequence for the required protein by transferring amino acids to the ribosomes when needed. There are twenty different ...
Ch 7- The Cellular Basis of Inheritance
Ch 7- The Cellular Basis of Inheritance

... – 2 identical diploid daughter cells for development, growth and repair (in multicellular organisms such as animals) ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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