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WOX4 - Durham Research Online
WOX4 - Durham Research Online

... promoters results in both increased vascular cell division, and organisational defects in the vascular tissue. This is consistent with a role for localised CLE41 expression providing a positional signal to PXY that is required for correct orientation of the division plane in vascular stem cells (sup ...
Targeting construct, targeting, and generation of Gclc floxed
Targeting construct, targeting, and generation of Gclc floxed

... neomycin resistance gene (neoR) flanked by loxP sites was cloned into the Sac I site in intron 3 of the Gclc gene, and an additional loxP site was cloned into the Bgl II site in intron 6, which is proximal to the exon 6 splice-donor site. The construct also contained the herpes simplex virus thymidi ...
G 1 - University of Queensland
G 1 - University of Queensland

... be lost by collapsing to the first principal component. The principal ellipses of the two groups are shown as solid curves. ...
Clinical Cancer Genetics - Scioto County Medical Society
Clinical Cancer Genetics - Scioto County Medical Society

... You ask her about her family history: – Mother with breast cancer - age 58 – Maternal aunt with breast cancer – age 65 – Paternal grandmother with breast cancer – age 79 She feels that with her family history, breast cancer is ...
Natural products and orphan megasynthases
Natural products and orphan megasynthases

... the forces involved in the interactions between the atoms of the binding domain, the potential building block molecules and surrounding water molecules using the Amber molecular dynamics package on the Pan cluster. The system simulated can include over 50,000 atoms that are in constant motion (Figur ...
The regulation of expression of the porin gene ompC
The regulation of expression of the porin gene ompC

... of the growth medium. In order to control for this variable, we varied the carbon source to slow the growth rate of strains MH513 and MH225 and monitored the effect on P-galactosidase at pH 6. Growth of cells of strain MH225 (ompC-lacZ) at pH 6 with either glycerol or succinate as sole carbon source ...
Somatic Mutations in HLA Genes - ASHI-U
Somatic Mutations in HLA Genes - ASHI-U

... CN: Copy Number change is the result of a deletion or amplification (such as a duplication) of a genetic locus. UPD: UniParental Disomy is the result of duplication of one parental chromosome during mitosis and loss of the other parental chromosome, resulting in homozygosity without CN change. LOH: ...
Supplementary Text Comparisons of X and autosomal expression
Supplementary Text Comparisons of X and autosomal expression

lecture_10(LP)
lecture_10(LP)

... This repair system also corrects alkylation damage induced by chemical mutagens (e.g. EMS, MMS, etc.) ...
Study Guide - Mrs. Averett`s Classroom
Study Guide - Mrs. Averett`s Classroom

... focus on a single gene or set of genes. Genotype typically refers to the genetic makeup of a particular set of genes. Phenotype refers to the physical characteristics resulting from those genes. An alternative form of a gene is an allele. The pea plants that Mendel worked with had two alleles for ea ...
A framework for describing genetic diseases
A framework for describing genetic diseases

... showing the affected and unaffected people within a family; these pedigrees also provide some clues as to which genes and chromosomes may be involved and the strength of the mutation’s effect (penetrance). In order to be inherited, a genetic mutation must not destroy a person’s ability to reproduce. ...
Evidence for Compensatory Evolution of Ribosomal Proteins in
Evidence for Compensatory Evolution of Ribosomal Proteins in

... the mitochondria (mRPs) than for RPs acting in the cytoplasm (cRPs). We took advantage of recently sequenced transcriptomes from two populations of T. californicus (Barreto et al. 2011) to test whether mRPs show higher rates of functional evolution than cRPs, as predicted by the mitonuclear coadapta ...
1 - life.illinois.edu
1 - life.illinois.edu

The Science of Healthy Ageing, Professor Dame Linda Partridge
The Science of Healthy Ageing, Professor Dame Linda Partridge

... a mutation in the gene called Checo which encodes a protein which just sits just inside the receptor in the cell. You can see the nice extension of life span in the flies that have one either one carpean or injured both copies of the checo gene in red, quite a big extension of life span. On the rig ...
BMC Research Notes - FABI
BMC Research Notes - FABI

... tRNA-meth on the opposite strand, while other bacteria (B. quintana, B. melitensis, R. palustris, M. loti, S. meliloti) encode the tRNA/rRNA methyltransferase protein. This gene, however, was different from the cloned tRNA-meth (trmU) Las gene. On the other hand, there is a membrane protein coding g ...
RF cloning: A restriction-free method for inserting target genes into
RF cloning: A restriction-free method for inserting target genes into

... positive clones is directly correlated to the effectiveness of the restriction digests. To circumvent these limitations, different approaches have been taken to enhance cloning efficiency, such as positive selection, in which only colonies containing plasmids with inserts survive or discrimination o ...
NAME _________________ 2009 AP BIOLOGY GENETICS TEST If
NAME _________________ 2009 AP BIOLOGY GENETICS TEST If

... (A) an autosomal chromosome of each parent (B) the Y chromosome contributed by the father (C) the X chromosome contributed by the mother (D) the X chromosome contributed by the father (E) the Y chromosome contributed by the mother 37. What is the probability that the next child of parents A and B wo ...
Axial homeosis and appendicular skeleton defects in mice with a
Axial homeosis and appendicular skeleton defects in mice with a

... the anteroposterior (A-P) axis. The 3′ genes extend more anteriorly while those on the 5′ end of the complex are limited to more posterior regions (Duboule and Dollé, 1989; Graham et al., 1989). This latter property has been termed structural colinearity. Metamere formation along the primary axis of ...
Transcriptional Regulation by FOXP1, FOXP2, and
Transcriptional Regulation by FOXP1, FOXP2, and

... Molecular Cloning of Homo sapiens FOXP1, FOXP2, and FOXP4 cDNA The FOXP1 (GenBank: BC152752; encodes 677 amino acids), FOXP2 (GenBank: BC143867, encodes 714 amino acids), and FOXP4 (GenBank: BC052803, encodes 678 amino acids) cDNA were obtained from the DNASU Plasmid Repository or the Mammalian Gene ...
Know the Facts: Ovarian Cancer
Know the Facts: Ovarian Cancer

... women will die of ovarian cancer in the United States. Mortality rates for ovarian cancer have declined only slightly in the forty years since the “War on Cancer” was declared. However, other cancers have shown a much greater reduction in mortality, due to the availability of early detection tests a ...
Two-Component System of Mycobacterium Tuberculosis
Two-Component System of Mycobacterium Tuberculosis

... the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein belongs to OmpR/PhoB subfamily, which is considered as the largest of the response regu ...
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences

... to micromolar concentrations. These results suggest that free intracellular zinc may be in the range of 1025 M. Zinc transport was induced by growth in zinc. The cadA gene is regulated by the CadC repressor (32), a member of the ArsR family of metalloregulatory proteins (33). However, no genes for h ...
Peromyscus polionotus (the monogamous mouse)
Peromyscus polionotus (the monogamous mouse)

Structural Location of Disease-associated Single
Structural Location of Disease-associated Single

... to 129 PDB structures For dbSNP – 558 variants in 339 alleles mapped to 263 PDB structures ...
Chromatin Structure 1
Chromatin Structure 1

... genes that are normally active are transposed into a position adjacent to heterochromatin, they tend to become inactivated. •Facultative heterochromatin is chromatin that has been specifically inactivated during certain phases of an organism’s life. Although cells of females contain two X chromosome ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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