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Protein domains as units of genetic transfer
Protein domains as units of genetic transfer

... Genomes evolve as modules. In prokaryotes (and some eukaryotes), genetic material can be transferred between species and integrated into the genome via homologous or illegitimate recombination. There is little reason to imagine that the units of transfer correspond to entire genes; however, such uni ...
Virus-mediated reprogramming of gene expression in plants John A
Virus-mediated reprogramming of gene expression in plants John A

... Viral vector transfection systems enable the overproduction of proteins and metabolites in amounts that could be lethal or deleterious to the regenerating plant if introduced by traditional plant transformation methods. Plant viruses can thus be used for complex metabolic pathway engineering involvi ...
DNA research
DNA research

... Results of homology searches for deduced products of ORFs are summarized in Table 1. Among 12 ORFs, sspC was the only known B. subtilis gene mapped and characterized in this region.7 The putative products of yojV, yojW, yojX, yojYand yojZshowed no significant homology to any known proteins in the da ...
Microbial diversity and virulence probing of five different body sites
Microbial diversity and virulence probing of five different body sites

... clustering of COGs across metagenomes •Can also show Hierarchical clustering by Function (COG, Pfam etc) or ...
synthesis Gene Cluster of Streptomyces clavuligerus
synthesis Gene Cluster of Streptomyces clavuligerus

... et al., 1991). Analysis of the nucleotide sequence of the entire fragment using the Geneplot Program of DNAstar revealed the presence of eight ORFs, oriented in the same direction. Comparison of the amino acid sequences deduced from the ORFs with the sequences of arginine metabolic enzymes shows tha ...
Linkage Analysis and Mapping
Linkage Analysis and Mapping

... • Recombination is caused by formation of chiasmata along the chromosome at multiple points. • If the distance between two genes is large enough, there can potentially be multiple chiasmata formation between them; – so there could be multiple crossovers. • What would happen if there were two crossov ...
The genomic substrate for adaptive radiation in African cichlid fish
The genomic substrate for adaptive radiation in African cichlid fish

... A. burtoni: 11 tissues (blood, brain, eye, embryo, heart, kidney, liver, muscle, ovary, skin and testis) were isolated from several individuals inbred for ∼ 60 generations in the laboratory of Dr. Hans Hoffman (University of Texas at Austin, Austin, TX, USA). Tissues for RNA were collected and place ...
Expression of E. coli Phosphofructokinase Gene in an Autotrophic
Expression of E. coli Phosphofructokinase Gene in an Autotrophic

... was stimulated by the consumption of glucose but its ability to consume the glucose was limited. The expression of the pfkA gene in the transconjugant caused assimilation of glucose to the synthesized cell carbon, but only to a limited extent and in a restricted pattern. Since the fixation of CO2 ha ...
P D G E
P D G E

... the likely underlying structure. The following data characteristics are typical of the gene expression dataset: Measurement accuracy of mRNA expression levels depends on the experimental design and rigour. While design of experiments is not a specific focus of this chapter, a good design minimises ...
Lecture 9
Lecture 9

... •Though most cells in an organism contain the same genes, not all of the genes are used in each cell. •Some genes are turned on, or "expressed" when needed in particular types of cells. •Microarray technology allows us to look at many genes at once and determine which are expressed in a particular c ...
Full Text
Full Text

... The POB provides gene-order and synteny visualization capabilities of orthologous genes and their functional annotations. For any given gene, the user can infer its orthologs in different plant species through a highly responsive web interface that provides integrated, interactive, and interconnecte ...
Normalization between a pair of arrays
Normalization between a pair of arrays

... •Though most cells in an organism contain the same genes, not all of the genes are used in each cell. •Some genes are turned on, or "expressed" when needed in particular types of cells. •Microarray technology allows us to look at many genes at once and determine which are expressed in a particular c ...
Slide 1
Slide 1

... Pre-nominal arguments are undergoer by ratio of 2.5:1 For predicates with agent and patient, post/post and pre/post patterns predominate, but others are common as well ...
TregouetD_EGEE3-presentation
TregouetD_EGEE3-presentation

... GWAS' main limits Enabling Grids for E-sciencE ...
Figure 15 - GEP Community Server
Figure 15 - GEP Community Server

... Download tool, we are ready to search for motifs that are enriched in this collection of sequences. Among the plethora of motif discovery tools that are publicly available, the MEME suite is one of the most popular solutions (BAILEY et al. 2009). In this walkthrough, we will use the web-based MEME i ...
Parent organism - Office of the Gene Technology Regulator
Parent organism - Office of the Gene Technology Regulator

... that enables visual identification of plant tissues in which it is being expressed. Short regulatory sequences that control expression of the genes are also present in the genetically modified cottons. These sequences are derived from the cauliflower mosaic virus, figwort mosaic virus, Agrobacterium ...
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics
Pisum Genetics Volume 26 1994 Preface 1 PGA "Pisum Genetics

... with essential details and references to techniques, a results section and a discussion section interpreting the results and integrating findings with those of other workers. Section headings are not obligatory. Conclusions should be justified, where applicable, by appropriate statistical analysis. ...
Evolution of genetic and genomic features unique to the human
Evolution of genetic and genomic features unique to the human

... 1990s permitted the evaluation of large-scale structural changes between humans and great apes that were not visible with conventional banding techniques12,13. More recently, these studies were aided by interspecies bacterial artificial chromosome (BAC)-based array-based comparative genomic hybridiz ...
Answers Activity 23.1 A Quick Review of Hardy
Answers Activity 23.1 A Quick Review of Hardy

... 8. Is it possible for a population’s genotype frequencies to change from one generation to the next but for its gene (allele) frequencies to remain constant? Explain by providing an example. There are a number of ways that this is possible. Here is one example of how it could occur: Assume inbreedin ...
Novel Molecular Methods for Discovery and Engineering of
Novel Molecular Methods for Discovery and Engineering of

... (Arnold, 2001; Daniel, 2001). More recently, many single genes, such as those coding for cellulolytic enzymes (Handelsman, 2004) and for chitinases (Cottrell, et al, 1999, 2000), have been successfully collected from environments and expressed by using this metagenomics approach. In spite of the pot ...
Expanding the `central dogma`: the regulatory role of
Expanding the `central dogma`: the regulatory role of

... protein complex. siRNAs bind to mRNA with perfect bp homology causing mRNA degradation. Synthesized double-stranded RNA introduced into the cell may be processed in a manner similar to endogenous siRNA and used to ‘silence’ a gene of interest. The mechanism where double-stranded RNA is processed to ...
Y chromosome: Structure and Biological Functions
Y chromosome: Structure and Biological Functions

... indirectly, via effects on testis development and ...
Acidaminococcus fermentans type strain (VR4T)
Acidaminococcus fermentans type strain (VR4T)

... the genus Acidaminococcus and the type strains of the other genera within the family Acidaminococcaceae. The tree was inferred from 1,348 aligned characters [10,11] of the 16S rRNA gene sequence under the maximum likelihood criterion [12] and rooted with the type strain of Anaerococcus prevotii, a m ...
Chromatin Remodeling - Molecular Pharmacology
Chromatin Remodeling - Molecular Pharmacology

... Molecular Pharmacology Fast Forward. Published on May 25, 2006 as DOI: 10.1124/mol.106.027078 This article has not been copyedited and formatted. The final version may differ from this version. ...
Centronuclear Myopathy Testing for Families
Centronuclear Myopathy Testing for Families

... X-linked myotubular myopathy is one type of CNM. Babies with X-linked myotubular myopathy (XLMTM) generally have low muscle tone, feeding and breathing problems, and developmental delay. XLMTM is usually only seen in boys. Females may carry a mutation in the gene for XLMTM, but they usually do not h ...
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