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LETTER Insertion DNA Promotes Ectopic Recombination during
LETTER Insertion DNA Promotes Ectopic Recombination during

... (fig. 2d), and low rates (0.26 on average in table 2) of somatic recombination between the asymmetric and the symmetric DNA were observed. These results indicated that the full-stained plants are less likely to be products of somatic recombination. Unlike meiotic division, somatic cell division lack ...
Single-step generation of rabbits carrying a targeted allele of the
Single-step generation of rabbits carrying a targeted allele of the

... affinity, and fused FokI nucleases generate a DSB; subsequently, error-prone nonhomologous end joining results in small insertions or deletions (indels). However, even though several methods such as Golden Gate assembly [4] or the Platinum Gate system [18] have been developed to decrease the steps, ...
Document
Document

... • Heredity: passing of traits from parent to child • Patterns of relatedness can help predict offspring characteristics ...
1.5MB - Whitehead Institute for Biomedical Research
1.5MB - Whitehead Institute for Biomedical Research

... – We now recognize this inheritance as being carried by variation in DNA ...
Characterization of the IEll0 Gene of Herpes Simplex Virus Type 1
Characterization of the IEll0 Gene of Herpes Simplex Virus Type 1

... gene encoding the immediate early protein IE 110, which is involved in transcriptional activation of later virus genes. The locations of the 5' and 3' termini of IE110 mRNA, together with the positions of two introns, were identified. Examination of the DNA sequence suggested that translation starts ...
Annotation
Annotation

... Annotating the Genome of a Bacteriophage – Part 2 Armed with all the information you have from part 1 (you have those printouts in front of you, right?), you’re ready to start calling genes. Stops are stops, so you can rest assured that when you run into an asterisk, you are at the end of that gene. ...
Using mouse genetics to understand human disease
Using mouse genetics to understand human disease

... – We now recognize this inheritance as being carried by variation in DNA ...
Chapter 12 Patterns of Inheritance
Chapter 12 Patterns of Inheritance

... color (Pp), what is the probability of the offspring being a heterozygote? There are two ways in which a heterozygote may be produced: the dominant allele (P) may be in the egg and the recessive allele (p) in the sperm, or the dominant allele may be in the sperm and the recessive in the egg. Consequ ...
Name - gcisd
Name - gcisd

... 1. The basic concepts of heredity were worked out in the mid 1800s by the Austrian monk __________________________. 2. In crosses with organisms showing pairs of contrasting traits, one trait is usually ______________, while the other trait is ________________. 3. An organism with two like genes for ...
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate

... JC 2002). In addition, genes affecting CL/P can be either autosomal recessive (50%), autosomal dominant (40%), or sex linked (10%) (Schutte and Murray. 1999). Pre-natal development of the craniofacial tissue begins at four weeks into the gestation period. It is also a period that is highly sensitiv ...
Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene
Signatures of Selection in the Human Olfactory Receptor OR5I1 Gene

... the OR. These results are compatible with positive selection having modeled the pattern of variation found in the OR5I1 gene and with a relatively ancient, mild selective sweep predating the ‘‘Out of Africa’’ expansion of modern humans. ...
Cis-Regulatory Timers for Developmental Gene
Cis-Regulatory Timers for Developmental Gene

... (ChIP) assays showed direct binding of the endogenous Bra protein to early- and middle-onset CRMs but not to the late-onset CRM in tailbud embryos. Thus, it appears that Bra controls late-onset gene expression indirectly by a ‘‘relay’’ mechanism in which earlyand/or middle-onset transcription regul ...
Guide to 2nd Drosophila discussion
Guide to 2nd Drosophila discussion

... decades, the observations stood as an enigma that defied normal views of how genes functioned. It is now commonly thought that close alignment of the homologous chromosomes in interphase allows the “cis” acting regulatory sequences to act in trans on the promoter of the homolog. Thus, mutations in “ ...
Document
Document

... Familial Neoplastic Syndrome Lymphoproliferative Disorder Molecular Disease Neoplasm Neoplasm by Morphology Neoplasm by Site Neoplasm by Special Category Neoplasm by Disease NEC Non-Neoplastic Disease, Syndrome, or Condition Precancerous Condition ...
Mendel`s First Law of Genetics (Law of Segregation)
Mendel`s First Law of Genetics (Law of Segregation)

... 2. Each parent has a gene pair in each cell for each trait studied. The F1 from a cross of two pure lines contains one allele for the dominant phenotype and one for the recessive phenotype. These two alleles comprise the gene pair. 3. One member of the gene pair segregates into a gamete, thus each g ...
Case Report Section
Case Report Section

... harboring t(2;11) was the homeobox genes HOXD13 in all case, and HOXD11 in one patient (Table 1). The NUP98-HOXD13 and NUP98-HOXD11 fusion transcripts were detected in bone marrow of these patients, respectively. In a mouse model, studies have shown that NUP98-HOXD13 transgenic mice developed MDS si ...
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten

... ABSTRACT One of resistance mechanisms to ciprofloxacin shown by bacterium Porphyromonas gingivalis isolated from periodontitis patients is mutations of genes through changes in DNA topoisomerase. Ciprofloxacin is an effective antimicrobial for Gram-negative bacteria effectively used for clinical inf ...
Name - cloudfront.net
Name - cloudfront.net

... when alleles are not completely dominant or recessive, when a particular gene has more than two alleles, or when a single gene produces multiple phenotypes. 18. Contrast complete dominance, incomplete dominance, and co-dominance. The Relationship Between Dominance and Phenotype We’ve now seen that t ...
Roots: The origins of molecular genetics: One gene, one enzyme
Roots: The origins of molecular genetics: One gene, one enzyme

... after he had passed from the scene and after his work had been repeated independently by others. In Garrod’s case, at least, it is clear that his discoveries came too early to be appreciated. In 1909, the year the word ‘gene’ was first used, genes were abstractions about which little was known beyon ...
The rfb cluster, which encodes functions involved in assembling the
The rfb cluster, which encodes functions involved in assembling the

... mpl, encoding murein peptide ligase, also involved in peptidoglycan metabolism, is mutated in SPA 8. The rfb cluster, which encodes functions involved in assembling the O-antigen, has a precise triplication in Paratyphi A, similar to repeats in this region reported for other Paratyphi A strains 9. A ...
Gregor Mendel - BEHS Science
Gregor Mendel - BEHS Science

... simply means that during gamete formation, allelic pairs that code for different traits assort independent of each other ...
Clustering Time-Series Gene Expression Data Using Smoothing
Clustering Time-Series Gene Expression Data Using Smoothing

...  We use splines for continuous representations, as ...
genetic problems
genetic problems

... it be white? List the genotypes of all the animals mentioned in this problem. 3. In dogs, wire hair is due to a dominant gene, smooth hair to its recessive allele. Two wire-haired dogs produce a male pup which is wire-haired. To find out most quickly whether he carries the gene for smooth hair, he s ...
Hypergeometric Tests for Gene Lists
Hypergeometric Tests for Gene Lists

... Back to the question Are there any GO terms that have a larger than expected subset of our selected genes in their annotation list? If so, these GO terms will give us insight into the functional characteristics of the gene list. The common test is for over representation, but one can also test for ...
Genotype
Genotype

... Fisher et al., (2007) Nucleic Acids Research ...
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Gene desert

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