CAP5510 - Bioinformatics - UF CISE
... science, and information technology merge into a single discipline. The ultimate goal of the field is to enable the discovery of new biological insights as well as to create a global perspective from which unifying principles in biology can be discerned. There are three important sub-disciplines wit ...
... science, and information technology merge into a single discipline. The ultimate goal of the field is to enable the discovery of new biological insights as well as to create a global perspective from which unifying principles in biology can be discerned. There are three important sub-disciplines wit ...
DNA and Cell Division
... information essential to life processes. Genetic information provides for continuity of life and, in most cases, this information is passed from parent to offspring via DNA. The double-stranded structure of DNA provides a simple and elegant solution for the transmission of heritable information to t ...
... information essential to life processes. Genetic information provides for continuity of life and, in most cases, this information is passed from parent to offspring via DNA. The double-stranded structure of DNA provides a simple and elegant solution for the transmission of heritable information to t ...
DNA,Rep,RNA,Trans pp
... Transcription – making mRNA 1. RNA polymerase (an enzyme) separates the DNA by breaking the hydrogen bonds (DNA unzips) 2. RNA polymerase brings in RNA nucleotides to bond with their complimentary bases along one side of the DNA molecule 3. RNA polymerase drops off, mRNA moves away, DNA molecule c ...
... Transcription – making mRNA 1. RNA polymerase (an enzyme) separates the DNA by breaking the hydrogen bonds (DNA unzips) 2. RNA polymerase brings in RNA nucleotides to bond with their complimentary bases along one side of the DNA molecule 3. RNA polymerase drops off, mRNA moves away, DNA molecule c ...
Gel electrophoresis - University of California, Santa Barbara
... translated into amino acid sequences • The “words” of the DNA “language” are triplets of bases called codons – 3 bases or nucleotides make one codon – Each codon specifies an amino acid – The codons in a gene specify the amino acid sequence of a polypeptide ...
... translated into amino acid sequences • The “words” of the DNA “language” are triplets of bases called codons – 3 bases or nucleotides make one codon – Each codon specifies an amino acid – The codons in a gene specify the amino acid sequence of a polypeptide ...
Mutations
... codon positions may have little or no effect on gene function. These mutations are called silent (if the amino acid is unchanged) or neutral (if the change has no effect). ...
... codon positions may have little or no effect on gene function. These mutations are called silent (if the amino acid is unchanged) or neutral (if the change has no effect). ...
Heredity & Genetics
... The cause of albinism is a mutation in one of several genes involved in the production of melanin. A mutation may result in no melanin production at all or a significant decline in the amount of melanin. In most types of albinism, a person must inherit two copies of a mutated gene — one from each pa ...
... The cause of albinism is a mutation in one of several genes involved in the production of melanin. A mutation may result in no melanin production at all or a significant decline in the amount of melanin. In most types of albinism, a person must inherit two copies of a mutated gene — one from each pa ...
DNA, RNA, & Protein Synthesis
... from the mRNA codon • tRNA molecules bring the amino acids in the correct order according to the codon – Every 3 bases codes for a particular amino acid – Look up the codon on page 303 of textbook to find amino acid • Amino acid sequence determines the type of protein ...
... from the mRNA codon • tRNA molecules bring the amino acids in the correct order according to the codon – Every 3 bases codes for a particular amino acid – Look up the codon on page 303 of textbook to find amino acid • Amino acid sequence determines the type of protein ...
Cancer
... oncogenes, tumor-suppressor genes and stability genes Unlike diseases such as cystic fibrosis or muscular dystrophy, wherein mutations in one gene can cause disease, no single gene defect 'causes' cancer. Mammalian cells have multiple safeguards to protect them against the potentially lethal effects ...
... oncogenes, tumor-suppressor genes and stability genes Unlike diseases such as cystic fibrosis or muscular dystrophy, wherein mutations in one gene can cause disease, no single gene defect 'causes' cancer. Mammalian cells have multiple safeguards to protect them against the potentially lethal effects ...
the synthetic theory of evolution - e
... Mendel’s work was appreciated as pioneering, but only in retrospect, after geneticist botanists Hugo de Vries, Carl Correns and Eric von Tschermak at the beginning of the 1900s, and William Bateson soon after, had independently rediscovered his (from gene to function) findings. These had never suffe ...
... Mendel’s work was appreciated as pioneering, but only in retrospect, after geneticist botanists Hugo de Vries, Carl Correns and Eric von Tschermak at the beginning of the 1900s, and William Bateson soon after, had independently rediscovered his (from gene to function) findings. These had never suffe ...
Classify the following genetic disorders as being caused by addition
... copies of the sickle cell gene, one from each parent. The sickle cell gene makes abnormal hemoglobin, called Hemoglobin-S. In sickle cell anemia, the abnormal hemoglobin (Hemoglobin-S) sticks together when it gives up its oxygen to the tissues. These clumps cause red blood cells to become stiff and ...
... copies of the sickle cell gene, one from each parent. The sickle cell gene makes abnormal hemoglobin, called Hemoglobin-S. In sickle cell anemia, the abnormal hemoglobin (Hemoglobin-S) sticks together when it gives up its oxygen to the tissues. These clumps cause red blood cells to become stiff and ...
gaurav narale - University of California San Diego
... Software Development to design, develop and implement applications. Written approx. 20000 lines of code to design front-end back-end applications, analyze and process scientific data and generate customized output in different visual formats. Masters in Chemical Engineering with 2+ years of extens ...
... Software Development to design, develop and implement applications. Written approx. 20000 lines of code to design front-end back-end applications, analyze and process scientific data and generate customized output in different visual formats. Masters in Chemical Engineering with 2+ years of extens ...
ForwardGeneticsMapping2012
... -Go back to previously identified recombinants (1 on left, 5 on right) -Use new markers to map recombination events e.g. 46T7 has allele of “strain 2”, so recombination is b/w 46T7 and oep ...
... -Go back to previously identified recombinants (1 on left, 5 on right) -Use new markers to map recombination events e.g. 46T7 has allele of “strain 2”, so recombination is b/w 46T7 and oep ...
2015-04
... duplication of chromosome region 16p13.3 detected by SNP-array analysis. In addition, myopia, microcephaly and growth retardation were observed. The causal 16p13.3 duplication is one of the smallest reported so far, and includes the CREB binding protein gene (CREBBP, MIM 600140), whose haploinsuffic ...
... duplication of chromosome region 16p13.3 detected by SNP-array analysis. In addition, myopia, microcephaly and growth retardation were observed. The causal 16p13.3 duplication is one of the smallest reported so far, and includes the CREB binding protein gene (CREBBP, MIM 600140), whose haploinsuffic ...
Unit 5: Gene Expression and Mutation Genetics 2013
... ____________________________________ provides a practical application of microRNAs because certain microRNAs are more or less abundant in cancer cells than in healthy ones ...
... ____________________________________ provides a practical application of microRNAs because certain microRNAs are more or less abundant in cancer cells than in healthy ones ...
Gene Therapy for Eye Disease
... involves injecting the virus under the retina, producing a temporary retinal detachment • Recovery time is usually rapid and it is often possible to go home the same day • Quality of sight is reduced temporarily until recovery is complete, which is usually expected to take a few weeks. ...
... involves injecting the virus under the retina, producing a temporary retinal detachment • Recovery time is usually rapid and it is often possible to go home the same day • Quality of sight is reduced temporarily until recovery is complete, which is usually expected to take a few weeks. ...
Evolution of Development (EvoDevo) •Development is the process
... 1. Homeotic genes turn on transcription of groups of genes to make structures such as legs, wings, antennae, etc. 2. Originally identified through mutations that cause dramatic changes in body appearance. 3. Homeotic gene products are homeodomain-type DNA binding proteins, regulating gene expression ...
... 1. Homeotic genes turn on transcription of groups of genes to make structures such as legs, wings, antennae, etc. 2. Originally identified through mutations that cause dramatic changes in body appearance. 3. Homeotic gene products are homeodomain-type DNA binding proteins, regulating gene expression ...
linkage
... Monohybrid cross 3:1 Test cross 1:1 Dihybrid cross 9:3:3:1 Test cross 1:1:1:1 These are due to the fact that genes are on different chromosomes and they segregate when the gametes are formed. ...
... Monohybrid cross 3:1 Test cross 1:1 Dihybrid cross 9:3:3:1 Test cross 1:1:1:1 These are due to the fact that genes are on different chromosomes and they segregate when the gametes are formed. ...
Study of Holocaust survivors finds trauma passed on to children
... smoking, diet and stress can affect the genes of your children and possibly even grandchildren. The idea is controversial, as scientific convention states that genes contained in DNA are the only way to transmit biological information between generations. However, our genes are modified by the envir ...
... smoking, diet and stress can affect the genes of your children and possibly even grandchildren. The idea is controversial, as scientific convention states that genes contained in DNA are the only way to transmit biological information between generations. However, our genes are modified by the envir ...
DNA Test Review What are the four nucleotides in DNA? Which
... 12. Why is tRNA important in translation? 13. What is the difference between DNA and RNA? 14. How many amino acids does this DNA sequence represent: TAAAGGCCC? 15. How can only 20 amino acids make thousands of proteins? 16. What is the ratio of A:T and C:G? 17. Why is DNA replication called semicons ...
... 12. Why is tRNA important in translation? 13. What is the difference between DNA and RNA? 14. How many amino acids does this DNA sequence represent: TAAAGGCCC? 15. How can only 20 amino acids make thousands of proteins? 16. What is the ratio of A:T and C:G? 17. Why is DNA replication called semicons ...
Diagnostic perspective in general practice
... nucleotides of the human genome have been sequenced and the knowledge of their organisation into the known 30 000–35 000 (possibly 100 000) functional units or genes continues to become more sophisticated.2 The genome project has commenced mapping out ‘single nucleotide polymorphisms’ (SNPs) as sign ...
... nucleotides of the human genome have been sequenced and the knowledge of their organisation into the known 30 000–35 000 (possibly 100 000) functional units or genes continues to become more sophisticated.2 The genome project has commenced mapping out ‘single nucleotide polymorphisms’ (SNPs) as sign ...
Reverse Genetics -
... negative” gene products (primarily used in cell culture) • Based on definition of Dominant Negative (Dn) from Ira Herskowitz [Nature, 1987. 329:219-222] should act in the same phenotypic direction as loss of function. • However, lots of caveats to this method. - Biochemical mode of action of Dn-pr ...
... negative” gene products (primarily used in cell culture) • Based on definition of Dominant Negative (Dn) from Ira Herskowitz [Nature, 1987. 329:219-222] should act in the same phenotypic direction as loss of function. • However, lots of caveats to this method. - Biochemical mode of action of Dn-pr ...
4 . The imino tautomer of adenine can pair with cytosine
... Nitrous acid (HNO2) hydrolyzes amino groups on bases via diazotization. Adenine is deaminated to hypoxanthine, cytosine to uracil, and guanine to xanthine. Hypoxanthine pairs with cytosine, inducing a mutation of A-T to G-C. It is likely that mutations in DNA repair genes will lead to the accumulati ...
... Nitrous acid (HNO2) hydrolyzes amino groups on bases via diazotization. Adenine is deaminated to hypoxanthine, cytosine to uracil, and guanine to xanthine. Hypoxanthine pairs with cytosine, inducing a mutation of A-T to G-C. It is likely that mutations in DNA repair genes will lead to the accumulati ...
Bio3124 Lecture 10
... - Operon is off when LacI binds to the operator. - Operon is on when allolactose binds to LacI; cAMPCRP are bound to the promoter (and there is no glucose around). ● The tryptophan operon is regulated by repression and attenuation (premature transcript termination). ...
... - Operon is off when LacI binds to the operator. - Operon is on when allolactose binds to LacI; cAMPCRP are bound to the promoter (and there is no glucose around). ● The tryptophan operon is regulated by repression and attenuation (premature transcript termination). ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.