Medical Genetics 2013
... A. A chromosome translocation fusing portions of the oncogene and another cellular gene B. Inactivation of an oncogene by epigenetic modification C. A point mutation altering the function of the oncogene protein product D. Capture of the oncogene sequence by a retrovirus E. Amplification of an oncog ...
... A. A chromosome translocation fusing portions of the oncogene and another cellular gene B. Inactivation of an oncogene by epigenetic modification C. A point mutation altering the function of the oncogene protein product D. Capture of the oncogene sequence by a retrovirus E. Amplification of an oncog ...
TRASK Zool 3200: Cell Biology Exam 2
... which region is responsible for the observed tissue‐specific expression, and create mutations in the promoter to determine the function of each of these regions. The data you obtain is shown in the figure below—if the site is missing, it is mutated such that it cannot bind its corresponding transc ...
... which region is responsible for the observed tissue‐specific expression, and create mutations in the promoter to determine the function of each of these regions. The data you obtain is shown in the figure below—if the site is missing, it is mutated such that it cannot bind its corresponding transc ...
Fall 2014
... d. different in that binary fission occurs in cells with many chromosomes, whereas mitosis occurs in cells with just one chromosome. e. None of the above is true. 31. What was the effect of crossing over in the “reptilobird” portion of the Fun with Genetics lab? a. It helped each zygote grow into a ...
... d. different in that binary fission occurs in cells with many chromosomes, whereas mitosis occurs in cells with just one chromosome. e. None of the above is true. 31. What was the effect of crossing over in the “reptilobird” portion of the Fun with Genetics lab? a. It helped each zygote grow into a ...
Origin and Nature of Genetic Variation
... • A single bp change involving intron /exon splice sites or cryptic sites. • Beta-Thalassemia syndromes have mutations that alter the normal splice acceptor or donor sites • Activate cryptic splice sites that compete with the correct site. • A splicing mutation can also occur secondary to deletion o ...
... • A single bp change involving intron /exon splice sites or cryptic sites. • Beta-Thalassemia syndromes have mutations that alter the normal splice acceptor or donor sites • Activate cryptic splice sites that compete with the correct site. • A splicing mutation can also occur secondary to deletion o ...
05_GENE_EXPRESSION
... Made as subunits in the nucleolus rRNA provides the platform from protein synthesis ...
... Made as subunits in the nucleolus rRNA provides the platform from protein synthesis ...
Linked Genes and Crossing Over
... 1. Linked genes are genes that are inherited together because they are on the same chromosome. *** Do not get this confused with sex-linked genes which are genes that are only carried on a single sex chromosome. 2. Thomas Hunt Morgan discovered that the expected 9:3:3:1 phenotypic ratio in a dihybri ...
... 1. Linked genes are genes that are inherited together because they are on the same chromosome. *** Do not get this confused with sex-linked genes which are genes that are only carried on a single sex chromosome. 2. Thomas Hunt Morgan discovered that the expected 9:3:3:1 phenotypic ratio in a dihybri ...
A New Way of Classifying Life?
... combinations are produced when organisms pass down genetic information vertically from one generation to the next. When these combinations are subjected to selective pressures, vertical evolution occurs. Horizontal gene transmission occurs when organisms within the same generation swap genetic mater ...
... combinations are produced when organisms pass down genetic information vertically from one generation to the next. When these combinations are subjected to selective pressures, vertical evolution occurs. Horizontal gene transmission occurs when organisms within the same generation swap genetic mater ...
Soybean (Glycine max L.) Nuclear DNA Contains
... Chloroplasts are considered to be endosymbionts of prokaryotic origin having invaded in an evolutionary past nucleated heterotrophic cells. During evolution parts of the. organellar genome were transposed to and successfully integrated in the nuclear genome ,i.e., structure and function of the photo ...
... Chloroplasts are considered to be endosymbionts of prokaryotic origin having invaded in an evolutionary past nucleated heterotrophic cells. During evolution parts of the. organellar genome were transposed to and successfully integrated in the nuclear genome ,i.e., structure and function of the photo ...
TASSEL
... Stretches of DNA that are closely linked to the genes that underlie the trait. QTLs can be molecularly identified (for example, with PCR or AFLP) to help map regions of the genome. This can be an early step in identifying and sequencing these genes. Their phenotypes typically vary along a continuous ...
... Stretches of DNA that are closely linked to the genes that underlie the trait. QTLs can be molecularly identified (for example, with PCR or AFLP) to help map regions of the genome. This can be an early step in identifying and sequencing these genes. Their phenotypes typically vary along a continuous ...
III. Mechanisms contributing to antibody diversity
... B. Allelic exclusion is the expression, in a single cell, of only one allele at a particular locus 1. Two or more alleles frequently exist at the genetic loci for the various components of H and L chains 2. Because of allelic exclusion, only one H chain and one L chain gene can be expressed in any g ...
... B. Allelic exclusion is the expression, in a single cell, of only one allele at a particular locus 1. Two or more alleles frequently exist at the genetic loci for the various components of H and L chains 2. Because of allelic exclusion, only one H chain and one L chain gene can be expressed in any g ...
Reproduction
... • Genotype + Environment = Phenotype • Example – Genetically similar animals fed different levels of nutrition – Are they going to perform different? ...
... • Genotype + Environment = Phenotype • Example – Genetically similar animals fed different levels of nutrition – Are they going to perform different? ...
some molecular basics
... actinin, vav and spectrin. In human ORF1 (IQGAP1), the Mp domain is homologous to the fly muscle protein mp20, and the GTPase activator is a rasGAP domain. The Y domain, shared by Yo61 and Ykb2, has no known function. Sizes of all proteins and domains are not to scale. ...
... actinin, vav and spectrin. In human ORF1 (IQGAP1), the Mp domain is homologous to the fly muscle protein mp20, and the GTPase activator is a rasGAP domain. The Y domain, shared by Yo61 and Ykb2, has no known function. Sizes of all proteins and domains are not to scale. ...
Natural selection
... Natural selection, genetic drift, and gene flow can alter allele frequencies in a population The three main causes of microevolutionary ...
... Natural selection, genetic drift, and gene flow can alter allele frequencies in a population The three main causes of microevolutionary ...
Mutations Justified True or False
... mutation in the gene is changed in the sperm or the egg. They don’t need to be passed for a mutation to occur. Unless the organism is the first to have the mutated gene. Then in order to see the mutation the organism must have an offspring. But still then the mutation might not be ...
... mutation in the gene is changed in the sperm or the egg. They don’t need to be passed for a mutation to occur. Unless the organism is the first to have the mutated gene. Then in order to see the mutation the organism must have an offspring. But still then the mutation might not be ...
Document
... carCinogenic polycyclic aromatic hydrocarbons is believed to involve alkylation of DNA. A series of adenosines and 2'-deoxyadenosine substituted at N6 by related ara1ky1s of differing carCinogenic potential has been prepared. We report here the crystal structure determinations of four of these compo ...
... carCinogenic polycyclic aromatic hydrocarbons is believed to involve alkylation of DNA. A series of adenosines and 2'-deoxyadenosine substituted at N6 by related ara1ky1s of differing carCinogenic potential has been prepared. We report here the crystal structure determinations of four of these compo ...
Presentación de PowerPoint
... 4. The key role of imidazolides in prebiotic chemistry and in biological catalysis suggests a connection between the chemical constituents of the RNA World and the emergence of the first proteins. ...
... 4. The key role of imidazolides in prebiotic chemistry and in biological catalysis suggests a connection between the chemical constituents of the RNA World and the emergence of the first proteins. ...
Chapter 21
... • For example, it is estimated that the nematode C. elegans has 100 Mb and 20,000 genes, while Drosophila has 165 Mb and 13,700 genes • Vertebrate genomes can produce more than one polypeptide per gene because of alternative splicing of RNA transcripts ...
... • For example, it is estimated that the nematode C. elegans has 100 Mb and 20,000 genes, while Drosophila has 165 Mb and 13,700 genes • Vertebrate genomes can produce more than one polypeptide per gene because of alternative splicing of RNA transcripts ...
Mutations
... fragments (= you can clone smaller DNA fragments in plasmid vectors, but large fragments in BAC’s and very large fragments in YAC vectors) Therefore very good for generating tiling libraries ...
... fragments (= you can clone smaller DNA fragments in plasmid vectors, but large fragments in BAC’s and very large fragments in YAC vectors) Therefore very good for generating tiling libraries ...
Identification and Characterization of a Novel Human Testis
... the exons were performed using the BLASTP program and the GenBank databases (12). Structure analysis studies. Multiple alignment was performed using the Clustal X multiple alignment program (16). Phylogenetic studies were performed using the Phylip software package (17). Distance matrix analysis was ...
... the exons were performed using the BLASTP program and the GenBank databases (12). Structure analysis studies. Multiple alignment was performed using the Clustal X multiple alignment program (16). Phylogenetic studies were performed using the Phylip software package (17). Distance matrix analysis was ...
Quantitative Genetics and Whole Genome Approaches
... 2) These loci are primarily associated with a much reduced effect on the disease (low risk) and much higher frequencies in the populations 3) A seeming majority map to regions that are non-coding (i) Are they regulatory? Epigenetic or eQTL? 4) When we try to include these newly identified polymorphi ...
... 2) These loci are primarily associated with a much reduced effect on the disease (low risk) and much higher frequencies in the populations 3) A seeming majority map to regions that are non-coding (i) Are they regulatory? Epigenetic or eQTL? 4) When we try to include these newly identified polymorphi ...
gene_expression_info
... joined by peptide bonds. • Proteins are large polypeptides. • There are 20 different aa and their sequence determines the structure and function of the protein. • The sequence of bases in a DNA molecule determines the sequence of aa. • A gene is a length of DNA that codes for one (or more) polypepti ...
... joined by peptide bonds. • Proteins are large polypeptides. • There are 20 different aa and their sequence determines the structure and function of the protein. • The sequence of bases in a DNA molecule determines the sequence of aa. • A gene is a length of DNA that codes for one (or more) polypepti ...
The S RNA segment of tomato spotted wilt virus has an ambisense
... 1984; Salvato, 1989). To identify possible mRNA species corresponding to the nucleocapsid protein and the putative non-structural protein, Fig. 6 shows Northern blots of total RNA isolated from healthy and infected plants, hybridized to 32p-labelled probes. The probe corresponding to the ORF on the ...
... 1984; Salvato, 1989). To identify possible mRNA species corresponding to the nucleocapsid protein and the putative non-structural protein, Fig. 6 shows Northern blots of total RNA isolated from healthy and infected plants, hybridized to 32p-labelled probes. The probe corresponding to the ORF on the ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.