Molecular diversity of thermophilic bacteria isolated from Pasinler
... Abstract: The present study was conducted to determine the phenotypic and genotypic characterization of thermophilic bacteria isolated from Pasinler hot spring, Erzurum, Turkey. Fatty acid profiles, BOX PCR fingerprints, and 16S rDNA sequence data were used for the phenotypic and genotypic character ...
... Abstract: The present study was conducted to determine the phenotypic and genotypic characterization of thermophilic bacteria isolated from Pasinler hot spring, Erzurum, Turkey. Fatty acid profiles, BOX PCR fingerprints, and 16S rDNA sequence data were used for the phenotypic and genotypic character ...
Review Article RNA-Binding Proteins in Amyotrophic Lateral
... including R521C, R524S, R522G, and P525L, caused FUS mislocalization to the cytoplasm, in a manner dependent on the severity of the mutations in altering the integrity of the PY-NLS [35, 36]. Interestingly, the degree of cytoplasmic mislocalization was correlated with mean age of disease onset, with ...
... including R521C, R524S, R522G, and P525L, caused FUS mislocalization to the cytoplasm, in a manner dependent on the severity of the mutations in altering the integrity of the PY-NLS [35, 36]. Interestingly, the degree of cytoplasmic mislocalization was correlated with mean age of disease onset, with ...
PDF
... maximum tillering stage results in blighting of leaves, which eventually causes significant yield losses in severely infected fields ranging from 20 to 30%, but this can reach as high as 80% (Mew et al., 1993; Srinivasan and Gnanamanickam, 2005; Noh et al., 2007). Due to the ineffectiveness of chemi ...
... maximum tillering stage results in blighting of leaves, which eventually causes significant yield losses in severely infected fields ranging from 20 to 30%, but this can reach as high as 80% (Mew et al., 1993; Srinivasan and Gnanamanickam, 2005; Noh et al., 2007). Due to the ineffectiveness of chemi ...
Document
... The cDNA sequences encoding prolactin (PRL), somatolactin (SL) and insulin-like growth factor-I (IGF-I) genes of the yellow perch were obtained. Brain, pituitary, gill, heart, liver, stomach, kidney, spleen, muscle and gonad tissues were analyzed from both male and female adult yellow perch for sex- ...
... The cDNA sequences encoding prolactin (PRL), somatolactin (SL) and insulin-like growth factor-I (IGF-I) genes of the yellow perch were obtained. Brain, pituitary, gill, heart, liver, stomach, kidney, spleen, muscle and gonad tissues were analyzed from both male and female adult yellow perch for sex- ...
Slide 1
... Mutations that involve changes in one or a few nucleotides are known as point mutations because they occur at a single point in the DNA sequence. They generally occur during replication. If a gene in one cell is altered, the alteration can be passed on to every cell that develops from the original o ...
... Mutations that involve changes in one or a few nucleotides are known as point mutations because they occur at a single point in the DNA sequence. They generally occur during replication. If a gene in one cell is altered, the alteration can be passed on to every cell that develops from the original o ...
Solid Tumour Section Nervous system: Medulloblastoma Atlas of Genetics and Cytogenetics
... Isochromosome 17q has been observed in interphase nuclei using fluorescence in situ hybridization. This technique is used in particular when only a few metaphases are obtained or when only normal diploid cells are obtained in culture. ...
... Isochromosome 17q has been observed in interphase nuclei using fluorescence in situ hybridization. This technique is used in particular when only a few metaphases are obtained or when only normal diploid cells are obtained in culture. ...
Mechanisms and constraints shaping the evolution of body plan
... gene regulatory network (GRN) or directly of a regulatory network. Offspring inherits the genotype from a single parent. Mutations can build new or remove existing regulatory connections between genes, change their nature (activating or repressing gene expression) and strength, and in addition may aff ...
... gene regulatory network (GRN) or directly of a regulatory network. Offspring inherits the genotype from a single parent. Mutations can build new or remove existing regulatory connections between genes, change their nature (activating or repressing gene expression) and strength, and in addition may aff ...
Analysis of alternative splicing in Drosophila genetic
... 2.3 The application of genetic mosaics to analysis of alternative pre-mRNA splicing. A common issue in the analysis of reporters in whole organisms is that the effects of different genotypes must be inferred from comparison of reporter signals in tissues derived from separate individuals. Such comp ...
... 2.3 The application of genetic mosaics to analysis of alternative pre-mRNA splicing. A common issue in the analysis of reporters in whole organisms is that the effects of different genotypes must be inferred from comparison of reporter signals in tissues derived from separate individuals. Such comp ...
A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is
... new type of GATA-binding transactivator via binding to D1CONS.15 However, GAL4-EVI1 and GAL4-MDS1/EVI1 fusion proteins showed transcription repressor activity that was dependent on GAL4 DNA-binding capability.16 Moreover, EVI1 can bind to transcriptional repressor cofactors (adenovirus E1A C-termina ...
... new type of GATA-binding transactivator via binding to D1CONS.15 However, GAL4-EVI1 and GAL4-MDS1/EVI1 fusion proteins showed transcription repressor activity that was dependent on GAL4 DNA-binding capability.16 Moreover, EVI1 can bind to transcriptional repressor cofactors (adenovirus E1A C-termina ...
Statistical analysis of atomic contacts at RNA– protein
... Forty-five crystals of complexes between proteins and RNA molecules from the Protein Data Bank have been statistically surveyed for the number of contacts between RNA components (phosphate, ribose and the four bases) and amino acid side chains. Three groups of complexes were defined: the tRNA synthe ...
... Forty-five crystals of complexes between proteins and RNA molecules from the Protein Data Bank have been statistically surveyed for the number of contacts between RNA components (phosphate, ribose and the four bases) and amino acid side chains. Three groups of complexes were defined: the tRNA synthe ...
PowerPoint Presentation - No Slide Title
... • Static genetic information is stored in DNA • Genes are portions of DNA which are “transcribed” into mRNA • mRNA is “translated” by ribosomes into proteins • Proteins carry out the essential cellular functions: enzymatic, regulatory, structural Sanguinetti, 2011 ...
... • Static genetic information is stored in DNA • Genes are portions of DNA which are “transcribed” into mRNA • mRNA is “translated” by ribosomes into proteins • Proteins carry out the essential cellular functions: enzymatic, regulatory, structural Sanguinetti, 2011 ...
Opsin genes, cone photopigments, color vision, and color blindness
... hydrogen bonds. Adenine (A) conjoins with thymine (T) and guanine (G) with cytosine (C); no other combinations are possible. The base sequences can be divided into promoter, noncoding (intron), and coding (exon) sequences (see Fig. 1.3A). (i) Transcription unit: The term “transcription unit” is ofte ...
... hydrogen bonds. Adenine (A) conjoins with thymine (T) and guanine (G) with cytosine (C); no other combinations are possible. The base sequences can be divided into promoter, noncoding (intron), and coding (exon) sequences (see Fig. 1.3A). (i) Transcription unit: The term “transcription unit” is ofte ...
Extended Life-Span and Stress Resistance in Drosophila
... each gene, one inherited from each parent. • Using genetic engineering methods, it is possible to delete or otherwise alter one or both copies of a gene, so that the animal has either one or no working copy of the gene. • A mouse altered in this way is called a "knockout" mouse. ...
... each gene, one inherited from each parent. • Using genetic engineering methods, it is possible to delete or otherwise alter one or both copies of a gene, so that the animal has either one or no working copy of the gene. • A mouse altered in this way is called a "knockout" mouse. ...
Novel Ciliate Genetic Code Variants Including the Reassignment of
... Atkins JF, Miceli C, Hatfield DL, Baranov PV, Gladyshev VN, unpublished data). While the analysis revealed thousands of ribosomal frameshifting occurrences at TAA/TAG codons, it revealed no cases of stop codon readthrough that preserved the frame. As can be seen in figure 1, the density of TAA/TAG c ...
... Atkins JF, Miceli C, Hatfield DL, Baranov PV, Gladyshev VN, unpublished data). While the analysis revealed thousands of ribosomal frameshifting occurrences at TAA/TAG codons, it revealed no cases of stop codon readthrough that preserved the frame. As can be seen in figure 1, the density of TAA/TAG c ...
reprint - Oleg Igoshin
... metabolic pathway (Figure 2A), redundant catalysis of the same metabolic step (Figure 2B), catalysis of diverging reactions following a branch point in a metabolic pathway (Figure 2C), redundant transcriptional regulation of a downstream gene (Figure 2D), physical binding between two proteins (Figur ...
... metabolic pathway (Figure 2A), redundant catalysis of the same metabolic step (Figure 2B), catalysis of diverging reactions following a branch point in a metabolic pathway (Figure 2C), redundant transcriptional regulation of a downstream gene (Figure 2D), physical binding between two proteins (Figur ...
Evolution of codon usage bias in Drosophila
... subgenera Sophophora and Drosophila diverged from each other about 50 million years ago (7), so the avoidance of particular codons in Adh, namely AUA (isoleucine), GGG (glycine), and UUA (leucine), has persisted for a very long time. It is not the case that Drosophila simply cannot use these codons; ...
... subgenera Sophophora and Drosophila diverged from each other about 50 million years ago (7), so the avoidance of particular codons in Adh, namely AUA (isoleucine), GGG (glycine), and UUA (leucine), has persisted for a very long time. It is not the case that Drosophila simply cannot use these codons; ...
Noise in transcription negative feedback loops
... and the suppression of the noise by the negative feedback loop should be mainly owing to elimination of the fluctuations introduced by changes in the plasmid number. This would suggest that negative feedback loops do not suppress intrinsic noise, but rather eliminate external noise that might arise f ...
... and the suppression of the noise by the negative feedback loop should be mainly owing to elimination of the fluctuations introduced by changes in the plasmid number. This would suggest that negative feedback loops do not suppress intrinsic noise, but rather eliminate external noise that might arise f ...
RAPD mapping of three QTLs determining trichome - UvA-DARE
... trichomcs seems to be genetically regulated (Bachmann et al. 1987; Bachmann and Chambers 1990). Where they appear first on leaves of vegetative rosettes, they are restricted to the angles of the leaf teeth or to the abaxial (under) side of the leaf tip. Their appearance in these positions may be tra ...
... trichomcs seems to be genetically regulated (Bachmann et al. 1987; Bachmann and Chambers 1990). Where they appear first on leaves of vegetative rosettes, they are restricted to the angles of the leaf teeth or to the abaxial (under) side of the leaf tip. Their appearance in these positions may be tra ...
The Johns Hopkins University - American University of Beirut
... about some of the proteins they found similarities to. • Heard on about a disease gene that was recently discovered, and you want to know more about it. • Want to build a dataset for local blast searches. • A colleague wants you to do an alignment of all sequences from a given protein family. Lectur ...
... about some of the proteins they found similarities to. • Heard on about a disease gene that was recently discovered, and you want to know more about it. • Want to build a dataset for local blast searches. • A colleague wants you to do an alignment of all sequences from a given protein family. Lectur ...
(base) sequence of the genome might reflect biological information
... of chromosome II was enlarged to 990 nt (Figure 2(c), 648 ~ 1,638), or 1,584 nt (Figure 2(d), 54 ~ 1,638), respectively. That is, the base sequence of the complete ATP1 gene had self-similarity to the gene-position on chromosome II. Other genes of S. cerevisiae were highly homologous with the gene-p ...
... of chromosome II was enlarged to 990 nt (Figure 2(c), 648 ~ 1,638), or 1,584 nt (Figure 2(d), 54 ~ 1,638), respectively. That is, the base sequence of the complete ATP1 gene had self-similarity to the gene-position on chromosome II. Other genes of S. cerevisiae were highly homologous with the gene-p ...
using the crispr/cas9 gene editing tool to develop a cure for
... genetics as a whole. With CRISPR, this has all changed. In October 2015, researchers at Harvard University were able to successfully alter 62 different genes simultaneously in pig embryos with the use of CRISPR, and the whole process took less than a year [6]. This ability provides an opportunity to ...
... genetics as a whole. With CRISPR, this has all changed. In October 2015, researchers at Harvard University were able to successfully alter 62 different genes simultaneously in pig embryos with the use of CRISPR, and the whole process took less than a year [6]. This ability provides an opportunity to ...
development, the Linker histone H1 is essential for Drosophila
... silencing of the Drosophila linker histone H1 gene. Two identical fragments of the H1 coding sequence (the first 600 bp) were inserted in opposite orientations on both sides of the first intron of the actin 5C gene in the pINT-1 vector. The expression of H1-specific dsRNA is driven by the GAL4-respo ...
... silencing of the Drosophila linker histone H1 gene. Two identical fragments of the H1 coding sequence (the first 600 bp) were inserted in opposite orientations on both sides of the first intron of the actin 5C gene in the pINT-1 vector. The expression of H1-specific dsRNA is driven by the GAL4-respo ...
Cambridge Workshop November 2008
... 1. Add relevant publications to FlyBase 2. Associate genes with uncurated publications 3. Flag data types in uncurated publications 4. Submit revisions to gene models 5. Work with FlyBase curators to improve specific areas 6. Annotate / clean up 'gene orphans’ 7. Use FlyBase symbols in your papers 8 ...
... 1. Add relevant publications to FlyBase 2. Associate genes with uncurated publications 3. Flag data types in uncurated publications 4. Submit revisions to gene models 5. Work with FlyBase curators to improve specific areas 6. Annotate / clean up 'gene orphans’ 7. Use FlyBase symbols in your papers 8 ...
How to measure chromatin modifications
... produces 21–22 bp sequence tags from the immunoprecipitated fragments; the sequence tags are concatenated, cloned into a sequencing vector and sequenced. About 20 to 30 short sequence tags of 21 bp can be generated from each sequencing reaction. The sequence tags can then be mapped to the genome to ...
... produces 21–22 bp sequence tags from the immunoprecipitated fragments; the sequence tags are concatenated, cloned into a sequencing vector and sequenced. About 20 to 30 short sequence tags of 21 bp can be generated from each sequencing reaction. The sequence tags can then be mapped to the genome to ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.