functional_enrichment_new - Baliga Lab at Institute for Systems
... common multiple testing correction techniques maybe overly conservative approaches if there are thousands or even more annotation terms involved in the analysis Genome Inform. 2005;16:106-115.; Nucleic Acids Research, 2009, Vol. 37, No. 1 1–13 ...
... common multiple testing correction techniques maybe overly conservative approaches if there are thousands or even more annotation terms involved in the analysis Genome Inform. 2005;16:106-115.; Nucleic Acids Research, 2009, Vol. 37, No. 1 1–13 ...
Integrated analysis of regulatory and metabolic networks
... framework can then be used to make phenotypic predictions that can be compared to experimental data. Frequently used constraint-based approaches include flux balance analysis (FBA) and regulated flux-balance analysis (rFBA) approach. ...
... framework can then be used to make phenotypic predictions that can be compared to experimental data. Frequently used constraint-based approaches include flux balance analysis (FBA) and regulated flux-balance analysis (rFBA) approach. ...
Missing Value Estimation for Gene Expression Profile Data
... of the observed values over that gene[5] . Case deletion procedures may bias the results if the remaining cases are unrepresentative of the entire sample. Because the same value is used to replace MVs in a given gene, both zero and mean substitutions will reduce the variance of the variable in quest ...
... of the observed values over that gene[5] . Case deletion procedures may bias the results if the remaining cases are unrepresentative of the entire sample. Because the same value is used to replace MVs in a given gene, both zero and mean substitutions will reduce the variance of the variable in quest ...
cognitive measures (set-shifting)
... affect phenotypes relevant to this disease. Treatment outcome will also be investigated in relation to genotypes and phenotypes. Preliminary results concerning Dopamine Receptor D2 (DRD2) gene are presented. ...
... affect phenotypes relevant to this disease. Treatment outcome will also be investigated in relation to genotypes and phenotypes. Preliminary results concerning Dopamine Receptor D2 (DRD2) gene are presented. ...
PDF
... cluster of genes or between clusters? What is the nature of the interaction between genes (e.g does gene A inhibit gene B)? To infer such finer relations from perturbed gene expression profiles we use the framework of Friedman et al. (2000). In this framework, we treat the measured expression leve ...
... cluster of genes or between clusters? What is the nature of the interaction between genes (e.g does gene A inhibit gene B)? To infer such finer relations from perturbed gene expression profiles we use the framework of Friedman et al. (2000). In this framework, we treat the measured expression leve ...
questionsCh12.doc
... 8. Anne Boleyn, King Henry VIII's second wife, was beheaded because she did not provide him with a son as an heir. Explain why King Henry should have blamed himself and not his wife. a. All of the sperm that males produce contain an X chromosome, so their genetic contribution to the child determines ...
... 8. Anne Boleyn, King Henry VIII's second wife, was beheaded because she did not provide him with a son as an heir. Explain why King Henry should have blamed himself and not his wife. a. All of the sperm that males produce contain an X chromosome, so their genetic contribution to the child determines ...
Gene Section TACC2 (transforming, acidic coiled-coil containing protein 2)
... terminates due to a C-T mutation in the cDNA generating a nonsense codon; the partial cDNA coding this open reading frame is identical to other TACC2 isoforms downstream of the nonsense codon, suggesting the mutation is a cloning artefact. Western blot analysis confirms the large ≈ 300 kDa isoforms ...
... terminates due to a C-T mutation in the cDNA generating a nonsense codon; the partial cDNA coding this open reading frame is identical to other TACC2 isoforms downstream of the nonsense codon, suggesting the mutation is a cloning artefact. Western blot analysis confirms the large ≈ 300 kDa isoforms ...
Lecture 14 Gene Regulation
... with the goal of increasing in mass and dividing. • Genes that are continuously expressed are constitutive genes or housekeeping genes. Examples include protein synthesis and glucose metabolism. ...
... with the goal of increasing in mass and dividing. • Genes that are continuously expressed are constitutive genes or housekeeping genes. Examples include protein synthesis and glucose metabolism. ...
Nucleic Acids Notes
... DNA flexibility depends on its sequence! • It is very important to be able to predict this dependence (still not fully solved problem). • What’s more flexible: AAAAA TTTTTT Or: GGGGGG CCCCCC A-T linked by 2 H-bonds, but G-C by 3. Less room to wiggle, so less flexible. ...
... DNA flexibility depends on its sequence! • It is very important to be able to predict this dependence (still not fully solved problem). • What’s more flexible: AAAAA TTTTTT Or: GGGGGG CCCCCC A-T linked by 2 H-bonds, but G-C by 3. Less room to wiggle, so less flexible. ...
lab9 - Java JAVAC
... Pigmented anterior of the iris – If you have pigment on the anterior and posterior of the iris, your eyes are green, brown, black and hazel. If you lack pigment on the anterior aspect of the iris, yours eyes are blue or grey. Pigmentation is dominant ...
... Pigmented anterior of the iris – If you have pigment on the anterior and posterior of the iris, your eyes are green, brown, black and hazel. If you lack pigment on the anterior aspect of the iris, yours eyes are blue or grey. Pigmentation is dominant ...
Separated Twins
... possibility of getting pregnant? • We could find a way to coexist with one another in a peaceful utopia? • What would you say to that? ...
... possibility of getting pregnant? • We could find a way to coexist with one another in a peaceful utopia? • What would you say to that? ...
Chapter 11 Intro to Genetics
... d. Chickens w/ black/white feathers 5. Multiple alleles a. Genes have more than 2 alleles b. Individual may inherit 2 alleles only c. Blood types have alleles A,B,O --combination can be AA, AO, BB, BO, AB, OO d. Eye color/hair color 6. Polygenic traits a. Inheritance of several genes --skin color ( ...
... d. Chickens w/ black/white feathers 5. Multiple alleles a. Genes have more than 2 alleles b. Individual may inherit 2 alleles only c. Blood types have alleles A,B,O --combination can be AA, AO, BB, BO, AB, OO d. Eye color/hair color 6. Polygenic traits a. Inheritance of several genes --skin color ( ...
speciation (formation of new species)
... The total of all the different genes in a population is called the gene pool. If a species is under no selective pressure, frequencies of individual alleles will stay the same from generation to generation. Genetic drift is the random increase or decrease in frequency of genetic sequences. Genetic d ...
... The total of all the different genes in a population is called the gene pool. If a species is under no selective pressure, frequencies of individual alleles will stay the same from generation to generation. Genetic drift is the random increase or decrease in frequency of genetic sequences. Genetic d ...
Translation
... ● Converts mRNA from transcription into protein (polypeptide) ● Codon- a sequence of 3 RNA nucleotides that code for an amino acid ○ there are 20 amino acids in our body ○ amino acid- monomer of protein ...
... ● Converts mRNA from transcription into protein (polypeptide) ● Codon- a sequence of 3 RNA nucleotides that code for an amino acid ○ there are 20 amino acids in our body ○ amino acid- monomer of protein ...
Green Fluorescent Protein (GFP)
... Plasmids & antibiotic resistance • Resistance is futile? – 1st recognized in 1950s in Japan – bacterial dysentery not responding to antibiotics – worldwide problem now • resistant genes are on plasmids that are swapped between bacteria ...
... Plasmids & antibiotic resistance • Resistance is futile? – 1st recognized in 1950s in Japan – bacterial dysentery not responding to antibiotics – worldwide problem now • resistant genes are on plasmids that are swapped between bacteria ...
BISC 6274 - GWU Biology Department
... Genes and Signals, by Mark Ptashne and Alexander Gann. Cold Spring Harbor Laboratory Press. 2002. You can download pictures from this book (as jpg or in pdf formats) at www.genesandsignals.org/gs.php. Another useful set of figures (again in jpg and pdf formats) are from Epigenetics and are available ...
... Genes and Signals, by Mark Ptashne and Alexander Gann. Cold Spring Harbor Laboratory Press. 2002. You can download pictures from this book (as jpg or in pdf formats) at www.genesandsignals.org/gs.php. Another useful set of figures (again in jpg and pdf formats) are from Epigenetics and are available ...
Chapter 12 Gene Mutation
... A mutation changes the nucleotide sequence of a gene. Germline mutations can be inherited, whereas a somatic mutation cannot. Many mutagens are chemicals or forms of radiation. The frequency of spontaneous mutations varies for different genes, but can be estimated from the observation of new dominan ...
... A mutation changes the nucleotide sequence of a gene. Germline mutations can be inherited, whereas a somatic mutation cannot. Many mutagens are chemicals or forms of radiation. The frequency of spontaneous mutations varies for different genes, but can be estimated from the observation of new dominan ...
File - The Tarrytown Meetings
... the steps of comparing and analyzing were merely thought processes. Myriad responded that the claims were analogous to those in Prometheus, in that the process necessarily included a transformation when the gene was sequenced. The ACLU responded that unlike Prometheus the claims only recited the men ...
... the steps of comparing and analyzing were merely thought processes. Myriad responded that the claims were analogous to those in Prometheus, in that the process necessarily included a transformation when the gene was sequenced. The ACLU responded that unlike Prometheus the claims only recited the men ...
Introduction to DNA
... Ethidium bromide (EtBr)…orange when mixed with DNA under UV light Methylene blue…dark blue…not as sensitive as EtBr viewed with white light ...
... Ethidium bromide (EtBr)…orange when mixed with DNA under UV light Methylene blue…dark blue…not as sensitive as EtBr viewed with white light ...
DOC - MIT
... b. After completing the above steps, it is likely that you will still have several candidate target sequences. You will decide which one is best by looking at the next highest matches in the BLAST search for each target sequence. i. Eliminate sequences that show a 20/20 or 19/19 identity with a gene ...
... b. After completing the above steps, it is likely that you will still have several candidate target sequences. You will decide which one is best by looking at the next highest matches in the BLAST search for each target sequence. i. Eliminate sequences that show a 20/20 or 19/19 identity with a gene ...
A spectrum of genes expressed during early stages of rice... flower development
... the rice and Arabidopsis genes, a probable function has been assigned on the basis of sequence similarity to previously studied genes from other systems. Apart from sequence similarity, function can be hypothesized from RNA and protein synthesis patterns and can be further tested through phenotypic ...
... the rice and Arabidopsis genes, a probable function has been assigned on the basis of sequence similarity to previously studied genes from other systems. Apart from sequence similarity, function can be hypothesized from RNA and protein synthesis patterns and can be further tested through phenotypic ...
File
... of genes simultaneously • to genotype multiple regions of a genome • Identify genes present in an organisms genome • Find out which genes are expressed within cells • Compare the genes present in two different organisms • To See which genes are being expressed in a specific cell at any given time • ...
... of genes simultaneously • to genotype multiple regions of a genome • Identify genes present in an organisms genome • Find out which genes are expressed within cells • Compare the genes present in two different organisms • To See which genes are being expressed in a specific cell at any given time • ...
AUGUSTUS: a web server for gene prediction in eukaryotes that
... The most reliable non-experimental method of annotation is considered to be the manual correction by experienced annotators of ab initio predictions in the presence of expressed sequence tag (EST) and protein alignments for the region under study. Recently, an automatic procedure has been developed ...
... The most reliable non-experimental method of annotation is considered to be the manual correction by experienced annotators of ab initio predictions in the presence of expressed sequence tag (EST) and protein alignments for the region under study. Recently, an automatic procedure has been developed ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.