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Slide 1
Slide 1

... back to genes. The expression of our genes is a contributing factor to aging. A person’s genetic makeup and gene expression profiles, combined with many other aging factors, including environmental exposure, determines the way he or she will age—both internally at the cell level and externally by sk ...
ageLOC Dermatic Effects Presentation
ageLOC Dermatic Effects Presentation

... back to genes. The expression of our genes is a contributing factor to aging. A person’s genetic makeup and gene expression profiles, combined with many other aging factors, including environmental exposure, determines the way he or she will age—both internally at the cell level and externally by sk ...
Human genetics of aging: the centenarians
Human genetics of aging: the centenarians

... “Mrs. Thaxton was the fourth-oldest person in the country and the sixth-oldest in the world, according to the California-based Gerontology Research Group. Mrs. Thaxton and her mother also hold the record as the world's oldest mother/daughter combination, with a combined age of 223 years.” “Mrs. Thax ...
CAPSTONE - Bioinformatics at School of Informatics
CAPSTONE - Bioinformatics at School of Informatics

... • Standard practice in comparative genomics ...
Presentation: Computation to Solve Problems
Presentation: Computation to Solve Problems

... A box is replaced by its value ...
Involvement of HLS1 in Sugar and Auxin
Involvement of HLS1 in Sugar and Auxin

... these mutants was named unusual sugar response2 (uns2). uns2 showed increased levels of amylase activity and anthocyanin accumulation in Suc-supplied leaf petiole as compared with the wild type (Fig. 1), implying a hypersensitivity to exogenous Suc in uns2. We further discovered that the left border ...
Drosophila lab recitation notes
Drosophila lab recitation notes

... If you want to investigate whether the distribution of F2 phenotypes that you observed in your results is different from the expected distribution if the genes were independently assorting? (or if the genes were linked), then you perform a chi-square (χ²) test. χ² tests can only be carried out on ac ...
TRANSPOSABLE GENETIC ELEMENTS
TRANSPOSABLE GENETIC ELEMENTS

... B. Transposable elements in eukaryotes are of two types: those that have DNA as their genetic material, and those that have RNA as their genetic material. 1. DNA transposable elements are exemplified by the P elements in Drosophila. a) P elements were discovered when it was found that certain strain ...
EXAM 3
EXAM 3

... True/False (1 point each) ...
Comparative Sequence Analysis of a Region on Human
Comparative Sequence Analysis of a Region on Human

... clones I5, A10, and 5D7 used to assemble the contiguous map of the designated mouse region are shown at the bottom. ...
Package ‘GenomicFeatures’ October 14, 2014
Package ‘GenomicFeatures’ October 14, 2014

- La Salle Elementary School
- La Salle Elementary School

... • Mendel found that two factors—one from a sperm cell and one from an egg cell—control each trait. • Dominant traits block the expression of recessive traits. Recessive traits are expressed only when two recessive factors are present. ...
Translation
Translation

... e, rRNA is coded by multiple genes in the genome the genes are tandomly arrayed, one after the other with a short spacer between (7 copies in E. coli, many copies in eukaryotes where they form the nucleolus). each rRNA gene is transcribed into one long pre-rRNA that contains all three subunits the l ...
Cluster Analysis in DNA Microarray Experiments
Cluster Analysis in DNA Microarray Experiments

... • Clustering strengthens the signal when averages are taken within clusters of genes (Eisen et al., 1998). • Clustering can be helpful for identifying gene expression patterns in time or space. • Clustering is useful, perhaps essential, when seeking new subclasses of cell samples (tumors, etc). • Cl ...
Lesson 1
Lesson 1

... • Mendel found that two factors—one from a sperm cell and one from an egg cell—control each trait. • Dominant traits block the expression of recessive traits. Recessive traits are expressed only when two recessive factors are present. ...
A golden fish reveals pigmentation loss in Europeans Data Activity
A golden fish reveals pigmentation loss in Europeans Data Activity

... Genetic origin of golden mutant zebrafish DNA or RNA sequences can be changed in many different ways. Some common types of mutations are single base pair changes (for example from A to T or C to G), insertions of additional nucleotides, or deletions (removal) of existing nucleotides. Parts of a gene ...
Genetic Mapping in Drosophila melanogaster
Genetic Mapping in Drosophila melanogaster

... this time, most of the larval body is replaced by the growth of specialized cells located on the ventral surface of the organism. These cells, located in regions called imaginal disks, develop into the structures of the adult fruit fly. About a day before the pupae are ready to hatch, the pupal case ...
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility

... Figure 1. The IKBKE SNV rs12142086 affects the binding of SF1 with DNA. (a) The SNV rs12142086 is predicted to be located in the binding motif of SF1. Introns are represented by grey horizontal lines and exons by vertical bars with numbers. The position of rs12142086 is highlighted with a star. In t ...
Expression of floral identity genes in Clianthus
Expression of floral identity genes in Clianthus

... August. Flower primordia were initiated within the inflorescence shortly thereafter (Fig. 2B). Although sepals could occasionally be distinguished between November and March, no further organogenesis was observed in flower primordia from inflorescences harvested before mid-April (Fig. 2C). Organogen ...
Fine scale mapping
Fine scale mapping

... Fully penetrant recessive disorder, incidence ~1/2500 live births in white populations, less common in other populations. Preliminary linkage analysis suggested 1.8Mb candidate region for a single CF gene on chromosome 7q31. More recently, a 3bp deletion, ΔF508, has been identified in the CFTR gene ...
Brief Introduction of Single Nucleotide Polymorphism: Basic Concept
Brief Introduction of Single Nucleotide Polymorphism: Basic Concept

... chemistries to label these probes have made it possible to use up to six spectrally distinguishable probes per reaction well. With the remarkable advances made in the characterization of human genome diversity, it has been possible to describe empirical patterns of SNPs and haplotype variation in th ...
Supplementary Discussion References
Supplementary Discussion References

... The differentially expressed gene list was obtained by meeting criteria: 1) intersection of both bipolar disorder and schizophrenia for significant genes, 2) passed ANCOVAs for restricted pH > 6.57 and 3) gene passed unrestricted ANCOVA for all pH. The list of genes that were found to be significant ...
Rabbit anti-WNT3 Rabbit anti-WNT3
Rabbit anti-WNT3 Rabbit anti-WNT3

... This polyclonal antibody is supplied as a 400 µL aliquot at a concentration of 0.25 mg/mL in phosphate buffered saline (pH 7.4) containing 0.1% sodium azide. This antibody is epitope-affinity purified from rabbit antiserum. ...
Functional and nonfunctional mutations distinguished by random
Functional and nonfunctional mutations distinguished by random

... and transferred into B. subtilis DB428-competent cells as described (6); 768 clones were picked with sterile toothpicks and grown in SG medium supplemented with 50 mgyml kanamycin at 37°C for 24 h in eight 96-well plates. The cells were spun down, and samples of the supernatants were examined in the ...
Synergies between assisted reproduction technologies and
Synergies between assisted reproduction technologies and

... when coupled to the FokI nuclease, create efficient geneediting tools [42–44]. The TALEN and CRISPR/Cas9 systems are easier to engineer and more reliable than the use of zinc finger nucleases [45]. In the presence of single- or double-stranded DNA homologous to the target sequence, these systems can ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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