The Old World monkey DAZ (Deleted in
... The cynDAZ cDNA sequence (Fig. 1) is a composite of the partial cDNA of the remaining fifth clone and a 5′-RACE product using adult monkey testis mRNA as a template. The 5′-RACE products overlapped the cDNA insert by 50 nucleotides and extended 471 nucleotides further to the 5′ end. The cynDAZ cDNA ...
... The cynDAZ cDNA sequence (Fig. 1) is a composite of the partial cDNA of the remaining fifth clone and a 5′-RACE product using adult monkey testis mRNA as a template. The 5′-RACE products overlapped the cDNA insert by 50 nucleotides and extended 471 nucleotides further to the 5′ end. The cynDAZ cDNA ...
Evolution of Genes and Genes in Evolution
... synthesis of the results of these two types of studies is probably not yet in the realm of what is achievable. However, it is not premature to survey the outlines of the situation which is emerging, and such surveys have been attempted from time to time, with varying degrees of success by many genet ...
... synthesis of the results of these two types of studies is probably not yet in the realm of what is achievable. However, it is not premature to survey the outlines of the situation which is emerging, and such surveys have been attempted from time to time, with varying degrees of success by many genet ...
Population Dynamics
... In Hoot Woods there are two kinds of mice: those with colored fur and those with albino (white) fur. These phenotypes have been recorded over several generations in a pedigree. The pedigree shows that two albino mice can have only albino offspring, and that two colored mice or one colored mouse and ...
... In Hoot Woods there are two kinds of mice: those with colored fur and those with albino (white) fur. These phenotypes have been recorded over several generations in a pedigree. The pedigree shows that two albino mice can have only albino offspring, and that two colored mice or one colored mouse and ...
Self-adaptation of Genome Size in Artificial Organisms | SpringerLink
... To close the gap with the environmental distribution, the organisms could then adapt the efficiency or the expression level of the genes they already own. Yet a finer tuning could be achieved by acquiring more and more balancing inhibitor/activator genes. However, Figure 3 shows that after a short phas ...
... To close the gap with the environmental distribution, the organisms could then adapt the efficiency or the expression level of the genes they already own. Yet a finer tuning could be achieved by acquiring more and more balancing inhibitor/activator genes. However, Figure 3 shows that after a short phas ...
We need an optimality criterion to choose a best estimate (tree
... How strongly is a phylogenetic hypothesis supported by the data? Bootstrap replicates generate new data sets by randomly sampling from the actual data, with replacement. These new data sets should contain phylogenetic signal similar to that in the original data. A high percentage of replicates (75%+ ...
... How strongly is a phylogenetic hypothesis supported by the data? Bootstrap replicates generate new data sets by randomly sampling from the actual data, with replacement. These new data sets should contain phylogenetic signal similar to that in the original data. A high percentage of replicates (75%+ ...
PART II
... at additional secondary sites. This occurred in the case of Roundup Ready® soya in which it was established that the additional DNA was not expressed and thus had no impact on the original safety assessment. Clearly such molecular characterisation of the GM crop is critical from the safety perspecti ...
... at additional secondary sites. This occurred in the case of Roundup Ready® soya in which it was established that the additional DNA was not expressed and thus had no impact on the original safety assessment. Clearly such molecular characterisation of the GM crop is critical from the safety perspecti ...
l Saccharomyces cerevisiae as a Genetic Model Organism
... or others depending on the genotype of the strain and its ability to utilize various carbon sources. Glucose is the richest and most readily available carbon source and a rich medium containing glucose is referred to as YEPD or YPD. Because of the abundant nutrient supply, cells divide rapidly on a ...
... or others depending on the genotype of the strain and its ability to utilize various carbon sources. Glucose is the richest and most readily available carbon source and a rich medium containing glucose is referred to as YEPD or YPD. Because of the abundant nutrient supply, cells divide rapidly on a ...
Stamm revision
... 2.3 Synthetic genetic interactions Availability of deletions in non-essential genes and conditional mutants in essential genes has allowed investigation of genetic interactions between the core splicing machinery. Synthetic enhancement/lethality occurs when one gene mutation exacerbates the severity ...
... 2.3 Synthetic genetic interactions Availability of deletions in non-essential genes and conditional mutants in essential genes has allowed investigation of genetic interactions between the core splicing machinery. Synthetic enhancement/lethality occurs when one gene mutation exacerbates the severity ...
overview-omics - SRI International
... Set from Any to All One way to think about drug targeting, e.g. Quick note – cross-species comparison from pathways Go to this from individual pathway pages Compares presence of pathway in question, and reactions of that pathway ...
... Set from Any to All One way to think about drug targeting, e.g. Quick note – cross-species comparison from pathways Go to this from individual pathway pages Compares presence of pathway in question, and reactions of that pathway ...
Genetics and genomics of behavioral and psychiatric disorders
... a simple mendelian trait, but rather displays patterns consistent with a complex trait. For such disease traits, multiple genetic and environmental factors may influence the susceptibility to the development of a phenotype [2]. Furthermore, a psychiatric disease phenotype may represent a final commo ...
... a simple mendelian trait, but rather displays patterns consistent with a complex trait. For such disease traits, multiple genetic and environmental factors may influence the susceptibility to the development of a phenotype [2]. Furthermore, a psychiatric disease phenotype may represent a final commo ...
Bioinformatics - University of Colorado Denver
... development of Celebrex, which is marketed as an arthritis therapy. Celebrex is a potent and specific inhibitor of COX-2. Celebrex is considered specific because it doesn’t inhibit COX-1, which is involved in synthesizing prostaglandins that aid in digestion. This is a remarkable accomplishment give ...
... development of Celebrex, which is marketed as an arthritis therapy. Celebrex is a potent and specific inhibitor of COX-2. Celebrex is considered specific because it doesn’t inhibit COX-1, which is involved in synthesizing prostaglandins that aid in digestion. This is a remarkable accomplishment give ...
An acyltransferase-like gene obtained by differential gene
... PCR-select subtraction analysis was conducted between cDNAs from the leaves of the bitter cultivar and sweet cultivar. From the first screening, 288 clones each were selected as specific candidates for the bitter and sweet cultivars. Using dot-blot hybridization, these clones were further delimited ...
... PCR-select subtraction analysis was conducted between cDNAs from the leaves of the bitter cultivar and sweet cultivar. From the first screening, 288 clones each were selected as specific candidates for the bitter and sweet cultivars. Using dot-blot hybridization, these clones were further delimited ...
Analysis of TALE superclass homeobox genes
... HAC (2). However, this analysis was incomplete and this group of genes has now been identified as the Meis genes (13,23,24). An unfinished cosmid sequence (T28F12, Genome Sequencing Center, personal communication) matching ceh-25 was found in the C.elegans genome project. Analysis of the ceh-25 regi ...
... HAC (2). However, this analysis was incomplete and this group of genes has now been identified as the Meis genes (13,23,24). An unfinished cosmid sequence (T28F12, Genome Sequencing Center, personal communication) matching ceh-25 was found in the C.elegans genome project. Analysis of the ceh-25 regi ...
demystifying-genomics
... a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the 100,000 or so genes of organisms such as plants, animals or humans.But the use of D ...
... a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the 100,000 or so genes of organisms such as plants, animals or humans.But the use of D ...
CHAPTER 15 Gene Mapping in Eukaryotes
... b. For either X-linked case, it is possible to cross the females with males of any type. As long as only male progeny are analyzed, the father’s X will be irrelevant. c. Phenotypes obtained in any of these crosses will depend on whether the alleles are arranged in coupling (cis) or repulsion (trans) ...
... b. For either X-linked case, it is possible to cross the females with males of any type. As long as only male progeny are analyzed, the father’s X will be irrelevant. c. Phenotypes obtained in any of these crosses will depend on whether the alleles are arranged in coupling (cis) or repulsion (trans) ...
The arbuscular mycorrhizal fungal protein glomalin is
... Hsp 60 gene from G. intraradices A cDNA fragment whose translation displayed high identity (66–73%) to the Hsp 60 genes previously identified from other fungi (Fig. 2) was identified from a G. intraradices cDNA library. Using CLUSTAL X (Thompson et al., 1997), an unrooted phylogenetic tree was const ...
... Hsp 60 gene from G. intraradices A cDNA fragment whose translation displayed high identity (66–73%) to the Hsp 60 genes previously identified from other fungi (Fig. 2) was identified from a G. intraradices cDNA library. Using CLUSTAL X (Thompson et al., 1997), an unrooted phylogenetic tree was const ...
Subfunctionalization: How often does it occur? How long does it take?
... chicken, Xenopus, and zebrafish by Van de Peer et al. (2001) who found an increase in evolutionary rate in about half of the duplicated genes. The third explanation introduced by Force et al. (1999) is that complementary degenerative mutations in the two copies lead to preservation of the duplicate c ...
... chicken, Xenopus, and zebrafish by Van de Peer et al. (2001) who found an increase in evolutionary rate in about half of the duplicated genes. The third explanation introduced by Force et al. (1999) is that complementary degenerative mutations in the two copies lead to preservation of the duplicate c ...
Demystifying genomics - Medical Research Council
... a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the 100,000 or so genes of organisms such as plants, animals or humans.But the use of D ...
... a single microarray in order to show, for instance,which are active during infections. That information could be useful in designing new antibiotics or other treatments. Current microarrays cannot accommodate all the 100,000 or so genes of organisms such as plants, animals or humans.But the use of D ...
Revised Parikh Ch 11
... Genes are passed from parents to offspring. (Mendel called genes, “factors.”) • Dominance- if two alleles in a gene pair are different, the dominant allele will control the trait and the recessive allele will be hidden • Segregation - each adult has two copies of each gene-one from each parent. Thes ...
... Genes are passed from parents to offspring. (Mendel called genes, “factors.”) • Dominance- if two alleles in a gene pair are different, the dominant allele will control the trait and the recessive allele will be hidden • Segregation - each adult has two copies of each gene-one from each parent. Thes ...
Expressed Sequence Tag (EST)
... - They represent a big part of the mammalian genome - They are found in a number of genomes (plants, …) - They induce errors in clustering and assembling - They should be MASKED, not deleted, to avoid false sequence assembling (also interesting for evolutionary studies. SSRs important for mapping of ...
... - They represent a big part of the mammalian genome - They are found in a number of genomes (plants, …) - They induce errors in clustering and assembling - They should be MASKED, not deleted, to avoid false sequence assembling (also interesting for evolutionary studies. SSRs important for mapping of ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.