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Is it Good to Share? The Parallel between Information
Is it Good to Share? The Parallel between Information

... What if the donor tells you a meme chosen randomly from those you don’t know? What if the donor tells you the highest fitness memes they know first? Do individuals actually know the fitness of their memes? If you learn a negative fitness meme, can you ignore it? Maybe fitness should depend only on t ...
The role of the SRY gene in determing sex.
The role of the SRY gene in determing sex.

... The patients DNA and control samples were tested by PCR(Polymerase chain reaction)amplification in figure A. Figure B shows fluorescent microscopy on the patients DNA. Fluorescence in situ hybridsation of patients DNA showed a green fluorescence on the short arm of the X chromosome. This gen was tra ...
SNP presentation
SNP presentation

... - women with certain BRCA1 SNPs have up to 85% risk of developing breast cancer ...
Document
Document

... Bioinformatics tools for Comparative Genomics of Vectors ...
14 Phylogenomic Approach to the Evolutionary Dynamics of Gene
14 Phylogenomic Approach to the Evolutionary Dynamics of Gene

... diverge to produce novel functions in a process known as neofunctionalization (Zhang, 2003). For example, some duplicated members of the RNaseA gene superfamily in primates evolved a novel antibacterial function that was not present in the common ancestral gene or its descendants (Zhang et al., 1998 ...
InterMine: extensive web services for modern
InterMine: extensive web services for modern

... with many new features planned, including more powerful search functions and data visualization. The web services InterMine’s web services make use of standard HTTP 1.0 method calls (often termed a RESTful web service) between client and server and thus the HTTP request methods GET and POST can be u ...
RNAi in Plants: An Argonaute-Centered View
RNAi in Plants: An Argonaute-Centered View

... proteins (Wu et al., 2009), following the 59 nucleotide-directed loading rule. However, regardless of the identities of their 59 nucleotides, DCL3-dependent lmiRNAs are recruited by AGO4 clade proteins. The specificity of sRNA sorting between AGO1 and AGO4 clade proteins is unlikely to be determined ...
RNA Editing, ADAR1, and the Innate Immune Response
RNA Editing, ADAR1, and the Innate Immune Response

... known that A-to-I editing occurs to a much greater extent in human cells than in mice due to the high content of the repeat sequences in the human genome [68], such as the Alu element, which only exists in primates. Therefore, the pathogenesis of diseases caused by errors in RNA editing might be mor ...
Deciphering the developmental program in the ascidian
Deciphering the developmental program in the ascidian

... peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. ...
Find the gene
Find the gene

... Study the entry How many basepairs (bp) long is the nucleotide sequence displayed? 626bp At what nucleotide position is the start codon located? That is the position where the coding sequence of the mRNA (CDS) begins. 51 Where does the coding sequence end? 494 How many nucletoides long is the coding ...
Brennan - Journal of Experimental Biology
Brennan - Journal of Experimental Biology

... mechanisms are contributing to the maintenance of the genetic break, such as compromised fertilization or embryonic development, which are currently under investigation. Our results are consistent with extended physiological plasticity at hypo-osmotic extremes in populations that have invaded freshw ...
A Gibberellin-Regulated Calcineurin B in Rice Localizes to
A Gibberellin-Regulated Calcineurin B in Rice Localizes to

... seedling tissues. Four full-length cDNAs (OsCBL1–4) and a partial sequence (OsCBL7) were cloned by reverse transcription-PCR or PCR from genomic DNA. Partial sequences (OsCBL1, 3, and 7) or full-length cDNA sequences (OsCBL2 and 4) were used as genespecific probes on northern blots since none crossh ...
Giant DNA Lab Manual.
Giant DNA Lab Manual.

... will be much easier to keep your DNA strands lined up. This lab must be your own work. Your lab report will be worth 20 points and must consist of answers to the following questions: Make up a protein that is 5 amino acids long. You will then design a gene from the hypothetical organism used in this ...
Leukaemia Section Lymphomatoid papulosis (LyP) with 6p25.3 rearrangement Atlas of Genetics and Cytogenetics
Leukaemia Section Lymphomatoid papulosis (LyP) with 6p25.3 rearrangement Atlas of Genetics and Cytogenetics

... (A) with characteristic pagetoid reticulosis-like epidermal involvement (B) at medium power. Inset in (A) shows high power image of atypical cells with small to medium nuclei and with the presence of frequent apoptotic bodies and mitotic figures. Immunohistochemical stains reveal a CD3 and CD30 posi ...
The Ins and Outs of Pedigree Analysis, Genetic
The Ins and Outs of Pedigree Analysis, Genetic

... that established breeds are separate entities among themselves, they all are genetically the same species. While a mating within a breed may be considered outbred, it still must be viewed as part of the whole genetic picture: a mating within an isolated, closely related, interbred population. Each b ...
Ontologies
Ontologies

... Answer: 155 phenotype genes are associated with the term “seed” 2e) With the answer from 2d, report how many phenotype genes in total are associated to the children terms of seed (GRO:0005339). Also explain why this number is not the same as you see next to the term seed (GRO:0005339). Hint: There a ...
Genome-wide transcription profiling of aerobic and anaerobic
Genome-wide transcription profiling of aerobic and anaerobic

... RNA extraction and sequencing Total RNA was extracted (Epicentre, Madison, WI) from two biological replicates of about 1010 planktonic cells and from the slides supporting 35 ± 5 μm3 μm−2 aerobic biofilm and 2.7 ± 0.3 μm3 μm−2 anaerobic biofilm. High-throughput sequencing of the mRNA was carried out ...
Glossary of Genetic Terms 11Jul15
Glossary of Genetic Terms 11Jul15

... allele. (2) One of the variant forms of a gene at a particular locus, or location on a chromosome. Different alleles produce variation in inherited characteristics such as hair color or blood type. In an individual one form of the allele (the dominant one) may be expressed more than another form (th ...
Editorial Novel Computing Technologies for Bioinformatics and
Editorial Novel Computing Technologies for Bioinformatics and

... identifying differential gene expressions between conditions, for discovering the major factors that cause diseases. Previous studies have not identified the correlations of differential gene expression between conditions; crucial but abnormal regulations that cause diseases might have been disregar ...
Bioinformatics Variant Analysis
Bioinformatics Variant Analysis

... sequence variation occurring when a single nucleotide - A, T, C, or G - in the genome differs between members of a species (or between paired chromosomes in an individual). Each individual has many single nucleotide polymorphisms that together create a unique DNA pattern for that individual. Typical ...
Leukaemia Section Follicular lymphoma (FL) Atlas of Genetics and Cytogenetics
Leukaemia Section Follicular lymphoma (FL) Atlas of Genetics and Cytogenetics

... No fusion protein. The t(14;18) brings about the juxtaposition of BCL-2 with the Ig heavy chain joining segment, with consequent marked overexpression of the BCL2 protein product. The majority of breakpoints on 18q22 fall into two regions: the major breakpoint region (60-70% of the cases) and the mi ...
Biogerontology: The Next Step
Biogerontology: The Next Step

... arrest by increasing the intracellular damage resulting in the upregulation of the socalled senescence-specific genes described above.52 Although such an experimental approach can facilitate the understanding of the regulation and interactions of various cell cycle-checkpoint genes, this approach ha ...
Database resources of the National Center for Biotechnology
Database resources of the National Center for Biotechnology

... organisms for which there are 70 000 or more ESTs in GenBank and now includes ESTs from 16 animals and 13 plants. Each UniGene cluster contains sequences that represent a unique gene, and is linked to related information, such as the tissue types in which the gene is expressed, model organism protei ...
Biomarkers in Gastrointestinal Cancer and Target Therapy
Biomarkers in Gastrointestinal Cancer and Target Therapy

... prevalence of HER2-positivity (range 8-34%) than distal diffuse gastric carcinomas . • The rate of HER2-positivity in esophageal adenocarcinoma is also variable, with one metaanalysis showing approximately 25% of esophageal adenocarcinomas over-expressing HER2. ...
Stop-Gain Mutations in PKP2 Are Associated with a Later
Stop-Gain Mutations in PKP2 Are Associated with a Later

... death. Pathogenic mutations in several genes encoding mainly desmosomal proteins have been reported. Our aim is to perform genotype-phenotype correlations to establish the diagnostic value of genetics and to assess the role of mutation type in age-related penetrance in ARVC. Methods and Results: Thi ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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