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Differences in DNA methylation patterns between humans and
Differences in DNA methylation patterns between humans and

... the ratio of the intensities of these two oligonucleotides differed significantly between human and chimpanzee in at least one tissue. By contrast, zero to three differences would be expected due to random experimental and biological variation, as is shown by permutating the species labels for each ...
Codon usage in the Mycobacterium tuberculosis corn
Codon usage in the Mycobacterium tuberculosis corn

... GenBank accession no. X58406) is 33 codons shorter than that of M . leprae. This appears to be due to a frameshift near the 3' end : insertion of an additional G into a run of three Gs at codons 341-342 restores a reading frame with a termination codon at a homologous position to that of M . leprae ...
Trackster+Circster
Trackster+Circster

... It is easy to change the order of the tracks on Trackster. If you want to place the third track (‘refgenedm3.gff3’) at the first position, click on the beginning of the dataset name and drag it to the desired position. The selected dataset will be indicated in blue. ...
Whole Genome Annotations Experimental data involving thousands
Whole Genome Annotations Experimental data involving thousands

...  The process of evolution has produced DNA ...
One amino acid makes the difference: the formation of ent
One amino acid makes the difference: the formation of ent

... functions in primary metabolism as essential plant growth hormones and are known to function in secondary metabolism as, for example, phytoalexins. The biosynthesis of labdane-related diterpenes is mediated by the action of class II and class I diterpene synthases. Although terpene synthases have be ...
v2 PEBiosystems News 2 01/00
v2 PEBiosystems News 2 01/00

... AmpliTaq Gold, GeneAmp and TaqMan are registered trademarks of Roche Molecular System, Inc. ICAT is a trademark of the University of Washington, exclusively licensed to Applied Biosystems Group of Applera Corporation. Paracel is a registered trademark of Paracel Inc. The ABI PRISM 3100 and the 3100- ...
Overview of genome analysis Page 421
Overview of genome analysis Page 421

... Assemble contigs from various chromosomes, then sequence and assemble them. A contig is a set of overlapping clones or sequences from which a sequence can be obtained. The sequence may be draft or finished. A contig is thus a chromosome map showing the locations of those regions of a chromosome wher ...
Conservation of gene function in behaviour
Conservation of gene function in behaviour

... cycles, have been well-described in diverse organisms. Additionally, as mentioned previously, the behavioural outputs of the clock (e.g. activity, sleep/wake cycles) are relatively easily compared between divergent species (figure 2). First, we provide some background on the biological clock in Dros ...
Hereditary Myopathy with Lactic Acidosis
Hereditary Myopathy with Lactic Acidosis

... Recombination is a process in which genetic material is exchanged between the maternal and the paternal chromosomes to ensure correct segregation and genetic diversification with each new offspring. The likelihood of recombination between two loci, for example a genetic marker (usually microsatellit ...
Evolution on the X chromosome: unusual patterns and processes
Evolution on the X chromosome: unusual patterns and processes

... autosomes, resulting in lower levels of neutral divergence at X- and W-chromosome loci. In Drosophila species, on the other hand, no such effect has been detected, as expected from the similar number of cell divisions estimated for male and female gametogenesis. ...
Facilitation of chromatin dynamics by SARs Craig M Hart and Ulrich
Facilitation of chromatin dynamics by SARs Craig M Hart and Ulrich

... reporter gene increased expression levels 24-fold in tobacco plant cell lines [22]. The SAR effect is only observed following stable integration into the genome in all biological systems tested [22–24]. These cis-acting elements hence appear to require a chromatin environment as transiently transfec ...
especially b-lymphocytes from patients with sjögren´s syndrome
especially b-lymphocytes from patients with sjögren´s syndrome

... Some components of the proteasome system has been shown to be dysregulated in total peripheral blood mononuclear cells (PBMCs) from patients with primary Sjögren's syndrome (pSS), but it is not yet clear which specific blood cell subsets are involved. Due to the central role of the proteasome for th ...
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))
Gene Section JUN (V-Jun sarcoma virus 17 oncogene homolog (avian))

... apoptosis and transformation. JUN promotes cell cycle transition from G1 phase to S phase by up-regulating cyclin D1 expression and antagonizing the function of p53and p21. The JUN protein is involved in both the induction and prevention of apoptosis, possibly dependent on the types and development ...
Understanding the Genetics of HHT
Understanding the Genetics of HHT

... What is the chance a dominant genetic disorder, like HHT, will get passed on to children? Since individuals with HHT actually have two copies of the “HHT gene”—one normal and one abnormal— each of their children has a 50% (1/2) chance of having HHT. This is because each egg and sperm has only one c ...
Test Information Sheet
Test Information Sheet

... Technical Limitations: Neither sequencing nor exon‐level aCGH can reliably detect mosaicism, and cannot detect  chromosomal aberrations. Deletions involving more than 20bp and insertions involving more than 10bp are not  reliably detected by the sequencing methodology, and deletions or duplications  ...
iGenetics: A Molecular Approach, 3e (Russell/Bose)
iGenetics: A Molecular Approach, 3e (Russell/Bose)

... Comparison of the genomes of different dog breeds may therefore shed light on which genetic elements are responsible for the radically different developmental pathways of different dog breeds–a process that may represent a microcosm of species-level differentiation over evolutionary time. Skill: Con ...
(RYR1) in a malignant hyperthermia Italian family
(RYR1) in a malignant hyperthermia Italian family

... segregation of the G6488- > C transversion in the family was confirmed by the ARMS technique (Figure 1, C and D): all the DNA samples that showed an aberrant SSCP pattern were amplified with the mutated primer (F39 mut) (Figure 1, D). The pedigree was also typed with polymorphic microsatellite marke ...
8.1 Human Chromosomes and Genes
8.1 Human Chromosomes and Genes

... The remaining pair of human chromosomes consists of the sex chromosomes, X and Y. Females have two X chromosomes, and males have one X and one Y chromosome. In females, one of the X chromosomes in each cell is inactivated and known as a Barr body. This ensures that females, like males, have only one ...
Occurrence of two types of Mn-superoxide dismutase in the green
Occurrence of two types of Mn-superoxide dismutase in the green

... Spirogyra, the degenerate primers we used, which were able to amplify both chloroplastic and cytosolic CuZnSOD cDNAs from land plants including moss and fern, resulted in amplification of chloroplastic but no cytosolic CuZn-SOD cDNA. These results suggest that Spirogyra may be devoid of the cytosoli ...
Document
Document

...  First, unless the marker locus and NF1 are so close together as to produce linkage disequilibrium between alleles at these loci, we would expect them to be in linkage equilibrium.  Second, new mutations represent a substantial fraction of all the alleles in an autosomal dominant disease with redu ...
Carotene genes from cassava-pchavarriaga.pdf
Carotene genes from cassava-pchavarriaga.pdf

... The tissue-specific carotene accumulation could be a result of upstream promoter regulation ...
The Effect of Chromosomal Position on the Expression of the
The Effect of Chromosomal Position on the Expression of the

... indicated that transposons introduced into germ-line chromosomes by transformation did not undergo detectable rearrangement (Spradling and Rubin, 1982; Rubin and Spradling, 1982). Southern blot analysis of five arbitrarily selected lines also failed to detect evidence of sequence alterations during ...
- Genetics
- Genetics

... undergo SA mutations, and so this species is well suited for testing the SA hypothesis, unlike species whose PARs include very few genes. Here, we analyze sequence diversity in a set of alleles from PAR genes. Our goals were twofold. The first is to further test for partial sex linkage, using populat ...
The Inheritance of Coat Colour in the Cardigan Welsh Corgi by Ken
The Inheritance of Coat Colour in the Cardigan Welsh Corgi by Ken

Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).
Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).

... of the above PCR products were first cloned into PCR II vector (Invitrogen) as described by the manufacturer, and clone R1 was sequenced directly from the PCR II vector using vector primers supplied by the manufacturer (Invitrogen). The full-length chicken cDNA product was subcloned into pBluescript ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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