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02 DNA and RNA and protein synthesis
02 DNA and RNA and protein synthesis

... together by two types of bonds.  Phosphodiester bonds link the phosphate group of one nucleotide to the sugar of an adjacent nucleotide along the side of the double helix.  The nitrogenous bases are held together by hydrogen bonds across a rung. ...
Linked Genes - Deepwater.org
Linked Genes - Deepwater.org

... That’s right, it’s never simple. There’s crossing over to consider. Remember this happens during meiosis I (during Prophase/Prometaphase I). In Drosophila, crossing over occurs about 18% of the time. What do you believe is the greatest factor in that potential for crossing over? Draw a chromosome to ...
Gene Expression Networks
Gene Expression Networks

... 1 Gene regulation at the single cell level Gene regulation is an intricate complex process, which involves genes, mRNAs and proteins that dictate cellular phenotypes and their response to external stimuli. Recent approaches employing genomics and proteomics and interactomic studies have helped probe ...
No Slide Title
No Slide Title

... Junctional diversity in splicing these regions together - imprecise joining with random insertion of nucleotides Somatic mutation within V region genes Finally, combinations of pairing of H chain isotypes and L-chain subtypes (kappa and lambda) ...
ANSWERS TO REVIEW QUESTIONS
ANSWERS TO REVIEW QUESTIONS

... 13. Markers may be variable restriction sites, variable short repeated sequences, or single nucleotide polymorphisms (SNPs). 14. Linkage: inherited together as on the same chromosome. Marker: a gene or DNA sequence with a known location that can be used to localize a gene of interest with an unknown ...
Gene!
Gene!

... • Intraspecific&gene&order&and&number& generally&relatively&stable&& ...
What is Bioinformatics?
What is Bioinformatics?

... proteins and EST sequences (Expressed Sequence Tags; mRNA sequences). • Gene prediction through similarity with proteins or ESTs in other organisms. • Gene prediction through comparison with other genomes; conserved regions are probably coding or regulatory regions. ...
The Hidden Genetic Program of Complex Organisms
The Hidden Genetic Program of Complex Organisms

... plexed with proteins. Within cells, small chemical tags (such as methyl and acetyl groups) can attach to segments of the DNA and to the chromatin proteins and thereby determine whether the genes in the associated DNA will be accessible for transcription or will stay silent. Recent results indicate t ...
Post-doc researcher - Labex GR-Ex
Post-doc researcher - Labex GR-Ex

... and 10 platforms: Genomics & Next generation sequencing, Cell imaging, Small animal imaging, Flow cytometry & cell sorting, Histology & Laser microdissection, Proteomics, Homologous recombination Full-time position founded by the Canceropole Ile-de-France for 2 years available in the Department Deve ...
Evolution of Populations
Evolution of Populations

... • A polygenic trait is controlled by two or more genes • Each gene of a polygenic trait may have more than one allele • Polygenic traits form many phenotypes • Variation in a polygenic trait in a population often forms a bell-shaped curve with most members near the ...
Unit 6 - John Adams Academy
Unit 6 - John Adams Academy

... As tRNA moves the amino acids together, long chains are formed (proteins) There are 20 different amino acids The structure and function of the protein depends upon the amino acids present and the order in which they are attached The base pairs (A, U, C, G) are arranged in codons or words of 3 Each c ...
31_operons
31_operons

... • Repressors and Activators are proteins that bind to DNA and control transcription. • Co-repressors and Inducers: small “effector” molecules that bind to repressors or activators ...
amino acids
amino acids

... RNA is produced one nucleotide at a time by matching base pairs with the nucleotides in DNA. ...
Information Flow in Eukaryotes (PowerPoint) Madison 2008
Information Flow in Eukaryotes (PowerPoint) Madison 2008

... By allowing a range of correct answers for tidbit 1, we accommodated both linear and non-linear approaches to solving the problem. Tidbit 1 also engaged kinesthetic and visual learners. We used grapes rather than wine (alcohol) as an example. We used an example from the plant/agricultural field beca ...
Extended Materials and Methods
Extended Materials and Methods

... RT-PCR and qPCR detection of messenger and small RNAs Preparation of the cDNA libraries from the total RNAs isolated from multiple tissues and sorted SMCs (pooled from 4 mice) obtained by FACS from smDicer-/-;Cre-GFP/+ or the WT control mice, as well as qPCR analysis on cDNAs, were performed as prev ...
Patterns in Development
Patterns in Development

... • Plants - root/shoot axis is determined first – not as many model organisms as much less resources are dedicated to plant research – positional information is more important than cell lineage (many cells are totipotent) – cell-signaling (induction) and transcription regulation drive development • ...
Bioinformatics and its applications
Bioinformatics and its applications

... - it can explore the causes of diseases at the molecular level - explain the phenomena of the diseases on the gene/pathway level - make use of computer techniques (data mining, machine learning etc), to analyze and interpret data faster - to enhance the accuracy of the results ...
The Origins of Life and Precambrian Evolution
The Origins of Life and Precambrian Evolution

... differences in the speed of self-replication or in chemical stability – In this case, the “genotype” is the chemical structure of the molecule, and the “phenotype” is the speed of selfreplication or stability of the molecule ...
Bio 262- Genetics Study Guide
Bio 262- Genetics Study Guide

... What does the study of genetics involve? What is the difference between “Classic Genetics” and “Modern Genetics” Define and briefly explain the four subdiscipline of genetics: Transmission genetics, molecular genetics, population genetics and quantitative genetics. What is the scientific method? Wha ...
Biology 12
Biology 12

... A polypeptide polymer is broken down in to smaller repeating subunits and water is required ...
Welkin`s Presentation on Assigning and Correctly
Welkin`s Presentation on Assigning and Correctly

... number. – Most of these will be supported by HHpred and BLAST on NCBI. ...
RNA Viruses
RNA Viruses

... site and share 3’ end of genome • May be produced by jumping polymerase - 7 base sequence in various parts of genome – Get recombinant viruses with mixed infections – DI particles are common ...
幻灯片 1 - TUST
幻灯片 1 - TUST

... c). Comparative genomics is third area of study, in which genomes from different organisms are compared to look for significant differences and similarities. This helps identify important, conserved portions of the genome and discern patterns in function and regulation. The data also provide much in ...
Beyond Dominant and Recessive Alleles
Beyond Dominant and Recessive Alleles

... 1. The inheritance of traits is determined by individual units known as genes. In organisms that reproduce sexually, genes are passed from parents to their offspring (children). 2. In cases in which two or more forms of the gene for a single trait exist, some forms of the gene may be dominant and ot ...
What is a GENE? - West East University
What is a GENE? - West East University

... genetically identical (they have exactly the same DNA in the same quantity). This process is known as mitosis. A cell may also divide in such a way as to allow sexual reproduction. In sexual reproduction, two members of the same species each make cells that have half the original amount of DNA (one ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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