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Genetic background affects susceptibility in nonfatal pneumococcal bronchopneumonia J.A. Preston , K.W. Beagley
Genetic background affects susceptibility in nonfatal pneumococcal bronchopneumonia J.A. Preston , K.W. Beagley

... and increased tumour necrosis factor (TNF)-a in bronchoalveolar lavage (BAL) fluid and lung tissue are important in pneumococcal clearance [17, 18]. There is increasing evidence that links the outcome of infectious disease to variations in the intensity of inflammatory responses that are determined ...
Intestinal epithelium in inflammatory bowel disease
Intestinal epithelium in inflammatory bowel disease

Function and Metabolism of Phospholipids in the Central and
Function and Metabolism of Phospholipids in the Central and

Snippets of information about ME/CFS
Snippets of information about ME/CFS

... with poor perfusion and pulsatilities, and increased hsCRP. According to Peter Behan, Professor of Neurological Sciences at the University of Glasgow, as these abnormalities have been shown to occur with such regularity, if they are present and if the clinical picture is right, then a firm diagnosis ...
Allergy and immunity to fungal infections and colonization
Allergy and immunity to fungal infections and colonization

... proposed for the diagnosis of ABPA (table 1) do not cause significant problems to the experienced clinician; however, they are not sufficient for reliable diagnosis of the syndrome. Moreover, independent of priority, not all of these criteria and symptoms must be fulfilled. Therefore, to improve dia ...
Immunotherapy for High-Risk and Metastatic Melanoma
Immunotherapy for High-Risk and Metastatic Melanoma

... – Predominantly CD-4+ (T-helper) lymphocytes ...
Sherwood 12
Sherwood 12

... • Lymphocytes respond only to antigens presented to them by antigen-presenting cells – Macrophages can be antigen-presenting cells • Cluster around appropriate β-cell clone • Phagocytosis occurs, processing the raw antigen intracellularly and presenting the processed antigen, exposing it to the oute ...
Investigating Nervous and Sensory Systems
Investigating Nervous and Sensory Systems

A beginners guide to SLE
A beginners guide to SLE

... autoimmune disease eg SLE • Genetic • Hormonal • Environmental • Stress ...
Stereotyped and specific gene expression programs in human innate immune responses to bacteria.
Stereotyped and specific gene expression programs in human innate immune responses to bacteria.

... I␬B␣) were also found within this cluster, reflecting the known autoregulation of this signaling pathway. Treatment with a combination of ionomycin and PMA can activate lymphocytes, as well as other leukocytes, by mimicking the intracellular signals that occur during natural responses to antigen. St ...
Dendritic cells in autoimmune diseases Burkhard
Dendritic cells in autoimmune diseases Burkhard

... they exist — are easily over-ruled and that autoimmunity can be induced when immunologically ignored autoantigens are presented in secondary lymphoid organs above a minimal concentration for a sufficient length of time. Therefore, it is conceivable that the default pathway of immune reactivity after ...
Thymus Gland - Spirit of Health
Thymus Gland - Spirit of Health

... The thymus gland The thymus gland is located in front of the heart and behind the sternum, or breastbone, and is part of the endocrine system. This gland is sometimes referred to as the center of youth and immunity. It produces white blood cells called T-Lymphocytes, or T-cells. The main function of ...
Differential fitness effects of immunocompetence and
Differential fitness effects of immunocompetence and

God-given Natural Healing Power Immune cells in your Body!
God-given Natural Healing Power Immune cells in your Body!

Feline Leukemia Virus (FeLV)- Specific IFNγ+ T
Feline Leukemia Virus (FeLV)- Specific IFNγ+ T

... cats, the majority will die from degenerative diseases while a minority will develop neoplastic and proliferative diseases.4 In general, viremic cats succumb to FeLV-related diseases within 2-4 years of infection. An improved understanding of the contribution of the different immune responses to the ...
Blood Bank - MATCOnline
Blood Bank - MATCOnline

... to the baby’s blood the last three weeks of pregnancy. So that this type of reaction doesn’t happen, a pharmaceutical named RhoGam is given to the mother. RhoGam contains Anti-D, so if the mother does get the baby’s blood with its D-antigens, the RhoGam antibodies will attach, making the baby D-anti ...
Effect of eliminating intermittent white blood cells
Effect of eliminating intermittent white blood cells

... the autoimmune diseases with unknown causes. The disease is treated currently by multiple immunosuppression, but side-effects are obvious after long time administration. Some immunosuppressants are too expensive to be used in patients with SLE; therefore, researchers are seeking new ways for the tre ...
Host parasite communications—Messages from
Host parasite communications—Messages from

Chlorella vulgaris restores bone marrow cellularity and cytokine
Chlorella vulgaris restores bone marrow cellularity and cytokine

... CV for 10 days, concomitant to a continuous offering of 1300 ppm lead acetate in drinking water, the treatment with the algae recovered the significantly reduced numbers of these cell populations to control values. As CV may have a myelostimulating effect through the induction of cytokines, we evalua ...
Chapter 13 The nervous system Expanding on neurons
Chapter 13 The nervous system Expanding on neurons

... The PNS: Autonomic division • Regulates the activity of involuntary muscles (cardiac and smooth) and glands • Divided into 2 divisions: – Sympathetic: coordinates the body for the “fight or flight” response by speeding up metabolism, heart rate and breathing while down regulating other functions – P ...
Nervous System - Dr. Eric Schwartz
Nervous System - Dr. Eric Schwartz

... Clinical Effects of Action Potential Inhibition • The generation of action potentials is prevented by local anesthetics such as procaine (Novocaine®) and lidocaine (Xylocaine®) because these drugs block voltage-gated Na+ channels. • Without action potentials, graded signals generated in the periphe ...
Toward An Understanding of Allergy and In
Toward An Understanding of Allergy and In

... other hand, provide cell-mediat• Lactase deficiency (dairy) ➔ bloating, flatulence, diarrhea, abdominal pain ed immunity. There is considerable interaction among components of the immune system. Subsets of Tcells, function as: helper T-cells, which stimulate B-cell activity; or as suppressor T-cells ...
Metabolic syndrome: the danger signal in atherosclerosis
Metabolic syndrome: the danger signal in atherosclerosis

... 2000). In the prospective Québec Cardiovascular Study, men with features of the metabolic syndrome had a 20-fold increase in their risk of CHD compared with men without such abnormalities, suggesting that these metabolic perturbations could act synergistically with classical risk factors (Lamarche e ...
Metabolic syndrome: the danger signal in
Metabolic syndrome: the danger signal in

... 2000). In the prospective Québec Cardiovascular Study, men with features of the metabolic syndrome had a 20-fold increase in their risk of CHD compared with men without such abnormalities, suggesting that these metabolic perturbations could act synergistically with classical risk factors (Lamarche e ...
Learning Objectives
Learning Objectives

... protoplasmic & fibrous Helps establish & maintain blood-brain barrier ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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