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Chapter 20-22 Lymphatic System
Chapter 20-22 Lymphatic System

... ex.) histamine (inc. capillary permeability & vasodilation), kinins (inc. capillary permeability, vasodilation, chemotaxin, stimulates complement system), prostaglandins (cause fever, enhance pain), leukotrienes (released by WBCs to coordinate tissue response) ...
Chapter 19: Disorders of the Immune System
Chapter 19: Disorders of the Immune System

... • subsequent Rh+ children are vulnerable ...
S1 File.
S1 File.

... monocytogenes expressing ovalbumin (L.m.-Ova, [7]) or the parental wild type Listeria monocytogenes strain 10403s (L.m.-wt). Brain Heart Infusion (BHI) medium was inoculated with listeria stock solution and incubated at 37°C until an OD600 of 0.05 - 0.1. After dilution with PBS to an appropriate con ...
Pathogens How Do They Cause Disease?
Pathogens How Do They Cause Disease?

... the cell to burst, releasing more virus to the ...
Ecological Developmental Biology: Integrating Epigenetics, Medicine
Ecological Developmental Biology: Integrating Epigenetics, Medicine

PG2003 Lecutre 14 The Complement Cascade
PG2003 Lecutre 14 The Complement Cascade

... • To illustrate how the complement system components are generated by three main routes all of which rely on cascades of enzyme activation • To emphasise the “classical” activation route as a salient example of the concept that innate and adaptive immune responses are functionally linked ...
factor v leiden mutation
factor v leiden mutation

... many receptors on NK cells. Class II MHC molecules: HLA DR, DP, DQ Present on the surface of antigen-presenting cells as: Dendritic cells, macrophages- monocytes, B-cells, and tissue specific cells. Protect against extracellular pathogens. Major ligand for: TCR on CD-4+ T- helper cells. ...
Inadequate flow of oxygen into the respiratory system due to
Inadequate flow of oxygen into the respiratory system due to

... – There are different kinds: IgG, IgM, IgA, IgE, IgD ...
Nutrition
Nutrition

...  It is required for DNA synthesis  RNA transcription  cell division ...
January 26, 2016
January 26, 2016

... vaccine. These findings seem to fit well with the “inflammaging” hypothesis stating that low-grade, chronic inflammation is a significant risk factor associated with morbidity and mortality in the elderly. As the number of elderly individuals increases worldwide, the importance of effective preventi ...
Immuno Revision Notes
Immuno Revision Notes

... Most are X‐linked MutatIon in CD40 ligand gene on T cells Disrupted interacIon between T cell and B cell Results in: – Failure of class switching – Elevated IgM – Reduced IgG, IgA, IgE ...
Blood
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Chapter 14: Lymphatic System and Immunity Introduction The is
Chapter 14: Lymphatic System and Immunity Introduction The is

... antigen receptor, it becomes activated and stimulates _________________________________ to produce antibodies ____________________________ T cells continually monitor the body's cells, recognizing and eliminating tumor cells and virus-infected cells by release of proteins, cutting holes and by other ...
Module #
Module #

... The immune response responds at the site of the infection and at the lymph nodes away from the infection. We can understand the immune response by following the course of an infection.  Barriers: Most pathogens are kept outside of the body by protective mechanisms such as tears, stomach acid and ci ...
SpecificDefensessimple version
SpecificDefensessimple version

... GENERATING ANTIBODY DIVERSITY – 3 mechanisms 1) Genomic Rearrangement (during differentiation) 2) Insertions/Deletions when “pasted” together 3) Hypermutation – up to 10,000 times higher than normal ...
Kidney Transplant Rejection - URMC
Kidney Transplant Rejection - URMC

... time to recognize the foreign antigens and make an immune response to them. To prevent acute rejection, transplant patients are treated with immunosuppressive drugs. Immunosuppressive drugs block the immune system action by reducing the production of antibodies or T cells by white blood cells. The p ...
Bowel obstruction (Text)
Bowel obstruction (Text)

... plasma cells. The submucosa is the strongest layer of the bowel wall, which should be taken into account when performing sutured anastomoses. Networks of arterioles, lymphatic and venous plexuses, and nerves crisscross through the submucosa. Meissner’s submucosal neural plexus interconnects with ne ...
Immunology Hypersensitivity Autoimmune Disease Infectious
Immunology Hypersensitivity Autoimmune Disease Infectious

... • Frontline attackers during an immune response • Multi-lobed nuclei • Carrying tons of granules containing proteins such as cytokines and antimicrobial peptides ...
Microbiology: Basic Concepts of Immunology pg. 1 Haleigh Stidham
Microbiology: Basic Concepts of Immunology pg. 1 Haleigh Stidham

... cope with infections or trauma. It’s mostly due to the host’s response to the infection/pathogen. 2. Another important feature is the immunological status of your patient will dictate how you treat these patients a. i.e. radiation, chemotherapy, AIDS, genetic deficiencies—all have depressed immune s ...
Cellular mechanisms: host defence
Cellular mechanisms: host defence

... Activation of TLRs stimulates the generation and release of chemokines and other cytokines that act on vascular endothelial cells, attract other leukocytes to the area and give rise to systemic manifestations of the inflammatory response such as fever. ...
Ch 43-45 PPT
Ch 43-45 PPT

... 1) Nonspecific defense – unspecialized, general defense against all  Ex. Skin, cilia, gastric juices, mucus 2) 2nd line of nonspecific defense ...
BIOC39H – Immunology  Winter 2012 Course Syllabus
BIOC39H – Immunology Winter 2012 Course Syllabus

Systemic lupus erythematosus
Systemic lupus erythematosus

... Immune system dysfunction The disease is characterised by the production of ‘self’ (auto) antibodies (directed against nuclear ‘self’ (auto) antigens), inflammation and organ damage. The presence of antinuclear antibodies has been detected in the serum of a majority of patients before the onset of c ...
Inhibitors of Transitions & Biofilms Cause Yeast Cells to Lose Virulence ools
Inhibitors of Transitions & Biofilms Cause Yeast Cells to Lose Virulence ools

Natural Killer T Cells
Natural Killer T Cells

... addition to antibody formation, B cells also process and present protein antigens. T Lymphocytes: T lymphocytes are involved in the regulation of the immune response and in cell mediated immunity, and help B cells to produce antibody. Mature T cells express antigenspecific T cell receptors (TCR). De ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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