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Hypersensitivity Reactions
Hypersensitivity Reactions

... bring serum components, including IgG Abs, to the site of worm infestation. The IgG Abs bind to the surface of the worm and attracts the eosinophils, which have migrated to the area as a result of the chemotactic effects of ECF-A. The eosinophils then bind to the IgG-coated worm via their membrane r ...
AIDS vaccines
AIDS vaccines

... Traditional vaccines work mainly by priming the immune system so that it knows how to make antibodies to a particular infectious agent. Antibodies are proteins that stick onto a pathogen and gum up its works. The active principle of the vaccine, known as an antigen, is the bit of the pathogen that t ...
IMMUNE RESPONSE
IMMUNE RESPONSE

No T cells
No T cells

... an identical MHC gene locus T-cells recognize products of MHC genes as self or non-self If any cell of an individual starts to produce foreign (viral or bacterial) or abnormal (tumor associated) proteins, the T-cells recognize these antigen presenting cells as altered self cells and respond against ...
Ch. 14 Blood Notes
Ch. 14 Blood Notes

... • Biliverdin breaks down into bilirubin (orange) • The iron gets reused to make more hemoglobin or is stored in the liver as ferritin. ...
No T cells
No T cells

... an identical MHC gene locus T-cells recognize products of MHC genes as self or non-self If any cell of an individual starts to produce foreign (viral or bacterial) or abnormal (tumor associated) proteins, the T-cells recognize these antigen presenting cells as altered self cells and respond against ...
Microorganisms and Disease
Microorganisms and Disease

... • Gastric Juice: HCl, enzymes, mucus, acidic • Interferon: eukaryotic cells, surface receptors ...
STAPHYLOCOCCUS GRAM POSITIVE SPHERICAL BACTERIA
STAPHYLOCOCCUS GRAM POSITIVE SPHERICAL BACTERIA

... LEUKOCIDIN: TOXIN THAT ACTS ON PMN LEUCOCYTES , DESTROYING PHAGOCYTES. SUPERANTIGENS & IMMUNITY STIMULATE ‘T’ LYMPHOCYTES NON-SPECIFICALLY WITHOUT NORMAL ANTIGENIC RECOGNITION ...
Gene Section IL17F (interleukin 17F) Atlas of Genetics and Cytogenetics
Gene Section IL17F (interleukin 17F) Atlas of Genetics and Cytogenetics

PHA 321 - Biosciences II
PHA 321 - Biosciences II

... A) antibodies are modified, at the time of antigen exposure, to specifically react with the antigen. B) self-reactive T cells are killed in the thymus. C) B cells producing autoantibodies are eliminated in the thymus. D) each B cell is already programmed to produce a specific antibody. E) b and c 36 ...
Signaling Through Immune System Receptors
Signaling Through Immune System Receptors

NIH Public Access
NIH Public Access

... What are the distinguishing features of memory cells? First, memory implies that an antigenactivated cell or its clonal progeny can survive for a relatively long time after the pathogen or antigen has been cleared from the host. These cells must then be able to respond to re-exposure to the same ant ...
immune system support
immune system support

... *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. ...
blood
blood

... blood vessels (vasculature) and platelets play important role Primary Hemostatic plug temporarily arrests bleeding. Insoluble fibrin strands deposit on the initial plug to reinforce and stabilize.  The fibrin originates from soluble plasma proteins. ...
Immune System
Immune System

... antibodies (unable to prove antibody involvement). Antigen:Molecules capable of stimulating an immune response(AB or Lymphocyte). Heptan:small molecule bind to P.P to form macromolecule. Antibodies:immunoglobulins that can recognize and bind to a specific antigen.IgG,IgA,IgM,IgD+IgE Complement:20 di ...
Acknowledgements - Bourns College of Engineering
Acknowledgements - Bourns College of Engineering

... D. Levy and J. Darnell, Nat Rev Mol Cell Biol (2002) 3: 651-662 ...
021309.M1-Immuno.Cytokines - Open.Michigan
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... Chemokine receptors are usually named by the chemokine they bind. CXCR4 is a coreceptor, along with CD4, for HIV on T lymphocytes. CCR5 is a co-receptor for HIV on monocytes/macrophages. Individuals who are homozygous for a mutation in CCR5 do not progress to AIDS, even after an HIV infection. ...
cell - Castle High School
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... Innate immunity—nonspecific, used against many organisms: • Includes barriers, such as skin and molecules toxic to invaders, as first line of defense. • Second line of innate defenses includes phagocytic cells, which ingest foreign cells and other particles. • These defenses may be present all the t ...
Chapter 30 Microbial Interactions (미생물의 상호작용) 1
Chapter 30 Microbial Interactions (미생물의 상호작용) 1

... membranes of integuments (외피) and intestinal  linings – Degrade carbohydrate‐protein complexes  between cells – Disrupt host cell surface ...
European Respiratory Society Annual Congress 2012
European Respiratory Society Annual Congress 2012

Physiology Lecture 3
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... - Islet cell transplant. 2- Type II diabetes ● Usually occurs after age 40, and it is more common. ● Type II is caused by insufficient insulin or less responsive target cell receptors. ● Although type II is hereditary, its onset correlates with obesity and an inactive lifestyle. ● Type II diabetes c ...
Leukemia
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Reading Guide for Week 11_new
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Document
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... • Their disadvantage is that the foreign antibodies themselves elicit an immune response. • To avoid this, animal immunoglobulin can now be ‘ humanized ‘ by genetic engineering to combine the antigenbinding ( Fab ) site of a mouse monoclonal antibody with human immunoglobulin. ...
Eman Mohamed Ali Hassan_Pathogenesis2
Eman Mohamed Ali Hassan_Pathogenesis2

... Cytokines produced by mast cells stimulate the recruitment of leukocytes, which cause the late phase reaction. The principal leukocytes involved in this reaction are eosinophils, neutrophils, and Th2 cells. Mast cell-derived tumor necrosis factor (TNF) and IL-4 promote neutrophil- and eosinophil-ric ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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