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PANDAS - Oxford Academic - Oxford University Press
PANDAS - Oxford Academic - Oxford University Press

... factors. Post-streptococcal autoimmunity has been postulated as one possible mechanism for some. The acronym PANDAS (for paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) has been given to a subgroup of paediatric patients who meet five inclusionary criteria ...
The United Kingdom Primary Immune Deficiency (UKPID) Registry
The United Kingdom Primary Immune Deficiency (UKPID) Registry

... Since Bruton’s first description of agammaglobulinaemia as a PID in 1952 [1] there has been an explosion of knowledge in this area, with more than 200 gene defects contributing to even more distinct disease phenotypes [2,3]. The rarity of many forms of PID requires national and international collabo ...
Adult Bites
Adult Bites

... Adult Decision Support Tools: BITES ...
Enterobacteriaceae
Enterobacteriaceae

... If the gram-negative bacterium ferments lactose and/or sucrose, acid end products will be produced and cause the colonies and the phenol red in the agar around the colonies to turn yellow. If lactose and sucrose are not fermented but the amino acid lysine is decarboxylated, ammonia, an alkaline end ...
PDF
PDF

... Allergic dermatitis—acute ...................................... Irritant dermatitis—acute ........................................ Dermatitis and reactions affecting the skin—acute, n.e.c. ..................................................................... Other poisoning, toxic, noxious, or alle ...
Celiac Disease, Inflammation and Oxidative Damage: A
Celiac Disease, Inflammation and Oxidative Damage: A

... stress and induce the release of pro-inflammatory cytokines [8,9]. As a consequence, elimination of gluten from the diet (gluten free diet, GDF) results in a clinical improvement in CD patients. A previous celiac disease genome-wide association study (GWAS) demonstrated risk variants in the human le ...
Single-nucleotide polymorphisms of toll
Single-nucleotide polymorphisms of toll

... Toll-like receptors (TLRs) are a family of evolutionarily conserved proteins and play a key role in the innate immune system by directly recognizing pathogen-derived elements, including viral and bacterial DNA, lipopolysaccharides, and proteoglycans. The TLR ability to recognize microbial components ...
The gut microbiome in human immunodeficiency virus infection
The gut microbiome in human immunodeficiency virus infection

... is a reservoir of CD4+ T cells. In addition to being a major immune hub, the human gastrointestinal tract harbors trillions of commensal microorganisms, the microbiota, which have recently been shown to play critical roles in health. Alterations in the composition and function of microbiota have bee ...
Review articles Mucosal vaccination – an old but still vital strategy1
Review articles Mucosal vaccination – an old but still vital strategy1

... informed on 3rd October 2011 that a half of the Nobel Prize in Physiology or Medicine was given to Ralph M. Steinman „for his discovery of the dendritic cell and its role in adaptive immunity” [15]. In 1973 he identified a new cell type that he called the dendritic cell (déndron, being Greek for a t ...
The Philippine Ebola Preparedness Plan
The Philippine Ebola Preparedness Plan

... • Persons suspected to be suffering from Ebola should be taken to the nearest health unit immediately for medical attention • Severe cases require intensive supportive care • No vaccine is yet available for EVD but several vaccines are being tested and it could be several years before large quantiti ...
Antibiotic Susceptibility Pattern of Aerobic and Anaerobic Bacteria
Antibiotic Susceptibility Pattern of Aerobic and Anaerobic Bacteria

Classification of Infections in Intensive Care Units: A Comparison of
Classification of Infections in Intensive Care Units: A Comparison of

... acknowledged that incubation time represents an inaccurate criterion for classifying infections in the critically ill patients. According to the pathogenesis of ICU-acquired infections, acquisition of a PPM is followed by carriage and overgrowth of that micro-organism before colonization and infecti ...
Major Diagnostic Category (MDC) to MS
Major Diagnostic Category (MDC) to MS

... etiology and, in general, are associated with a particular medical specialty. MDC 1 to MDC 23 are grouped according to principal diagnoses. Patients are assigned to MDC 24 (Multiple Signif​icant Trauma) with at least two signif​icant trauma diagnosis codes (either as principal or second​aries) from ...
Is complement good, bad, or both? New functions of the complement
Is complement good, bad, or both? New functions of the complement

... in parallel experiments, similar observations have led to evidence of the impact of C3a and C5a complement components in the modulation of neuronal survival [2, 3]. The key role of these factors in nerve integrity preservation is reinforced by the fact that the specific receptors, C3aR and C5aR, can ...
Carbapenem-resistant or Multidrug
Carbapenem-resistant or Multidrug

... the therapeutic role of colistin. Colistin, also known as polymyxin E, exerts its antibacterial effect by disturbing the bacterial cell membrane, thus increasing permeability, and eventual cell death. Colistin has retained activity against many multiple drug resistant gram-negative pathogens includi ...
RHINOSINUSITIS
RHINOSINUSITIS

...  Bleeding or hemorrhagic secretion  Fetor  Altered or absent sense of smell  Paine in the head or in the face.  Disease of neighboring organs such as teeth, lacrimal apparatus, eyes, mouth, throat, and lungs. ...
The Immune System
The Immune System

... Copyright © 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins ...
Guideline for diagnosis and treatment of adult bronchiectasis
Guideline for diagnosis and treatment of adult bronchiectasis

... antibiotics may be required Combination antibiotics are recommended for infections due to strains of Pseudomonas aeruginosa that are resistant to one or more antipseudomonal antibiotics (including ciprofloxacin) or if the clinician suspects the patient will require many antibiotic courses, to reduce ...
Wheezy Child: Diagnostic and Therapeutic Approach
Wheezy Child: Diagnostic and Therapeutic Approach

... • 0-3 years, RSV (+) Lung function test < RSV(-) • Bronchodilatator response RSV (+) Lung fxn test > RSV (-) The difference persists during 11st year. ...
Differences in Participation of Innate and Adaptive Immunity to
Differences in Participation of Innate and Adaptive Immunity to

... inactivated virus [12], thus suggesting that the capacity to produce an innate immune response is present at birth. Recently, proliferative responses and interferon (IFN)–g expression were detected to RSV-infected, UV light–inactivated cells in onethird of infants exposed to an RSV season at the app ...
Lymphoma
Lymphoma

... Lateral branchiogenic cysts – Fistulas - First branchial cleft cysts account for less than 1 percent of branchial cleft anomalies. They typically appear on the face near the auricle. - Second branchial cleft cysts (most common type of branchial cleft anomaly). They are usually located just inferior ...
Evaluation of Combination Regimens in GT1
Evaluation of Combination Regimens in GT1

... • Among HIV/HCV coinfected participants, HCC incidence rose from 0.2 to 2.8 cases per 1000 person-years between 2000 and 2009, with the largest jump in 2008-2009. • Most patients with HCC (79%) died during follow-up, all but 2 due to complications related to liver cancer. • The median survival time ...
Major Diagnostic Category (MDC) to MS
Major Diagnostic Category (MDC) to MS

... etiology and, in general, are associated with a particular medical specialty. MDC 1 to MDC 23 are grouped according to principal diagnoses. Patients are assigned to MDC 24 (Multiple Signif​icant Trauma) with at least two signif​icant trauma diagnosis codes (either as principal or second​aries) from ...
The purpose of this summary is exclusively educational, to provide
The purpose of this summary is exclusively educational, to provide

... Mast cells and basophils: (i) originate from HSCs; (ii) can de novo synthesize and secrete >30 cytokines; (iii) can also preform and store cytokines (e.g. TNF, IL-4); (iv) mast cells, but not basophils, can synthesize PGD2; (v) cytokine spectrum appears to be more TH2-restricted for basophils; (vi) ...
Hazardous Biological agents
Hazardous Biological agents

... so assigned and, unless the context indicates otherwise“biological agent” means any micro-organism, cell culture or human endoparasite, including any which have been genetically modified, which may cause an infection, allergy or toxicity, or otherwise createa hazard to human health; ”decontamination ...
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Hygiene hypothesis

In medicine, the hygiene hypothesis is a hypothesis that states that a lack of early childhood exposure to infectious agents, symbiotic microorganisms (e.g. gut flora or probiotics), and parasites increases susceptibility to allergic diseases by suppressing the natural development of the immune system. In particular, the lack of exposure is thought to lead to defects in the establishment of immune tolerance.The hygiene hypothesis has also been called the ""biome depletion theory"" and the ""lost friends theory"".
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