![[2] Kee HJ*, Eom GH*, Joung H et al., Activation of histone](http://s1.studyres.com/store/data/005630680_1-ca26e8e660c76684aa082bdde0969dfb-300x300.png)
[2] Kee HJ*, Eom GH*, Joung H et al., Activation of histone
... diseases and histone deacetylase (HDAC) 2 phosphorylation and following its activation are closely associated with those of process [1, 2]. Recently, we have demonstrated that the acetylation of HDAC2 K75 could induce S394 phosphorylation [3]; however, specific mechanism for intermodifications regul ...
... diseases and histone deacetylase (HDAC) 2 phosphorylation and following its activation are closely associated with those of process [1, 2]. Recently, we have demonstrated that the acetylation of HDAC2 K75 could induce S394 phosphorylation [3]; however, specific mechanism for intermodifications regul ...
Symposium Program
... stages of megakaryopoiesis. Without these interactions, multiple bloodrelated diseases result. GATA-DNA: The C-terminal zinc finger of GATA-1 interacts with ‘GATA’ sequence on the minor groove of the DNA. An additional factor, FOG-1 is needed to allow transcription by binding the N-terminal zinc fin ...
... stages of megakaryopoiesis. Without these interactions, multiple bloodrelated diseases result. GATA-DNA: The C-terminal zinc finger of GATA-1 interacts with ‘GATA’ sequence on the minor groove of the DNA. An additional factor, FOG-1 is needed to allow transcription by binding the N-terminal zinc fin ...
Nuclear Factor-90 of Activated T-Cells: A Double
... DNA-binding activity and transcriptional activation to the immunosuppressant drugs cyclosporin A and FK506 (31, 32). Both subunits of the heterodimeric complex have been cloned and found to consist of subunits of Mr ) 45 000 (NF45) and Mr ) 90 000 (NF90). The phosphorylation state of this ARRE-2 bin ...
... DNA-binding activity and transcriptional activation to the immunosuppressant drugs cyclosporin A and FK506 (31, 32). Both subunits of the heterodimeric complex have been cloned and found to consist of subunits of Mr ) 45 000 (NF45) and Mr ) 90 000 (NF90). The phosphorylation state of this ARRE-2 bin ...
New NMR experimental techniques: Protein structural compactness
... NMR spectroscopy is a unique technique to study conformational dynamics over a widerange of time scales, from picoseconds to hours. Real-Time NMR provides information of transient populated states based on the acquisition of NMR experiments with fastpulsing methods. On the other hand relaxation-disp ...
... NMR spectroscopy is a unique technique to study conformational dynamics over a widerange of time scales, from picoseconds to hours. Real-Time NMR provides information of transient populated states based on the acquisition of NMR experiments with fastpulsing methods. On the other hand relaxation-disp ...
PowerPoint 프레젠테이션
... potential. The actual conformational change corresponding to eversion of binding site could be quite small. ...
... potential. The actual conformational change corresponding to eversion of binding site could be quite small. ...
Gene Section MERTK (c-mer proto-oncogene tyrosine kinase) Atlas of Genetics and Cytogenetics
... et al., 2006). Specifically, Gas6 has been shown to bind TAM receptors in the immunologlobulin domains (Sasaki et al., 2006). The intracellular component of the MERTK receptor includes the tyrosine kinase domain (aa 600-848). Within this tyrosine kinase domain is a signature motif, KWIAIES, which is ...
... et al., 2006). Specifically, Gas6 has been shown to bind TAM receptors in the immunologlobulin domains (Sasaki et al., 2006). The intracellular component of the MERTK receptor includes the tyrosine kinase domain (aa 600-848). Within this tyrosine kinase domain is a signature motif, KWIAIES, which is ...
Hybrid enzymes Pierre Béguin
... they are easy to manipulate, and fusion of proteins with specific tagging domains has now become a standard tool for protein engineers. Vectors encoding signal peptides have long been developed to allow secretion in various heterologous hosts, and many are featured in catalogs of manufacturers of mo ...
... they are easy to manipulate, and fusion of proteins with specific tagging domains has now become a standard tool for protein engineers. Vectors encoding signal peptides have long been developed to allow secretion in various heterologous hosts, and many are featured in catalogs of manufacturers of mo ...
A: Ca 2+
... Ca2+ channels Ca2+ influx from extracellular milieu (e.g. -adrenergic receptor occupancy in muscle cells Ca2+ influx rate and force of heart beat). 2. Increased intracellular [Ca2+] - Third messenger: Immediate vs. Sustained responses - Ca2+ binds to its ubiquitous intracellular recepto ...
... Ca2+ channels Ca2+ influx from extracellular milieu (e.g. -adrenergic receptor occupancy in muscle cells Ca2+ influx rate and force of heart beat). 2. Increased intracellular [Ca2+] - Third messenger: Immediate vs. Sustained responses - Ca2+ binds to its ubiquitous intracellular recepto ...
Document
... Ca2+ channels Ca2+ influx from extracellular milieu (e.g. -adrenergic receptor occupancy in muscle cells Ca2+ influx rate and force of heart beat). 2. Increased intracellular [Ca2+] - Third messenger: Immediate vs. Sustained responses - Ca2+ binds to its ubiquitous intracellular recepto ...
... Ca2+ channels Ca2+ influx from extracellular milieu (e.g. -adrenergic receptor occupancy in muscle cells Ca2+ influx rate and force of heart beat). 2. Increased intracellular [Ca2+] - Third messenger: Immediate vs. Sustained responses - Ca2+ binds to its ubiquitous intracellular recepto ...
Bioinformatics - Indiana University
... A more common, recessive form of inherited Parkinson's disease is linked to a mutation in the parkin gene. The loss of enzyme activity resulting from this mutation leads to an accumulation of protein substrates, including alpha-synuclein, in the cell. ...
... A more common, recessive form of inherited Parkinson's disease is linked to a mutation in the parkin gene. The loss of enzyme activity resulting from this mutation leads to an accumulation of protein substrates, including alpha-synuclein, in the cell. ...
INTRODUCTION TO MYCOLOGY
... This process began operating in 1975 and was the first commercial continuously operating process for the production of a filamentous fungus. The process was developed in Finland for the utilization of spent sulfite liquor, derived from food processing, that contains monosaccharides and acetic acid. ...
... This process began operating in 1975 and was the first commercial continuously operating process for the production of a filamentous fungus. The process was developed in Finland for the utilization of spent sulfite liquor, derived from food processing, that contains monosaccharides and acetic acid. ...
Phosphorylation of Single Stranded RNA Virus Proteins and
... DENV NS5 has been demonstrated to interact with NS3 in the cytoplasm of infected cells. This interaction between the two DENV NS proteins was dependent on NS5 phosphorylation [24]. NS3 is an interesting case because there is implication that flaviviral NS3 may be phosphorylated, particularly in the ...
... DENV NS5 has been demonstrated to interact with NS3 in the cytoplasm of infected cells. This interaction between the two DENV NS proteins was dependent on NS5 phosphorylation [24]. NS3 is an interesting case because there is implication that flaviviral NS3 may be phosphorylated, particularly in the ...
Cytoskeleton Handout
... Actin participates in force generation (eg., cell motility) via interactions with myosin. Myosin is an actin-activated ATPase that converts chemical energy (i.e., ATP) into mechanical energy by moving along microfilaments (or by moving the actin filaments). Cellular motility is a dynamic process inv ...
... Actin participates in force generation (eg., cell motility) via interactions with myosin. Myosin is an actin-activated ATPase that converts chemical energy (i.e., ATP) into mechanical energy by moving along microfilaments (or by moving the actin filaments). Cellular motility is a dynamic process inv ...
NUTRITION
... What are the two classes of vitamins and name the vitamins in each class List (a) 3 sources of vitamin A (b) 2 sources of carotene What is the functions of vitamin D? What happens if you are deficient in Vitamin B? List 4 functions for vitamin C ...
... What are the two classes of vitamins and name the vitamins in each class List (a) 3 sources of vitamin A (b) 2 sources of carotene What is the functions of vitamin D? What happens if you are deficient in Vitamin B? List 4 functions for vitamin C ...
Biochemical studies on antioxidant
... fragmentation, changes in absorption and fluorescence spectra and others. All these modifications can be used as markers of protein damage by free radicals. Aim of the Work: The aim of the present study was to investigate the antioxidant activities of the aqueous extracts of dry green of pods Phaseo ...
... fragmentation, changes in absorption and fluorescence spectra and others. All these modifications can be used as markers of protein damage by free radicals. Aim of the Work: The aim of the present study was to investigate the antioxidant activities of the aqueous extracts of dry green of pods Phaseo ...
Conserved BK Channel-Protein Interactions Reveal Signals
... no protein spots (Figure S1C–F), inferring that our immunoprecipitation assay had few if any false positive proteins. Our approach to identifying proteins with high confidence from their peptide matches was defined in two steps: 1) proteins identified by MS had a molecular weight variance of 65 kDa ...
... no protein spots (Figure S1C–F), inferring that our immunoprecipitation assay had few if any false positive proteins. Our approach to identifying proteins with high confidence from their peptide matches was defined in two steps: 1) proteins identified by MS had a molecular weight variance of 65 kDa ...
Cell-Based Applications of Living Colors® Proteins
... BD™ Pathway Confocal Bioimager. Panel A. HEK 293 clonal cell lines stably expressing AmCyan1, ZsGreen1, ZsYellow1, or HcRed1 were mixed and plated into the same well and then imaged at 20X magnification using the BD™ Pathway Bioimager. Chroma Technology filter sets were used to separate the signal o ...
... BD™ Pathway Confocal Bioimager. Panel A. HEK 293 clonal cell lines stably expressing AmCyan1, ZsGreen1, ZsYellow1, or HcRed1 were mixed and plated into the same well and then imaged at 20X magnification using the BD™ Pathway Bioimager. Chroma Technology filter sets were used to separate the signal o ...
University of Groningen Hyperthermia and protein
... process of cell killing by heat and of heat radiosensitization are unclear as yet. Data from the literature indicate an important role for heat-induced protein denaturation and aggregation in hyperthermic cell killing. It has already been shown that thermotolerance (transient resistance induced by a ...
... process of cell killing by heat and of heat radiosensitization are unclear as yet. Data from the literature indicate an important role for heat-induced protein denaturation and aggregation in hyperthermic cell killing. It has already been shown that thermotolerance (transient resistance induced by a ...
Coordinated Regulation of AIB1 Transcriptional Activity by
... Ultimately, the function of a protein is also regulated by additional mechanisms particularly post-translational modifications. It has been reported that the activity of the SRC proteins is regulated by phosphorylation. For example, SRC-1 has been shown to be phosphorylated by mitogen-activated prot ...
... Ultimately, the function of a protein is also regulated by additional mechanisms particularly post-translational modifications. It has been reported that the activity of the SRC proteins is regulated by phosphorylation. For example, SRC-1 has been shown to be phosphorylated by mitogen-activated prot ...
Structure, function and biosynthesis of GLUTI
... whereas the catalytic turnover was decreased by 7.5-fold. These data infer that G1nl6' forms part of the exofacial glucose-binding site and that the asparagine substitution alters the specificity of sugar binding at this site. In addition, the reduced catalytic turnover suggests that substitutions a ...
... whereas the catalytic turnover was decreased by 7.5-fold. These data infer that G1nl6' forms part of the exofacial glucose-binding site and that the asparagine substitution alters the specificity of sugar binding at this site. In addition, the reduced catalytic turnover suggests that substitutions a ...
File
... • Carrier proteins assist molecules across the cell membrane. This process is called carrier mediated transport. The makeup of the amino acid chains in the protein determines the size and shape of the carrier protein. This, in turn, determines what molecule can be received by the carrier protein to ...
... • Carrier proteins assist molecules across the cell membrane. This process is called carrier mediated transport. The makeup of the amino acid chains in the protein determines the size and shape of the carrier protein. This, in turn, determines what molecule can be received by the carrier protein to ...
Protein phosphorylation
Protein phosphorylation is a post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it to become activated, deactivated, or modifying its function. The reverse reaction of phosphorylation is called dephosphorylation, and is catalyzed by protein phosphatases. Protein kinases and phosphatases work independently and in a balance to regulate the function of proteins. The amino acids most commonly phosphorylated are serine, threonine, and tyrosine in eukaryotes, and histidine in prokaryotes, which play important and well-characterized roles in signaling pathways and metabolism. However, many other amino acids can also be phosphorylated, including arginine, lysine, and cysteine. Protein phosphorylation was first reported in 1906 by Phoebus Levene at the Rockefeller Institute for Medical Research with the discovery of phosphorylated vitellin. However, it was nearly 50 years until the enzymatic phosphorylation of proteins by protein kinases was discovered.