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Glyceraldehyde-3-Phosphate Dehydrogenase Is a GABAA Receptor
... the 33P-labeling of the ␣1 subunit increased, whereas that of P38 decreased (Fig. 1 A). Kinetic studies at 1 mM [Mg 2⫹] suggested that phosphorylation of P38 occurred before any significant incorporation of 33P-phosphate at the ␣1 subunit (data not shown). We made the assumption that P38 is the rece ...
... the 33P-labeling of the ␣1 subunit increased, whereas that of P38 decreased (Fig. 1 A). Kinetic studies at 1 mM [Mg 2⫹] suggested that phosphorylation of P38 occurred before any significant incorporation of 33P-phosphate at the ␣1 subunit (data not shown). We made the assumption that P38 is the rece ...
Lecture 1: Key Concepts in Stereoselective Synthesis
... molecule. Because of its efficiency (high TON and TOF) it is one of the most common asymmetric transformations used on industrial scale. These reactions often are highly chemo-, region- and enantioselective (depending on the substrate). Unfortunately screening of multiple reaction parameters need to ...
... molecule. Because of its efficiency (high TON and TOF) it is one of the most common asymmetric transformations used on industrial scale. These reactions often are highly chemo-, region- and enantioselective (depending on the substrate). Unfortunately screening of multiple reaction parameters need to ...
Computational Studies of Multi-Active Site Enzymes
... editing and, (ii) glutamine deamination by glucosamine-6-phosphate synthase (GlmS). MST1: MD and QM/MM-MD methods were used to examine (i) differences in the binding of its cognate and non-cognate Thr- and Ser-AMP substrates respectively, and (ii) mechanism of hydrolytic pre-transfer editing. In con ...
... editing and, (ii) glutamine deamination by glucosamine-6-phosphate synthase (GlmS). MST1: MD and QM/MM-MD methods were used to examine (i) differences in the binding of its cognate and non-cognate Thr- and Ser-AMP substrates respectively, and (ii) mechanism of hydrolytic pre-transfer editing. In con ...
Why gold nanoparticles are more precious than pretty
... state physicists and material scientists and are currently well understood. Materials on the 1–100 nm scale were not studied by either group in the past. It was just recently shown that on this size scale the properties of a material become dependent on its size and shape. However, the interface bet ...
... state physicists and material scientists and are currently well understood. Materials on the 1–100 nm scale were not studied by either group in the past. It was just recently shown that on this size scale the properties of a material become dependent on its size and shape. However, the interface bet ...
Flux limitations in the ortho pathway of benzoate
... The growth behaviour of AIcaIigenes eutrophus using various concentrations of benzoate was investigated. In batch culture, growth was exponential and growth rate (p) and yields ( Y ) were high [cc = 0.51 h-l and Y*nzoate = 056 mol carbon (mol carbon)-l] when low concentrations of benzoate (< 5 mM) w ...
... The growth behaviour of AIcaIigenes eutrophus using various concentrations of benzoate was investigated. In batch culture, growth was exponential and growth rate (p) and yields ( Y ) were high [cc = 0.51 h-l and Y*nzoate = 056 mol carbon (mol carbon)-l] when low concentrations of benzoate (< 5 mM) w ...
Chapter 4 Chemical Quantities and Aqueous Reactions
... the lesser component of the solution that changes state is called the solute the greater component that keeps its state is called the solvent if both components start in the same state, the major component ...
... the lesser component of the solution that changes state is called the solute the greater component that keeps its state is called the solvent if both components start in the same state, the major component ...
MCAD - MSOE Center for BioMolecular Modeling
... Intermolecular Interactions Modeled in MCAD, FAD and ETF MCAD Active Site: Glu376, Glu199, Leu103, Ser142, Met249, Asp253, Arg388 Folding of MCAD: 2 Dimers Combine: Arg28:A and Glu86:D Tetramer: Lys304, Glu300, Gln342, Asp346, Arg383 ...
... Intermolecular Interactions Modeled in MCAD, FAD and ETF MCAD Active Site: Glu376, Glu199, Leu103, Ser142, Met249, Asp253, Arg388 Folding of MCAD: 2 Dimers Combine: Arg28:A and Glu86:D Tetramer: Lys304, Glu300, Gln342, Asp346, Arg383 ...
The Chemistry and Evolution of Enzyme Function
... Remarkably, about 30% of the EC numbers bearing more than one reaction are linked to different types of reactions, bearing key differences in catalysed bond changes. Several recommendations to improve the description of complex biochemical reaction data in the EC classification were proposed. This d ...
... Remarkably, about 30% of the EC numbers bearing more than one reaction are linked to different types of reactions, bearing key differences in catalysed bond changes. Several recommendations to improve the description of complex biochemical reaction data in the EC classification were proposed. This d ...
Problem 1-2 - IPN-Kiel
... To determine the iron(III) content in a solution it is precipitated with ammonia, filtered through ashfree filters, washed with water and at the end with ammonium nitrate solution. The filter with the precipitate is given into a porcelain crucible and heated with a Bunsen burner, at first slowly and ...
... To determine the iron(III) content in a solution it is precipitated with ammonia, filtered through ashfree filters, washed with water and at the end with ammonium nitrate solution. The filter with the precipitate is given into a porcelain crucible and heated with a Bunsen burner, at first slowly and ...
Stoichiometry
... c. Identify the limiting reagent if 3 moles of ammonia is combined with 5 moles of oxygen divide each mole by the molar coefficient and look for smaller value (3 mol NH3)/4 = 0.75 vs. (5 mol O2)/7 = 0.71 ⇒ O2 is the LR d. Identify the limiting reagent if 10. g of ammonia is combined with 28 g of oxy ...
... c. Identify the limiting reagent if 3 moles of ammonia is combined with 5 moles of oxygen divide each mole by the molar coefficient and look for smaller value (3 mol NH3)/4 = 0.75 vs. (5 mol O2)/7 = 0.71 ⇒ O2 is the LR d. Identify the limiting reagent if 10. g of ammonia is combined with 28 g of oxy ...
GCSE Chemistry Sample Assessment Materials
... Sulfur is present as an impurity in coal and forms sulfur dioxide gas when it burns S + O2 → SO2 Sulfur dioxide enters the atmosphere and reacts with / dissolves in rainwater Produces significantly acidic solution / sulfuric acid which falls as acid rain Acid rain erodes limestone statues ...
... Sulfur is present as an impurity in coal and forms sulfur dioxide gas when it burns S + O2 → SO2 Sulfur dioxide enters the atmosphere and reacts with / dissolves in rainwater Produces significantly acidic solution / sulfuric acid which falls as acid rain Acid rain erodes limestone statues ...
Lactate and Lactic Acid
... important function of the liver while exercising, and lactate is the most important precursor for the process of guconeogenesis 3, 7. While the hydrogen (H+) resulting from glycolysis can lower pH, increasing acidity, much of the H+ is buffered, converted to CO2 and simply exhaled. If the accumulati ...
... important function of the liver while exercising, and lactate is the most important precursor for the process of guconeogenesis 3, 7. While the hydrogen (H+) resulting from glycolysis can lower pH, increasing acidity, much of the H+ is buffered, converted to CO2 and simply exhaled. If the accumulati ...
Nature template
... I. How much CO2 can be incorporated into seed protein ? We considered the possibility that the reduced CO2 emission in light was due to its re-fixation via phosphoenolpyruvate carboxylase or pyruvate carboxylase. The product, oxaloacetate, could be converted into amino acids and stored in proteins o ...
... I. How much CO2 can be incorporated into seed protein ? We considered the possibility that the reduced CO2 emission in light was due to its re-fixation via phosphoenolpyruvate carboxylase or pyruvate carboxylase. The product, oxaloacetate, could be converted into amino acids and stored in proteins o ...
File
... Calculate moles of oxygen needed to react with 0.128 mol of ammonia: 5 mol O2 nW = 0.128 mol NH3 × = 0.160 mol 4 mol NH3 Since the required amount of oxygen is more than the amopunt available to react, oxygen is limiting and ammonia is in excess. The problem can also be solved by calculating moles o ...
... Calculate moles of oxygen needed to react with 0.128 mol of ammonia: 5 mol O2 nW = 0.128 mol NH3 × = 0.160 mol 4 mol NH3 Since the required amount of oxygen is more than the amopunt available to react, oxygen is limiting and ammonia is in excess. The problem can also be solved by calculating moles o ...
Examination 2: Chapters 8 through 11
... The MEOS will oxidize more alcohol than the alcohol dehydrogenase enzyme The alcohol dehydrogenase enzyme will oxidize more alcohol than the MEOS system The MEOS will reduce more alcohol than the alcohol dehydrogenase enzyme The alcohol dehydrogenase enzyme will reduce more alcohol than the MEOS sys ...
... The MEOS will oxidize more alcohol than the alcohol dehydrogenase enzyme The alcohol dehydrogenase enzyme will oxidize more alcohol than the MEOS system The MEOS will reduce more alcohol than the alcohol dehydrogenase enzyme The alcohol dehydrogenase enzyme will reduce more alcohol than the MEOS sys ...
Carbon and electron flow in Clostridium butyricum
... be accomplished by stimulating H, production. Surprisingly, the reducing power is not used to form H,, but rather a more reduced compound, 1,3-PD. The concentrations of the fermentation end-products have been extensively studied in C. but_yriczlm(Biebl, 1991; Biebl e t al. , 1992 ; Gunzel, 1991 ; Gu ...
... be accomplished by stimulating H, production. Surprisingly, the reducing power is not used to form H,, but rather a more reduced compound, 1,3-PD. The concentrations of the fermentation end-products have been extensively studied in C. but_yriczlm(Biebl, 1991; Biebl e t al. , 1992 ; Gunzel, 1991 ; Gu ...
Metabolism of Plasma Membrane Lipids in
... plasma membrane of mycobacteria and corynebacteria in more detail. Lipids are categorized into the following four classes based on their key structural features. ...
... plasma membrane of mycobacteria and corynebacteria in more detail. Lipids are categorized into the following four classes based on their key structural features. ...
Electron Transport Chains of Lactic Acid Bacteria
... proton motive force (PMF). This is in contrast to fermentation, defined as the oxidation of organic compounds using endogenous electron acceptors that are usually catabolic intermediates of the same organic compounds. LAB as a group are generally considered non-respiring and obligate fermentors. Fer ...
... proton motive force (PMF). This is in contrast to fermentation, defined as the oxidation of organic compounds using endogenous electron acceptors that are usually catabolic intermediates of the same organic compounds. LAB as a group are generally considered non-respiring and obligate fermentors. Fer ...
the effect of ozone on photosynthesis and respiration of
... The amounts of the major constituents of the air, nitrogen and oxygen, are fairly constant and account for 99%ofthe atmosphere near the earth's surface. In clean air, the remaining one percent is made up of carbon dioxide, water vapor and a variety of other compounds. The minor gaseous constituents ...
... The amounts of the major constituents of the air, nitrogen and oxygen, are fairly constant and account for 99%ofthe atmosphere near the earth's surface. In clean air, the remaining one percent is made up of carbon dioxide, water vapor and a variety of other compounds. The minor gaseous constituents ...
Active Site of Ribonuclease A - Department of Biochemistry | UW
... positions 12 and 119 of RNase A (Jackson et al. 1994). The pH-rate profile of this variant retains its bell shape, but shifts to lower pH. Because the pKa of 4fluorohistidine is lower than that of histidine, this perturbation is consistent with both 4-fluorohistidine residues participating in cataly ...
... positions 12 and 119 of RNase A (Jackson et al. 1994). The pH-rate profile of this variant retains its bell shape, but shifts to lower pH. Because the pKa of 4fluorohistidine is lower than that of histidine, this perturbation is consistent with both 4-fluorohistidine residues participating in cataly ...
Archive Microbiology
... of the pyruvate synthesis both in Anacystis nidulans and Azotobacter vinelandii (Table 2). The significance of this finding is not yet clear in the moment. In all other organisms tested, no significant activity was found for either the exchange or the synthesis reaction. The pyruvate dehydrogenase c ...
... of the pyruvate synthesis both in Anacystis nidulans and Azotobacter vinelandii (Table 2). The significance of this finding is not yet clear in the moment. In all other organisms tested, no significant activity was found for either the exchange or the synthesis reaction. The pyruvate dehydrogenase c ...
Bioactivation of Selenocysteine Se-Conjugates by a Highly Purified
... and yielded a highly purified enzyme that was 1000-fold enriched according to its increased specific activity with S-(1,2-dichlorovinyl)L-cysteine (1,2-DCV-Cys) as a substrate. Matrix-assisted laser desorption time-of-flight (MALDI-TOF) mass spectrometry analysis of this protein revealed a single MH ...
... and yielded a highly purified enzyme that was 1000-fold enriched according to its increased specific activity with S-(1,2-dichlorovinyl)L-cysteine (1,2-DCV-Cys) as a substrate. Matrix-assisted laser desorption time-of-flight (MALDI-TOF) mass spectrometry analysis of this protein revealed a single MH ...
2. Lect. Urea cycle
... BENEFIT OF GIVING NEOMYCIN TO HEPATO COMROMISED PATIENT Oral administration of NEOMYCIN reduces the number of intestinal bacteria responsible for this NH3 production. ...
... BENEFIT OF GIVING NEOMYCIN TO HEPATO COMROMISED PATIENT Oral administration of NEOMYCIN reduces the number of intestinal bacteria responsible for this NH3 production. ...
cell biology - Bio
... The overall theme for the book is the cell as the unit of life. We begin (Chapters 1–3) by describing the components of the cell as seen under the microscope. We then (Chapters 4–8) turn to the central dogma of molecular biology and describe how DNA is used to make RNA which in turn is used to make ...
... The overall theme for the book is the cell as the unit of life. We begin (Chapters 1–3) by describing the components of the cell as seen under the microscope. We then (Chapters 4–8) turn to the central dogma of molecular biology and describe how DNA is used to make RNA which in turn is used to make ...
GIBBERELLIN BIOSYNTHESIS: Enzymes, Genes and Their
... The last review of GA biosynthesis in this series, by Graebe (38), was followed by several reviews covering this topic (68, 75, 121). Graebe’s article focused on GA-biosynthetic pathways in cell-free systems, characteristics of biosynthetic enzymes, and factors affecting GA production. He predicted ...
... The last review of GA biosynthesis in this series, by Graebe (38), was followed by several reviews covering this topic (68, 75, 121). Graebe’s article focused on GA-biosynthetic pathways in cell-free systems, characteristics of biosynthetic enzymes, and factors affecting GA production. He predicted ...
Evolution of metal ions in biological systems
Evolution of Metal Ions in Biological Systems refers to the incorporation of metallic ions into living organisms and how it has changed over time. Metal ions have been associated with biological systems for billions of years, but only in the last century have scientists began to truly appreciate the scale of their influence. Major (iron, manganese, magnesium and zinc) and minor (copper, cobalt, nickel, molybdenum, tungsten) metal ions have symbiotically aligned with living organisms and the associated complexes have evolved over time.