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The Process of Cellular Respiration
The Process of Cellular Respiration

... Why do biologists pay so much attention to glucose? It’s because most other food molecules are broken down to release energy in much the same way. Proteins are broken down into individual amino acids, which are converted to compounds that can enter either glycolysis or the Krebs cycle. Carbohydrates ...
Chapter 1 Non-Canonical Amino Acids in Protein Engineering
Chapter 1 Non-Canonical Amino Acids in Protein Engineering

... under conditions where the non-canonical amino acid is targeted (though surely not exclusively) to the protein of interest. The metabolic pathways for amino acid synthesis in E. coli are thoroughly understood, and amino acid auxotrophs are readily available and easy to generate. Strains containing t ...
Oxidation and Reduction
Oxidation and Reduction

... Neutral atoms/molecules ...
Southern Blot
Southern Blot

... 5. Consider the following two human genes, each with two possible alleles. The PIP gene, coding for prolactin-inducible protein, is known to be on the short arm of chromosome 7. The location of the KEL gene, which codes for a specific red blood cell antigen, is unknown. Consider the pedigree shown ...
Document
Document

... and B, held together by two disulfide bonds. •A chain: 21 residues •B chain: 30 residues ...
Nuclear Magnetic Resonance (NMR) Spectroscopy
Nuclear Magnetic Resonance (NMR) Spectroscopy

Topic guide 5.4: Chemical behaviour of organic compounds
Topic guide 5.4: Chemical behaviour of organic compounds

... of organic compounds Organic molecules, based on chains and rings of carbon atoms, make up the vast majority of the compounds in existence. All have their origins in chemicals in living systems; some are found naturally in these systems while others are synthesised by chemists from materials derived ...
Blood Glucose Concentration
Blood Glucose Concentration

... • Acts to damp rise in glucose following digestion/absorption • Main effect is to increase glucose uptake by all cells ...
The Relationship between Chemiosmotic Parameters
The Relationship between Chemiosmotic Parameters

... condition for the following treatment being that only the fully protonated form is significantly membrane-permeable. The concentrations of the anionic form in the two phases are related by a consideration of the Henderson-Hasselbalch equation in each phase and equating the internal and external conc ...
Fatty Acid Metabolism
Fatty Acid Metabolism

... What is one important difference between plants and animals with respect to fatty acid metabolism? ...
Ch_9 - Bartlett High School
Ch_9 - Bartlett High School

... Figure 9.16 ATP yield per molecule of glucose at each stage of cellular respiration ...
Dialene 4—Fat Loss You Can FEEL!
Dialene 4—Fat Loss You Can FEEL!

... When the albumin-FFA complex reaches muscle tissue, the FFAs are released and are transported into a muscle cell. Once in the muscle cell, the FFAs can reesterfy (rebind) with glycerol to form triglycerides or bind with intramuscular proteins to be used for energy production in the mitochondria. In ...
Slides 3 - Department of Computer and Information Science and
Slides 3 - Department of Computer and Information Science and

... • O and N are generally more likely than C to hbond to water – hydrophilic • We group the amino acids into three general groups: – Hydrophobic – Charged (positive/basic & negative/acidic) – Polar ...
Biosynthesis of Nucleotides 2 - University of Alabama at Birmingham
Biosynthesis of Nucleotides 2 - University of Alabama at Birmingham

... salvaged and recycled to form nucleotides via phosphoribosyltransferase reactions • In humans, however, pyrimidines are recycled from nucleosides, but free pyrimidine bases are not salvaged • Catabolism of cytosine and uracil yields alanine, ammonium ion, and CO2 • Catabolism of thymine yields -am ...
CAP5510 - Bioinformatics - UF CISE
CAP5510 - Bioinformatics - UF CISE

... • O and N are generally more likely than C to hbond to water – hydrophilic • We group the amino acids into three general groups: – Hydrophobic – Charged (positive/basic & negative/acidic) – Polar ...
7.014 Section Problem:
7.014 Section Problem:

... c) How could you design a similar enzyme to cleave after aspartic acid? d) Speculate on the effect of changing the aspartic acid in protease B to a glutamic acid. e) There are three amino acids required for the active site to function and three amino acids involved in substrate recognition – why th ...
Griffith`s Experiment
Griffith`s Experiment

... 1. RNA polymerase binds to DNA in the nucleus and separates the DNA strand for 1 gene. 2. RNA polymerase “reads” 1 strand of DNA to produce a strand of messenger RNA (mRNA). 3. Complementary RNA nucleotides pair across from the DNA nucleotides (A-U; G-C, C-G; T-A) 4. RNA polymerase links the nucleot ...
Nitrogen lectures (Part 2)
Nitrogen lectures (Part 2)

... • DNA composed of chains on nucleotides composed of: – Deoxyribose – Phosphoric acid – 1 of 4 purine or pyrimidine bases: » Adenine » Cytosine » Guanine » Thymine • Three nucleotides represent the codon for one amino acid in a protein chain • Messenger RNA is produced from DNA – If DNA has mRNA will ...
Chapter 5 Macromolecules
Chapter 5 Macromolecules

... surgical thread that decomposes after the wound or incision heals. ...
Pyruvate dehydrogenase complex
Pyruvate dehydrogenase complex

... Hans Krebs showed that the oxidation of acetate is accomplished by a cycle TCA cycle, Citric Acid Cycle or Krebs Cycle • Pyruvate from glycolysis is oxidatively decarboxylated to acetate and then degraded to CO2 in TCA cycle • Some ATP is produced • More NADH and FADH2 are made • NADH goes on to ma ...
Glycogen Metabolism and Gluconeogenesis
Glycogen Metabolism and Gluconeogenesis

... • Fructose-2,6-bisphosphate allosterically activates the glycolysis enzyme Phosphofructokinase-1, promoting the relaxed state, even at relatively high [ATP]. Activity in the presence of fructose2,6-bisphosphate is similar to that observed when [ATP] is low. Thus control by fructose-2,6-bisphosphate, ...
Fatty Acid Synthesis
Fatty Acid Synthesis

... Formation of a double bond in a fatty acid involves the following endoplasmic reticulum membrane proteins in mammalian cells:  NADH-cyt b5 Reductase, a flavoprotein with FAD as prosthetic group.  Cytochrome b5, which may be a separate protein or a domain at one end of the desaturase.  Desaturase, ...
Organic Chemistry
Organic Chemistry

... • Each peptide bond is planar and has the s-trans conformation. • The C=O and N-H groups of peptide bonds from adjacent chains point toward each other and are in the same plane so that hydrogen bonding is possible between them. • All R- groups on any one chain alternate, first above, then below the ...
Chemistry
Chemistry

Chapter 25 Chapter Topics Fatty Acid Biosynthesis
Chapter 25 Chapter Topics Fatty Acid Biosynthesis

... • Different “Families” according to distance of last double bond from methyl end: • ω-9 (oleic acid, 9-C18:1) • ω-7 (palmitic acid, 9-C16:1) • ω-6 (linoleic acid, 9,12-C18:2)—only from plants. • Arachidonic acid made from dietary linoleic acid ...
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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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