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Supplementary Figures (doc 928K)
Supplementary Figures (doc 928K)

... entities). Stacked percentage distribution of level 0 cluster sizes from the group of all sequences, divided by cluster specificity. The “specificity” of a cluster is determined by the number of sequences that belong to the CLL group or the non-CLL group. If all sequences are non-CLL then the cluste ...
Brooker Chapter 8
Brooker Chapter 8

... Duplications tend to be less detrimental ...
Genetic Contribution to Coronary Atherosclerosis
Genetic Contribution to Coronary Atherosclerosis

... Understanding the genetic mechanisms underlying coronary artery disease is as complex as it is important. Despite current advances in molecular genetics, genomics and bioinformatics, deciphering the genetic contribution to coronary artery disease remains a challenge. Just as genetic analysis depends ...
AP Biology - TeacherWeb
AP Biology - TeacherWeb

... ƒ Mendel worked with a simple system peas are genetically simple most traits are controlled by a single gene ‹ each gene has only 2 alleles, 1 of which is completely dominant to the other ...
B/B a/a - kcpe-kcse
B/B a/a - kcpe-kcse

... 1. Genes can have alternate versions called alleles. 2. Each offspring inherits two alleles, one from each parent. 3. If the two alleles differ, the dominant allele is expressed. The recessive allele remains hidden unless the dominant allele is absent. 4. The two alleles for each trait separate duri ...
The Genetics of Cognitive Abilities and Disabilities
The Genetics of Cognitive Abilities and Disabilities

... of about 50 percent for both verbal and spatial ability. In contrast, the scores of increases from about 0.1 at age three to spatial abilities. adopted children do not resemble those about 0.3 at age 16. A similar pattern is In our own Colorado Adoption Proj- of their adoptive parents at all. These ...
Mining Gene Expression Data Using PCA Based Clustering
Mining Gene Expression Data Using PCA Based Clustering

... addition, the results illustrate that the quality of clustering will be better in the proposed algorithm. This can provide more accurate results and insight into molecular process, morphological characteristics and gene control functions. Figures 2 and 3 depict a large contiguous group of genes shar ...
Transcription – Gene regulation
Transcription – Gene regulation

... conserved regions in the sequences. E.coli promoters are found to contain 3 conserved sequence features - a region approximately 6 bp long with consensus TATAAT at position -10 - a region approximately 6 bp long with consensus TTGACA at position -35 - a distance between these 2 regions of ca. 17 bp ...
Dominant Gene
Dominant Gene

... 1. Inherited characteristics are controlled by genes. Genes happen in pairs. During fertilization 2 genes come together to form a pair. 2. Principle of Dominance one gene masks the effect of another. The gene for round seed coats masks the effect of the gene for wrinkled seed coats. Round is dominan ...
Transcriptional Repression of Hox Genes by C. elegans HP1/HPL
Transcriptional Repression of Hox Genes by C. elegans HP1/HPL

... Here, we investigate the role of HP1 and H1 in development using the nematode C. elegans as a model system. We focus on the underlying molecular mechanisms of gene co-regulation by H1 and HP1. We show that the loss of both HP1 and H1 alters the expression of a small subset of genes. C. elegans HP1 a ...
Gabriele Marras
Gabriele Marras

... The main objective of this step was to obtain automatically, from a list of SNPs, all related genes and associated ontologies and metabolic pathways. Pathway analysis results The results of the pathway analysis show a large number of pathways; however many have high p-values (non significan ...
Wnt Genes Review - Stanford University
Wnt Genes Review - Stanford University

... Writ coding sequences have been isolated from the widely studied species listed in Table 1, as well as from zebrafish (Molven et al., 1991), several other vertebrates (including birds, reptiles, and jawless fishes), sea urchins, starfish (Sidow, 1992), Axolotl (Busseet al., 1990), and leech (Kostrik ...
Reconstruction of a Functional Human Gene Network, with an
Reconstruction of a Functional Human Gene Network, with an

See a Sample
See a Sample

... © 2005 Prentice Hall Inc. / A Pearson Education Company / Upper Saddle River, New Jersey 07458 ...
- Purugganan Lab
- Purugganan Lab

... following section, we will summarize some of these notable examples in which specific genes responsible for putatively or established adaptive phenotypic variation have been identified. These studies represent the application of the techniques described in the previous sections. Adaptive trait locus ...
benfey_ch10
benfey_ch10

... © 2005 Prentice Hall Inc. / A Pearson Education Company / Upper Saddle River, New Jersey 07458 ...
Kevin Ann Hunt Term paper
Kevin Ann Hunt Term paper

... In this study, the data determined a primary role for Grhl2 in the Axd phenotype. Grhl2 is located within the 1.1 Mb critical region, up-regulation is associated with increase in PNP closure time in Axd/Axd mice, over-expression of Grhl2 is visible in the surface ectoderm and hindgut tissues (tissue ...
View PDF
View PDF

... PWS–AS region was accompanied by (or perhaps caused by) the fusion of SNRPN and UBE3A and the evolution of the ICR. Concurrently, SNURF and the snoRNAs were acquired, and MKRN3, MAGEL2 and NDN were retroposed into this domain. This occurred after the divergence of eutherians and marsupials 180 MYA, ...
Time-shift and inverse clustering of expression data finds new
Time-shift and inverse clustering of expression data finds new

... At the end of this procedure, one obtains a match score and a relationship, i.e., "simultaneous," "time-delayed," "inverted," or "inverted time-delayed". Obviously, for the gene pairs with a very low match score, even though they are also assigned a relationship, we can classify them as “unmatched”. ...
Eye Development
Eye Development

Lab_36 - PCC - Portland Community College
Lab_36 - PCC - Portland Community College

... Ss = sickle-cell trait (both aberrant and normal Hb is made) ss = sickle-cell anemia (only aberrant Hb is made) ...
A programme for the construction of a lambda phage
A programme for the construction of a lambda phage

... time required for RNA polymerase to reach the gene from its promoter /?R , 7000 base-pairs away. The product of Q activates transcription initiated at P'R to traverse the late genes, whose products are responsible for DNA encapsidation and cell lysis. The Q protein acts as an antiterminator, employi ...
Lab_36_old - PCC - Portland Community College
Lab_36_old - PCC - Portland Community College

... Ss = sickle-cell trait (both aberrant and normal Hb is made) ss = sickle-cell anemia (only aberrant Hb is made) ...
Floral organ identity genes in the orchid
Floral organ identity genes in the orchid

... (RACE) method was employed to further isolate full-length cDNAs of AP2, AP3, PISTILLATA (PI), AGAMOUS (AG) and SEPALLATA (SEP) orthologs. These orthologs were named DcOAP2 (D. crumenatum AP2-like gene), DcOAP3A, DcOAP3B, DcOPI, DcOAG1, DcOAG2 and DcOSEP1 (GenBank accession numbers DQ119837, DQ119838 ...
Is targeted modification of cytokinin regulatory gene activity in Rapid
Is targeted modification of cytokinin regulatory gene activity in Rapid

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Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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