Text S1.
... [2] or the 1000 Genomes Project [3]). Putatively functional genotypes are only counted if they occur in genes annotated as being associated with the phenotype. Second layer. These nodes represent genes, split into those annotated as high penetrance GH or low penetrance GL. Their values depend on lin ...
... [2] or the 1000 Genomes Project [3]). Putatively functional genotypes are only counted if they occur in genes annotated as being associated with the phenotype. Second layer. These nodes represent genes, split into those annotated as high penetrance GH or low penetrance GL. Their values depend on lin ...
Recall Questions
... substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier for a Robertsonian transloca ...
... substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier for a Robertsonian transloca ...
Expert Reviews in Molecular Medicine Androgenetic alopecia
... receptor, a member of the steroid-thyroid hormone nuclear receptor superfamily. The structure of the androgen receptor includes a ligand-binding domain and a DNA-binding domain. Both testosterone and DHT can bind to the ligand domain, which activates the DNAbinding domain. The receptor–ligand comple ...
... receptor, a member of the steroid-thyroid hormone nuclear receptor superfamily. The structure of the androgen receptor includes a ligand-binding domain and a DNA-binding domain. Both testosterone and DHT can bind to the ligand domain, which activates the DNAbinding domain. The receptor–ligand comple ...
CONSERVATION AND DIVERGENCE IN MOLECULAR
... Regulation of Dpp signaling is also mediated by the tolloid gene. tolloid embryos have a ventralized cuticle phenotype, and are missing the most dorsal structures (amnioserosa) as well as some dorsal epidermis (74, 156). tolloid is expressed dorsally, encodes a metalloprotease, and has been shown ge ...
... Regulation of Dpp signaling is also mediated by the tolloid gene. tolloid embryos have a ventralized cuticle phenotype, and are missing the most dorsal structures (amnioserosa) as well as some dorsal epidermis (74, 156). tolloid is expressed dorsally, encodes a metalloprotease, and has been shown ge ...
View PDF - OSU Biochemistry and Molecular Biology
... always result in such dramatic phenotypes—they can also cause very subtle defects, as frequently observed in organisms with multiple Hox clusters (e.g. vertebrates) due to the overlapping expression and functional redundancy of paralogous Hox genes of different clusters.(11) In these cases, major mo ...
... always result in such dramatic phenotypes—they can also cause very subtle defects, as frequently observed in organisms with multiple Hox clusters (e.g. vertebrates) due to the overlapping expression and functional redundancy of paralogous Hox genes of different clusters.(11) In these cases, major mo ...
An Agony in Five Fits (R
... makes fascinating reading today, and I cannot resist quoting him at some length: My dear Darwin, — I have been so repeatedly struck by the utter inability of numbers of intelligent persons to see clearly, or at all, the selfacting and necessary effects of Natural Selection, that I am led to conclude ...
... makes fascinating reading today, and I cannot resist quoting him at some length: My dear Darwin, — I have been so repeatedly struck by the utter inability of numbers of intelligent persons to see clearly, or at all, the selfacting and necessary effects of Natural Selection, that I am led to conclude ...
Feline Genetics: a Combinatorial Approach
... sharply instead of gradually: their effect shows up completely or not at all, according to which variant (allele) of the gene is considered. So, rather than DNA proteins, we shall have the combinatorics of symbols, standing for genes. Please be warned that the mathematical models are aimed to explai ...
... sharply instead of gradually: their effect shows up completely or not at all, according to which variant (allele) of the gene is considered. So, rather than DNA proteins, we shall have the combinatorics of symbols, standing for genes. Please be warned that the mathematical models are aimed to explai ...
Systematic Studies on the Family Cucurbitaceae
... The only gene reported to influence the mechanical characteristics of the rind (toughness and flexibility) was the t gene for the thin, tender rind, bursting when cut, from 'California Klondike' (35), renamed e for explosive rind by Poole (1944). So far, no study has described the inheritance of rin ...
... The only gene reported to influence the mechanical characteristics of the rind (toughness and flexibility) was the t gene for the thin, tender rind, bursting when cut, from 'California Klondike' (35), renamed e for explosive rind by Poole (1944). So far, no study has described the inheritance of rin ...
Package ‘siggenes’ October 14, 2014
... summarizes how many observations in this group show which level at which variable. These matrices can be generated using the function rowTables from the package scrime. For details on how to specify this list, see the examples section on this man page, and the help for rowChisqMultiClass in the pack ...
... summarizes how many observations in this group show which level at which variable. These matrices can be generated using the function rowTables from the package scrime. For details on how to specify this list, see the examples section on this man page, and the help for rowChisqMultiClass in the pack ...
Homeotic genes regulate the spatial expression
... primordium, where the RNA is seen, and then some of the protein appears to move into adjacent cells (van den Heuvel et al. 1989). Studies of mosaic adult flies in which some of the cells lack all wg function while other surrounding cells have one functional copy of the gene have shown that mutant ce ...
... primordium, where the RNA is seen, and then some of the protein appears to move into adjacent cells (van den Heuvel et al. 1989). Studies of mosaic adult flies in which some of the cells lack all wg function while other surrounding cells have one functional copy of the gene have shown that mutant ce ...
Gene expression analysis
... Ulf Leser and Karin Zimmermann Ulf Leser: Bioinformatics, Wintersemester 2010/2011 ...
... Ulf Leser and Karin Zimmermann Ulf Leser: Bioinformatics, Wintersemester 2010/2011 ...
Regulation of Ovule Development
... 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell proliferation in the marginal tissues of the pistil, specifically ...
... 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell proliferation in the marginal tissues of the pistil, specifically ...
Global transcriptional control by glucose and
... Clostridium difficile binary toxin (CDT), which is produced by 35% of C. difficile strains, has been recently shown to play a role in adherence to the host intestinal epithelial cells (11). Other factors, such as the adhesin Cwp66, the flagellum, the fibronectin-binding protein FbpA and the surface laye ...
... Clostridium difficile binary toxin (CDT), which is produced by 35% of C. difficile strains, has been recently shown to play a role in adherence to the host intestinal epithelial cells (11). Other factors, such as the adhesin Cwp66, the flagellum, the fibronectin-binding protein FbpA and the surface laye ...
Inhibition of respiration by Nitric Oxide induces a
... • Green: repressed • Black: no change • Genes organized ...
... • Green: repressed • Black: no change • Genes organized ...
understanding heredity
... of his research with rabbits, guinea pigs, monkeys, and even frogs and yet can apply his results on the human level. Finally, there are phenomena in nature which are of such a generalized kind that they are the same in all animals and even in all plants. Man, fish, insects, and plants seem to breath ...
... of his research with rabbits, guinea pigs, monkeys, and even frogs and yet can apply his results on the human level. Finally, there are phenomena in nature which are of such a generalized kind that they are the same in all animals and even in all plants. Man, fish, insects, and plants seem to breath ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
... textbooks incorrectly refer to the plastid of the glaucocystophyte Cyanophora paradoxa as an unreduced cyanobacterium. In fact, the C. paradoxa plastid genome shows the same reduction as other plastids when compared to free-living cyanobacteria (it is 136 kb and contains 191 genes; Stirewalt et al. ...
... textbooks incorrectly refer to the plastid of the glaucocystophyte Cyanophora paradoxa as an unreduced cyanobacterium. In fact, the C. paradoxa plastid genome shows the same reduction as other plastids when compared to free-living cyanobacteria (it is 136 kb and contains 191 genes; Stirewalt et al. ...
Developing a Bioassay for Triclosan Toxicity Abstract
... there was an increase in the gene expression of two genes : ndr2 and pkd2 in TCS treated embryos compared to control embryos, with gli2a being unaffected. However, the control genes did not behave as expected. As a result, the data could not be normalized and validated. Though the reference genes we ...
... there was an increase in the gene expression of two genes : ndr2 and pkd2 in TCS treated embryos compared to control embryos, with gli2a being unaffected. However, the control genes did not behave as expected. As a result, the data could not be normalized and validated. Though the reference genes we ...
Exceptionally high levels of recombination
... markers to physical distance (Mb) in 250- and 125-kb nonoverlapping windows. Estimates of genetic distance were integrated from 1500 new genetic markers and two independent genetic maps, one based on 1100 AFLP and RAPD markers (of which 300 were cloned and anchored to the sequence), and a microsatel ...
... markers to physical distance (Mb) in 250- and 125-kb nonoverlapping windows. Estimates of genetic distance were integrated from 1500 new genetic markers and two independent genetic maps, one based on 1100 AFLP and RAPD markers (of which 300 were cloned and anchored to the sequence), and a microsatel ...
Parasitism and Mutualism in Wolbachia: What the
... Alignments of individual and concatenated genes both with and without outgroups were screened for significant levels of recombination using the pairwise homoplasy index (PHI) or PHItest (Bruen et al. 2006) implemented in SplitsTree4 under default conditions (Huson and Bryant 2006). As a positive con ...
... Alignments of individual and concatenated genes both with and without outgroups were screened for significant levels of recombination using the pairwise homoplasy index (PHI) or PHItest (Bruen et al. 2006) implemented in SplitsTree4 under default conditions (Huson and Bryant 2006). As a positive con ...
Mendel and modern genetics: the legacy for today
... establishing a generalized theory of heredity as was assumed by his early-20th century followers. These re-interpretations of Mendel also argue that nowhere does he explicitly state that the germ cells contain particles that determine the character of a trait. Mendel’s symbols (e.g. T,t and A,a), th ...
... establishing a generalized theory of heredity as was assumed by his early-20th century followers. These re-interpretations of Mendel also argue that nowhere does he explicitly state that the germ cells contain particles that determine the character of a trait. Mendel’s symbols (e.g. T,t and A,a), th ...
Feline Genetics: a Combinatorial Approach - MTMK-ICF
... sharply instead of gradually: their effect shows up completely or not at all, according to which variant (allele) of the gene is considered. So, rather than DNA proteins, we shall have the combinatorics of symbols, standing for genes. Please be warned that the mathematical models are aimed to explai ...
... sharply instead of gradually: their effect shows up completely or not at all, according to which variant (allele) of the gene is considered. So, rather than DNA proteins, we shall have the combinatorics of symbols, standing for genes. Please be warned that the mathematical models are aimed to explai ...
Mendel and modern genetics: the legacy for today
... establishing a generalized theory of heredity as was assumed by his early-20th century followers. These re-interpretations of Mendel also argue that nowhere does he explicitly state that the germ cells contain particles that determine the character of a trait. Mendel’s symbols (e.g. T,t and A,a), th ...
... establishing a generalized theory of heredity as was assumed by his early-20th century followers. These re-interpretations of Mendel also argue that nowhere does he explicitly state that the germ cells contain particles that determine the character of a trait. Mendel’s symbols (e.g. T,t and A,a), th ...