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Basic Bioinformatics - NIU Department of Biological Sciences
Basic Bioinformatics - NIU Department of Biological Sciences

... Mostly genes are named with the function of their protein. – at some point, some related genes had their function determined through lab work: by examining the effects of mutations in the gene, by isolating and studying the protein produced by the gene, etc. – Enzymes (end in –ase), transport across ...
Basic Bioinformatics
Basic Bioinformatics

... Mostly genes are named with the function of their protein. – at some point, some related genes had their function determined through lab work: by examining the effects of mutations in the gene, by isolating and studying the protein produced by the gene, etc. – Enzymes (end in –ase), transport across ...
hinv1
hinv1

... clones for functional assays ① (Unexpected) relationship with other phenotypes suggesting (i) shared pathways and/or (ii) shared lifestyle/ env factors ② Selection of candidate genes/ markers ...
Lec-Functional Annotation and Functional Enrichment2010
Lec-Functional Annotation and Functional Enrichment2010

... takes place. Molecular functions generally correspond to activities that can be performed by individual gene products, but some activities are performed by assembled complexes of gene products. • Examples of broad functional terms are catalytic activity, transporter activity, or binding; examples of ...
Unit 4 – Genetics Heredity Test Study Guide Chapter 13
Unit 4 – Genetics Heredity Test Study Guide Chapter 13

... 2. Looking at progeny (offspring), how might one guess that two genes are linked? 3. When studying linked genes, how do you explain the appearance of progeny that do not share either parental phenotype? 4. How can recombination data be used to map genetic loci? 5. Use the following recombination fre ...
Gene Transcription in Prokaryotes
Gene Transcription in Prokaryotes

... Gene Transcription in Prokaryotes • Operons: in prokaryotes, genes that encode protein participating in a common pathway are organized together. – This group of genes, arranged in tandem, is called an OPERON. ...
A detailed gene map of pig chromosome 4, where the first
A detailed gene map of pig chromosome 4, where the first

... task and there have not been many success stories presented yet. A recent compilation of genes identified from QTL studies summarized 29 genes so far; 28 those were identified in human/mouse/rat and only one in a livestock animal. Porcine chromosome 4 (SSC4) harbor QTLs affecting growth, carcass tra ...
Pi kur, 2004
Pi kur, 2004

Genetics 200A 2009 Prokaryotes Lecture 1 (Cox)
Genetics 200A 2009 Prokaryotes Lecture 1 (Cox)

... Results: Alan Campbell isolated 130 mutants: they grow in bacterial strain C600 (suII+) but not in wild-type bacterial strain such as 594 (su°). Do the mutations affect different functions/genes? This can be determined by doing pairwise co-infections with individual mutants. It is important that mo ...
“This is getting really old . . . ” The Genetics of Aging
“This is getting really old . . . ” The Genetics of Aging

... of damage to macromolecules, intracellular organelles, cells, tissues, organs. ...
II. Changes in chromosome number
II. Changes in chromosome number

... rearrangements are subject to natural selection and thus serve as instruments of evolution. a. Deletions remove DNA from a chromosome. Homozygosity for a large deletion is usually lethal, but even heterozygosity for a large deletion can create a deleterious genetic imbalance. Deletions may uncover r ...
Chapter 3 Genetics Study Guide
Chapter 3 Genetics Study Guide

... Codominance- neither allele is dominant or recessive: Also results in a third trait different from the parents ( think black rooster, white rooster= black and white rooster) Probability- The chances of an event occurring Allele- the different forms of a gene Genes- factors that control a trait Trait ...
Heredity and Genetics Vocabulary (Part 2) 1. Traits: A
Heredity and Genetics Vocabulary (Part 2) 1. Traits: A

... Genetics: The scientific study of heredity. Allele: A form of a gene for a specific trait. Offspring: The new organisms produced by one or two parent organisms. Punnett square: A chart used to show all the ways genes from two parents can combine and be passed to offspring; used to predict all genoty ...
Agaba et al - Centre for Genomic Research
Agaba et al - Centre for Genomic Research

... The analysis procedure itself could be reused or adapted for studying another species or another phenotypic trait for which QTL data are available. In the case of the bovine trypanotolerance study, the result can be quantified in terms of the reduction of an enormous set of potential targets for inv ...
A Hybrid Knowledge-Driver Approach to Clustering Gene
A Hybrid Knowledge-Driver Approach to Clustering Gene

... with the actual gene clustering process. Existing information about a genes molecular function, the biological process in which it takes part and the cellular component in which it resides is retrieved and encapsulated within the actual clustering process. Including the vast amounts of available li ...
Solutions 9
Solutions 9

... c) Suppose the new population consists of the six offspring individuals received by the crossover operations in the above question. Evaluate the fitness of the new population, showing all your workings. Has the overall fitness improved? Answer: ...
MADS Monsters: Controlling Floral Organ Identity
MADS Monsters: Controlling Floral Organ Identity

... homeotic proteins. For example, in Arabidopsis, heterodimers of the B-class proteins AP3 and PI would complex with heterodimers of class-A AP1 and class-E SEP proteins to specify petals in whorl 2 and with heterodimers of class-C AG and class-E SEP to specify stamens in whorl 3. In whorl 4, carpels ...
THE HUMAN GENOME PROJECT
THE HUMAN GENOME PROJECT

... •The human genome contains 3 billion nucleotide bases (A, C, T, and G). ...
Supplemental Figure Legends
Supplemental Figure Legends

Questions 15: Genetic Algorithms
Questions 15: Genetic Algorithms

... Answer: On each day, a solution is a combination of 3 cabin crews assigned to 5 airplanes. Thus, a chromosome of 3 genes could be used in this algorithm with each gene representing a crew on a certain plain. b) Suggest what could be the alphabet of this algorithm? What is its size? Answer: The alpha ...
Affymetrix Data analysis
Affymetrix Data analysis

... 7.1. The scatterplot is a visualization that is useful for assessing the variation (or reproducibility, depending on how you look at it) between chips. We can look at all probes, the perfect match probes only, the mismatch probes only, and of course also at the normalized, probe-set-summarized data. ...
Chromosome Theory Sex Chromosomes
Chromosome Theory Sex Chromosomes

... egg cell; no mitochondria come from the sperm during fertilization in plants, the chloroplasts are often inherited from the mother, although this is species dependent ...
Recent advances in bioinformatics and computational biology
Recent advances in bioinformatics and computational biology

... find the optimal alignment of a group of nucleotide or protein sequences is a combinatorial optimization problem. Metaheuristics are approaches that guide local heuristic search procedure to explore the solution space beyond local optimality. Examples of metaheuristics include genetic algorithm, sim ...
Hons Pharmaco DBs
Hons Pharmaco DBs

Basic Equine Genetics.indd
Basic Equine Genetics.indd

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Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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