On the Mutational Topology of the Bacterial Genome
... repeated sequences [insertion sequence (IS) elements, rRNA operons, and other smaller repeat sequences] could not be defined and thus were excluded from the data. To account for this complication, we eliminated all the gaps that included IS or rRNA operons (other repeated sequences are too small to b ...
... repeated sequences [insertion sequence (IS) elements, rRNA operons, and other smaller repeat sequences] could not be defined and thus were excluded from the data. To account for this complication, we eliminated all the gaps that included IS or rRNA operons (other repeated sequences are too small to b ...
it is not in our genes
... Although the reader might find it hard to believe, it is completely uncontroversial—an established and oft-repeated fact within the scientific literature— that, so far, genes identified by the HGP explain only 1–5% of the variance between groups for psychological traits of all kinds. This assertion ...
... Although the reader might find it hard to believe, it is completely uncontroversial—an established and oft-repeated fact within the scientific literature— that, so far, genes identified by the HGP explain only 1–5% of the variance between groups for psychological traits of all kinds. This assertion ...
Smchd1 regulates a subset of autosomal genes subject to
... total) were distributed between those with increased transcript levels (157 genes) and those with decreased levels (133 genes) in Smchd1MommeD1/MommeD1 compared with Smchd1+/+ embryos. The cell cycle related genes Ccng1 and Cdkn1a were high in the ranked list of significantly upregulated transcripts ...
... total) were distributed between those with increased transcript levels (157 genes) and those with decreased levels (133 genes) in Smchd1MommeD1/MommeD1 compared with Smchd1+/+ embryos. The cell cycle related genes Ccng1 and Cdkn1a were high in the ranked list of significantly upregulated transcripts ...
Statistical Analysis of Microarray Data
... Simple normalization of microarray data. The difference between the raw fluorescence is a meaningless number. Computing ratios allows immediate visualization of which genes are higher in the red channel than the green channel, but logarithmic transformation of this measure on the base 2 scale result ...
... Simple normalization of microarray data. The difference between the raw fluorescence is a meaningless number. Computing ratios allows immediate visualization of which genes are higher in the red channel than the green channel, but logarithmic transformation of this measure on the base 2 scale result ...
Apresentação do PowerPoint
... molecular biology of parasitic protozoa • 2 - To show you that most parasites present great genetic diversity • 3 -To discuss how the information generated in Parasite Genome Projects - that employ Reference Organisms - can be used to approach specific problems of parasite isolates ...
... molecular biology of parasitic protozoa • 2 - To show you that most parasites present great genetic diversity • 3 -To discuss how the information generated in Parasite Genome Projects - that employ Reference Organisms - can be used to approach specific problems of parasite isolates ...
Overexpression of miR165 Affects Apical
... miRNAs have been identified from a diverse group of species and, of them, many putative target genes have been predicted (Dugas and Bartel 2004, Kidner and Martienssen 2005a, Zhang et al. 2006). It has been shown that miRNAs are first transcribed by RNA polymerase II to produce pri-miRNAs, which are ...
... miRNAs have been identified from a diverse group of species and, of them, many putative target genes have been predicted (Dugas and Bartel 2004, Kidner and Martienssen 2005a, Zhang et al. 2006). It has been shown that miRNAs are first transcribed by RNA polymerase II to produce pri-miRNAs, which are ...
Clustering
... 2. Create a distance matrix for the distance between every two gene points in the N-dimensional space. 3. Genes with a small distance share the same expression characteristics and might be functionally related or similar. 4. Therefore, clustering “close” genes together reveals groups of functionally ...
... 2. Create a distance matrix for the distance between every two gene points in the N-dimensional space. 3. Genes with a small distance share the same expression characteristics and might be functionally related or similar. 4. Therefore, clustering “close” genes together reveals groups of functionally ...
1.5 - Biology Junction
... Some genes use proteins that speed transcription. Sometimes regulation occurs at the level of protein synthesis. ...
... Some genes use proteins that speed transcription. Sometimes regulation occurs at the level of protein synthesis. ...
Y chromosome
... Nettie Stevens was a talented cytogeneticist who discovered heteromorphic chromosome pair in insects. She was the first to propose that the X and Y -bearing sperm determined the sex of the zygote. ...
... Nettie Stevens was a talented cytogeneticist who discovered heteromorphic chromosome pair in insects. She was the first to propose that the X and Y -bearing sperm determined the sex of the zygote. ...
The mystery of the tallest giants is revealed
... The cause of this hyperproduction of growth hormone is situated in the pituitary gland, the part of the brain where a large range of hormones are produced. In most cases of gigantism or acromegaly, a pituitary adenoma is the cause of this hormonal imbalance. It is a benign tumor affecting this gland ...
... The cause of this hyperproduction of growth hormone is situated in the pituitary gland, the part of the brain where a large range of hormones are produced. In most cases of gigantism or acromegaly, a pituitary adenoma is the cause of this hormonal imbalance. It is a benign tumor affecting this gland ...
On the energy and material cost of gene duplication
... ribosomes, rendering them unavailable for expressing other genes at appropriate levels. Experimental approaches like these are powerful, because they can directly demonstrate the effects of gene expression on cell growth. However, they can detect the expression costs of only the most highly expresse ...
... ribosomes, rendering them unavailable for expressing other genes at appropriate levels. Experimental approaches like these are powerful, because they can directly demonstrate the effects of gene expression on cell growth. However, they can detect the expression costs of only the most highly expresse ...
Chromosomal Basis
... The Chromosomal Basis of Inheritance A. Relating Mendelian Inheritance to the Behavior of Chromosomes 1. Mendelian inheritance has its physical basis in the behavior of chromosomes during sexual life cycles. ...
... The Chromosomal Basis of Inheritance A. Relating Mendelian Inheritance to the Behavior of Chromosomes 1. Mendelian inheritance has its physical basis in the behavior of chromosomes during sexual life cycles. ...
Gene Section PAX5 (paired box gene 5) Atlas of Genetics and Cytogenetics
... DC, Dyomin V, Ohno H, Chaganti RS, Dalla-Favera R. The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene. ...
... DC, Dyomin V, Ohno H, Chaganti RS, Dalla-Favera R. The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene. ...
Incomplete lineage sorting and other `rogue` data fell the tree of life
... Finally, one of the most extensively investigated methodologies in recent years, and perhaps also the most theoretical and obfuscated, involves modelling the largely hypothetical coalescent process using a variety of statistical methodologies.10,29–31 It must be noted that these are ‘inference’ base ...
... Finally, one of the most extensively investigated methodologies in recent years, and perhaps also the most theoretical and obfuscated, involves modelling the largely hypothetical coalescent process using a variety of statistical methodologies.10,29–31 It must be noted that these are ‘inference’ base ...
Document
... • Mosaicism – two or more populations of cells with different genotypes within a single organism • most common forms rise from errors in the first few mitotic divisions of a fertilized zygote ...
... • Mosaicism – two or more populations of cells with different genotypes within a single organism • most common forms rise from errors in the first few mitotic divisions of a fertilized zygote ...
Document
... 7.1 Chromosomes and Phenotype • Female mammals have an XX genotype. – Expression of sex-linked genes is similar to autosomal genes in females. – X chromosome inactivation randomly “turns off” one X chromosome – ensures that females, like males, have one functional copy of the X chromosome in each b ...
... 7.1 Chromosomes and Phenotype • Female mammals have an XX genotype. – Expression of sex-linked genes is similar to autosomal genes in females. – X chromosome inactivation randomly “turns off” one X chromosome – ensures that females, like males, have one functional copy of the X chromosome in each b ...
Section J Analysis and Uses of Cloned DNA
... • Length of target sequences: Short target sequences amplify more easily, so often this distance is less than 500 bp, but, with optimization, PCR can amplify fragments over 10 kb in length. • Primer design: – The region to be amplified should be inspected for two sequences of about 20 nt with a ...
... • Length of target sequences: Short target sequences amplify more easily, so often this distance is less than 500 bp, but, with optimization, PCR can amplify fragments over 10 kb in length. • Primer design: – The region to be amplified should be inspected for two sequences of about 20 nt with a ...
Apresentação do PowerPoint
... Allen EAD., Gorham PR. 1981. Culture of planktonic cyanophytes on agar, In W. W. Carmichael (ed.), The water environment: algal toxins and health. Plenum Publishing. Corp., New York. p. 185-192. Hisbergues M, Christiansen G, Rouhiainen L, Sivonen K, Borner T. 2003. PCR-based identification of microc ...
... Allen EAD., Gorham PR. 1981. Culture of planktonic cyanophytes on agar, In W. W. Carmichael (ed.), The water environment: algal toxins and health. Plenum Publishing. Corp., New York. p. 185-192. Hisbergues M, Christiansen G, Rouhiainen L, Sivonen K, Borner T. 2003. PCR-based identification of microc ...
NIHMS88703-supplement-2
... A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our met ...
... A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our met ...
Topic 2.4 The Nature and Nurture of Brain Development
... embryo and appear to illustrate epigenesis. With development, these simple cells can become a complex set of tissue that the body needs (e.g., brain tissue, muscle). At birth, many traits are like stem cells as they represent an inherited potential that can be shaped by experience. II. ...
... embryo and appear to illustrate epigenesis. With development, these simple cells can become a complex set of tissue that the body needs (e.g., brain tissue, muscle). At birth, many traits are like stem cells as they represent an inherited potential that can be shaped by experience. II. ...