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Slide 1
Slide 1

... • Alleles can be represented using letters. – A dominant allele is expressed as a phenotype when at least one allele is dominant. – A recessive allele is expressed as a phenotype only when two copies are present. – Dominant alleles are represented by uppercase letters; recessive alleles by lowercas ...
Chapter 6 Meiosis and Mendel
Chapter 6 Meiosis and Mendel

... Many Genes May Interact to Produce One Trait Polygenic Traits  Traits produced by two or more genes are called Polygenic Traits. Ex: Human skin color and eye color are polygenic. ...
bio3studentexemplars_7jul06
bio3studentexemplars_7jul06

... homologous chromosomes can’t pair properly for meiosis. Achievement with Excellence This is only possible by a mutation occurring such as a block translocation of the X chromosome to another or by non-disjunction resulting in aneuploidy. The translocation affects the cat’s sex chromosomes and is lik ...
Document
Document

... changes (new uses of old ideas and methods) are at least as productive as structural changes (new ideas and new methods). Shortly, we will examine some potentially useful tools from evolutionary biology that may be of some use to livestock researchers. However, two important caveats are in order fir ...
Basic Sheep Genetics - UK College of Agriculture
Basic Sheep Genetics - UK College of Agriculture

... is also one quarter. A lamb with the genotype Ww may be produced in one of two ways. A lamb will be heterozygous white-wooled if the sperm carries the W gene and the egg carries the w gene (which, using the first probability rule, will occur ½ × ½ = ¼ of the time) or if the sperm carries the w gen ...
In Silico Mapping of Complex Disease
In Silico Mapping of Complex Disease

... on the carrier chromosomes. Depending on how close the two loci are, this will occur more or less frequently, and if the two loci are very close together, the haplotype a1 m1 may remain in the population a very long time. During this time the frequency of could increase well beyond its original 1/n, ...
Basic Concepts of Genetic Improvement
Basic Concepts of Genetic Improvement

... pair. This splitting of chromosome pairs causes a random transfer of each member into a forming gamete. When the egg and the sperm unite at fertilization, each carries only one member of each original chromosome Figure 3. Nonadditive gene action for one gene pair. pair. The joining of a particular e ...
Genetics and Sensorineural Hearing Loss (SNHL)
Genetics and Sensorineural Hearing Loss (SNHL)

... Deafness can also be caused by alterations in ‘dominant’ genes. In this situation an alteration in just one copy of the gene is enough to cause problems. The second, healthy, copy of the gene is unable to compensate. ...
LAB 10
LAB 10

... (MZ) twins arise from a single fertilized egg, which then begins to divide and splits into two embryos sometime during the first weeks of gestation. MZ twins account for about 28% of all twin births and are always the result of a random event that is not under genetic control. Therefore, MZ twins do ...
Mutations associated with QoI-resistance
Mutations associated with QoI-resistance

Document
Document

...  most people carry about 30 - 40 mutant alleles, but have only one allele for each trait, so it is covered up by the other normal dominant allele  family members have high probability of carrying the same mutant alleles  marrying a close relative increases the chance of an offspring getting 2 mut ...
AP Chapter 14-15 Study Guide: Chromosomes and Mendelian
AP Chapter 14-15 Study Guide: Chromosomes and Mendelian

... of the offspring from his first cross.) Much to his surprise, the F2 generation had plants in a ratio of 3 tall to 1 short. From this experiment and others using different traits, Mendel developed several conclusions 10. Mendel realized that the gene for short plants did get passed on, but it was hi ...
chapter 11 section 3 notes
chapter 11 section 3 notes

Flylab exercise - Wesleyan College Faculty
Flylab exercise - Wesleyan College Faculty

... The study of genetics is typically divided into three sub-areas, each dealing with a different aspect of the broad topic of genetics. Molecular genetics treats the study of the nuclear material itself, the DNA sequence of base pairs and the allied molecules that aid in DNA replication, transcription ...
Document
Document

... deciphering of the whole genome sequences of several organism has represented huge quantities of information. • New technologies such as DNA microarrays (but not only these!) allow the simultaneous study of hundreds, even thousands of genes, in a single experiment. ...
Congenital hyperinsulinism caused by a de novo mutation in the
Congenital hyperinsulinism caused by a de novo mutation in the

... mutation in a recessively-inherited disease (2). Rapid, high-throughput techniques for analysis of candidate genes have helped the care of patients with CHI. Genotyping guides further investigation of the patient and, because of the strong genotype-phenotype correlation, also the therapy (10,11). Th ...
Unit 4: Genetics & Heredity
Unit 4: Genetics & Heredity

...  Between anaphase I and telophase I when the homologous chromosomes separate & are packaged into different cells  Remember, Mendel didn’t even know DNA or genes existed! ...
Automating the Lee Model
Automating the Lee Model

... ME2 = computed peak time – measured peak time measured peak time – measured pinch time ...
Chapter 1 The Framework of Biology
Chapter 1 The Framework of Biology

... Mendelian inheritance governs some human traits. Some human traits are passed from parent to offspring through the dominant/recessive inheritance pattern. 10.4 More complex patterns of inheritance are an extension of Mendel's basic rules. Other types of inheritance patterns have been discovered sin ...
Understanding dominance/semi-dominance/co
Understanding dominance/semi-dominance/co

PUNNETT SQUARE PRACTICE
PUNNETT SQUARE PRACTICE

... Cystic fibrosis is a genetically transmitted condition in which the body produces excess mucus that clogs lungs and intestines. Persons who are heterozygous (Ff) for cystic fibrosis are carriers. Persons who are homozygous recessive (ff) have the disease. If a person who does not have the disease an ...
answers to exam 2011 - Learning on the Loop
answers to exam 2011 - Learning on the Loop

... trait within a population. Explanation of role of meiosis: Meiosis produces gametes with half the number of chromosomes. This means that pairs of alleles are separated at meiosis. At fertilisation, which sperm fertilise which egg is due to chance and this results in new combinations of alleles. The ...
Japanese Journal of Ophthalmology Vol.47 No.3
Japanese Journal of Ophthalmology Vol.47 No.3

... members. Fifty healthy individuals of Vietnamese origin served as controls. Leukocytes were pelleted, and transferred to Japan for molecular analysis. Genomic DNA was extracted from the leukocytes by standard procedures. Exons 4 and 12 of the TGFBI gene were amplified by polymerase chain reaction (P ...
name - cloudfront.net
name - cloudfront.net

... CA State Standards Covered This Week: ...
Part 1B Population and Community Dynamics - Science
Part 1B Population and Community Dynamics - Science

... Part 1. Genetic Diversity in Populations II) The Hardy-Weinberg Principle Sample Problem 2: Wing Length in Fruit Flies  A single pair of alleles codes for one of the genes that controls wing length in fruit flies (Drosophila melanogaster). The long wing allele (L) is dominant to the short wing alle ...
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Epistasis



Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.
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