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Entering the second century of maize quantitative genetics
... a detectable fitness effect implies that a large number of genes are not only involved in fitness but have segregating alleles with significant effects. Second, though the allelic distribution within genes is not completely proven, it appears to follow a ‘common gene, rare variant’ distribution wher ...
... a detectable fitness effect implies that a large number of genes are not only involved in fitness but have segregating alleles with significant effects. Second, though the allelic distribution within genes is not completely proven, it appears to follow a ‘common gene, rare variant’ distribution wher ...
SARS Outbreaks in Ontario, Hong Kong and Singapore: the role of
... fraction r are nonparental (or recombinant) gametes. A particular gamete, say AB, has a proportion (1-r) in generation t+1 produced without recombination. The frequency with which this gamete is produced in this way is (1-r)pAB(t). ...
... fraction r are nonparental (or recombinant) gametes. A particular gamete, say AB, has a proportion (1-r) in generation t+1 produced without recombination. The frequency with which this gamete is produced in this way is (1-r)pAB(t). ...
2n gametes in the potato: essential ingredients for breeding and
... Mutations causing 2n gamete formation may affect chromosome pairing, centromere division, spindle formation or cytokinesis during micro- and mega-sporogenesis. The first meiotic mutants in Solanum were discovered by Hanneman and Peloquin (1969). The unusually high seed set obtained from 4x×2x crosse ...
... Mutations causing 2n gamete formation may affect chromosome pairing, centromere division, spindle formation or cytokinesis during micro- and mega-sporogenesis. The first meiotic mutants in Solanum were discovered by Hanneman and Peloquin (1969). The unusually high seed set obtained from 4x×2x crosse ...
The geography of introgression in a patchy
... patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables (producing Genetic-Environment Association or GEA), genetic differentiation at neutral loci unlinked to any selected locus ...
... patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables (producing Genetic-Environment Association or GEA), genetic differentiation at neutral loci unlinked to any selected locus ...
Endoplasmic Reticulum Protein Quality Control Failure in Myelin
... glycans addition to asparagine residues (N-glycosylation) and protein oligomerization (Hebert and Molinari, 2007; Braakman and Hebert, 2013). Fundamental ERQC factors are the lectin chaperones calnexin (CNX) and calreticulin (CRT), which assist the folding of ER-synthesized glycoproteins (Figure 1; ...
... glycans addition to asparagine residues (N-glycosylation) and protein oligomerization (Hebert and Molinari, 2007; Braakman and Hebert, 2013). Fundamental ERQC factors are the lectin chaperones calnexin (CNX) and calreticulin (CRT), which assist the folding of ER-synthesized glycoproteins (Figure 1; ...
The geography of introgression in a patchy environment and the
... patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables (producing Genetic-Environment Association or GEA), genetic differentiation at neutral loci unlinked to any selected locus ...
... patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure of selected traits/loci tends to coincide with habitat variables (producing Genetic-Environment Association or GEA), genetic differentiation at neutral loci unlinked to any selected locus ...
Etude Annotation
... score (525) than the GeneMark start at position 215 (420). The start at position 83 is yields the longest possible gene as well. Gap/Overlap: Since it is gene 1, we can omit determining the gap ...
... score (525) than the GeneMark start at position 215 (420). The start at position 83 is yields the longest possible gene as well. Gap/Overlap: Since it is gene 1, we can omit determining the gap ...
video slide
... The Law of Independent Assortment • Mendel derived the law of segregation by following a single character • The F1 offspring produced in this cross were ...
... The Law of Independent Assortment • Mendel derived the law of segregation by following a single character • The F1 offspring produced in this cross were ...
8. Principles of Genetics and Cytogenetics
... Historical background of genetics, theories and hypothesis. Physical basis of heredity, cell reproduction, mitosis, meiosis and its significance. Gametogenesis and syngamy in plants. Mendelian genetics–Mendel’s principles of heredity, deviation from Mendelian inheritance, pleiotropy, threshold chara ...
... Historical background of genetics, theories and hypothesis. Physical basis of heredity, cell reproduction, mitosis, meiosis and its significance. Gametogenesis and syngamy in plants. Mendelian genetics–Mendel’s principles of heredity, deviation from Mendelian inheritance, pleiotropy, threshold chara ...
Genetic Allee effects and their interaction with ecological
... that population growth rate is affected and not just one fitness component. But since this study is only concerned with demographic Allee effects, we will simply refer to them as Allee effects in the following. There are two types of Allee effect with qualitatively different population dynamics: wea ...
... that population growth rate is affected and not just one fitness component. But since this study is only concerned with demographic Allee effects, we will simply refer to them as Allee effects in the following. There are two types of Allee effect with qualitatively different population dynamics: wea ...
Sex-specific Trans-regulatory Variation on the Drosophila melanogaster X Chromosome
... genetic variation at mutation-selection-drift balance [21]. However, more recent theory predicts that sexual dimorphism may develop more easily on the autosomes [22]. A further possibility that may affect levels of standing genetic variation on the X chromosome is the way in which dosage compensatio ...
... genetic variation at mutation-selection-drift balance [21]. However, more recent theory predicts that sexual dimorphism may develop more easily on the autosomes [22]. A further possibility that may affect levels of standing genetic variation on the X chromosome is the way in which dosage compensatio ...
Genomic analysis of clinical samples with serologic ABO blood
... blood group locus established.6 However, for many of the variant phenotypes of the ABO system our knowledge of the molecular basis for altered antigen expression is sparse. In 1993, molecular alterations at the ABO locus in individuals with inherited subgroup phenotypes were reported.7-10 Only one o ...
... blood group locus established.6 However, for many of the variant phenotypes of the ABO system our knowledge of the molecular basis for altered antigen expression is sparse. In 1993, molecular alterations at the ABO locus in individuals with inherited subgroup phenotypes were reported.7-10 Only one o ...
Baker, B. S., Hoff, G., Kaufman, T. C., Wolfner, M. W., and Hazelrigg, T. (1991). A cytopgenetic analysis of the doublesex locus and its flanking regions. Genetics 127: 125-138.
... affects female sexual differentiation, but only weakly affects male sexual differentiation. T h e interactions of ~ s x " ~ ~with ' * mutations in other genes affecting sexual differentiation are described. These results are discussed in terms of the recent molecular findings that the dsx locus enco ...
... affects female sexual differentiation, but only weakly affects male sexual differentiation. T h e interactions of ~ s x " ~ ~with ' * mutations in other genes affecting sexual differentiation are described. These results are discussed in terms of the recent molecular findings that the dsx locus enco ...
Two Different Functions of Connexin43 Confer
... first appear in embryo (14 –16). On the other hand there are several zebrafish bone growth mutants, in which bone development looks almost normal at early stages, but mutant phenotypes appear at late stages (type 2) (17–19). In this study, we focused on the stoepsel (stp) mutant fish (20) to study b ...
... first appear in embryo (14 –16). On the other hand there are several zebrafish bone growth mutants, in which bone development looks almost normal at early stages, but mutant phenotypes appear at late stages (type 2) (17–19). In this study, we focused on the stoepsel (stp) mutant fish (20) to study b ...
Document
... Mayr, E. 1970. Populations, Species, and Evolution: An Abridgement to “Animal Species and Evolution”. Harvard University Press. Orr, H. and Turelli, M. 2001. The evolution of postzygotic isolation: Accumulating Dobzhansky-Muller incompatibilities. Evolution ...
... Mayr, E. 1970. Populations, Species, and Evolution: An Abridgement to “Animal Species and Evolution”. Harvard University Press. Orr, H. and Turelli, M. 2001. The evolution of postzygotic isolation: Accumulating Dobzhansky-Muller incompatibilities. Evolution ...
genetics - Krishikosh
... -;eneticists who lectured in this series. For each of their lectures I have provided a chapter containing a ist of readings, a set of notes, and questions for discussion. At intervals a number of tests also are in~luded, each covering the material in a group of chapters. While these contents could f ...
... -;eneticists who lectured in this series. For each of their lectures I have provided a chapter containing a ist of readings, a set of notes, and questions for discussion. At intervals a number of tests also are in~luded, each covering the material in a group of chapters. While these contents could f ...
Interactions Between Genes Controlling Pathogenicity in the Flax
... was not used in any other crosses. The dikaryotic aeciospores arising from successful crosses were inoculated onto Hoshangabad plants to obtain sufficient urediospores to test on the full set of differential cultivars: the urediospores derived from one pustule of aeciospores constituted a single rus ...
... was not used in any other crosses. The dikaryotic aeciospores arising from successful crosses were inoculated onto Hoshangabad plants to obtain sufficient urediospores to test on the full set of differential cultivars: the urediospores derived from one pustule of aeciospores constituted a single rus ...
1 The Empirical Non-Equivalence of Genic and Genotypic Models of
... But in more realistic models it is highly unlikely that the long-term predictions will be the same, and so the point we are making becomes even more damning of genic selectionism when we move to models that more closely mirror reality. For instance, Nijhout (2003 and forthcoming) and Rice (1998, 20 ...
... But in more realistic models it is highly unlikely that the long-term predictions will be the same, and so the point we are making becomes even more damning of genic selectionism when we move to models that more closely mirror reality. For instance, Nijhout (2003 and forthcoming) and Rice (1998, 20 ...
Aggregate, composed, and evolved systems
... assumptions made about the structure of groups in models of group selection. The models started by focusing on genes and individual organisms but in the process made standard simplifying assumptions appropriate for some questions at those levels, but inappropriate for almost any questions about high ...
... assumptions made about the structure of groups in models of group selection. The models started by focusing on genes and individual organisms but in the process made standard simplifying assumptions appropriate for some questions at those levels, but inappropriate for almost any questions about high ...
1 Surrogate Genetics and Metabolic Profiling for Characterization of
... transformed into a cys4 yeast strain lacking the CBS ortholog CYS4. Centromere-based vectors were used to reduce copy-number variation. Eighty-one alleles derived from patients with homocystinuria plus three additional variants found in public databases were assayed. This collection of 84 missense m ...
... transformed into a cys4 yeast strain lacking the CBS ortholog CYS4. Centromere-based vectors were used to reduce copy-number variation. Eighty-one alleles derived from patients with homocystinuria plus three additional variants found in public databases were assayed. This collection of 84 missense m ...
Inferring Host Gene Subnetworks Involved in Viral
... explains or accounts for the viral phenotype observed when each hit is suppressed. Because the background network and experimental observations are incomplete, many different subnetworks may be inferred for the same set of hits. To account for this, our method infers an ensemble of subnetworks, each ...
... explains or accounts for the viral phenotype observed when each hit is suppressed. Because the background network and experimental observations are incomplete, many different subnetworks may be inferred for the same set of hits. To account for this, our method infers an ensemble of subnetworks, each ...
Stanford Encyclopedia of Philosophy
... variation in height of organisms could result from the contribution of several alleles at a locus where each allele contributes more height to the organism. For example, allele A could contribute .5 units to an organism's height, allele a another .5 units and so on. A contrast with additive genetic ...
... variation in height of organisms could result from the contribution of several alleles at a locus where each allele contributes more height to the organism. For example, allele A could contribute .5 units to an organism's height, allele a another .5 units and so on. A contrast with additive genetic ...
Epistasis
![](https://commons.wikimedia.org/wiki/Special:FilePath/Epistatic_hair.png?width=300)
Epistasis is a phenomenon that consists of the effect of one gene being dependent on the presence of one or more 'modifier genes' (genetic background). Similarly, epistatic mutations have different effects in combination than individually. It was originally a concept from genetics but is now used in biochemistry, population genetics, computational biology and evolutionary biology. It arises due to interactions, either between genes, or within them leading to non-additive effects. Epistasis has a large influence on the shape of evolutionary landscapes which leads to profound consequences for evolution and evolvability of traits.