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... Wang et al. and Clark et al. controlled for the reduction in neutral polymorphisms being due simply to reduced mutation rate by using a close relative (teosinte) as a control. The process of domestication itself is expected to reduce variation genome-wide because of the population bottleneck that i ...
Chapter 10
Chapter 10

... hedgehog, shrew, opposum, horse, elephant, pangolin, sloth, llama, and dolphin. Also sequenced are the genomes of many species of fruit flies, worms, and fungi, hundreds of bacteria, mitochondria, and chloroplasts, and thousands of viruses. Together these genomes represent a colossal amount of seque ...
Power Point Presentation
Power Point Presentation

... • Suggests that eukaryotes and archaea are more closely related to each other than to bacteria • Based largely on rRNA genes (evolved slowly) • There have been substantial interchanges of genes between organisms in different domains • Horizontal gene transfer is the movement of genes from one genome ...
Bcmb625-XistPaper-26apr07clp
Bcmb625-XistPaper-26apr07clp

... - Is fluorescence an accurate enough measure of transcriptional state? - What about the converse experiment express just the A-repeat region… - Experiments using truncations of the delta-A construct…. - Does the Xist domain co-localize with the nuclear structure components? - What is the nature of ...
Silene sex chromosome genetic map, p. 1 Expansion of
Silene sex chromosome genetic map, p. 1 Expansion of

... and complete sex-linkage, based on population genetic evidence. Linkage groups were inferred using the JoinMap software version 4.0 (van Ooijen 2006) with a minimum LOD (logarithm of odds) score of 3. JoinMap searches for the best fitting order of markers by a trial and error procedure. The map for ...
Ribosome profiling reveals post-transcriptional buffering of divergent
Ribosome profiling reveals post-transcriptional buffering of divergent

... mRNA fragments (RPFs). RPFs were then purified and used to generate strand-specific libraries for Illumina high-throughput sequencing (Ingolia et al. 2011). Strand-specific polyA-positive mRNA-seq libraries were made in parallel. Together, this approach measures both ribosome occupancy (RPF) and mRN ...
ucscDatabase
ucscDatabase

... float perCpg; "Percentage of island that is CpG" ...
TTEST – Between subjects
TTEST – Between subjects

... the distribution of the test statistic. • The ability to dynamically alter the input parameters based on immediate visual feedback, even before completing the analysis, should make the data-mining ...
Bioinformatik - Chair of Computational Biology
Bioinformatik - Chair of Computational Biology

... stoichiometry of metabolic reactions and capacity constraints. For E.coli the in silico results are consistent with experimental data. FBA shows that in the E.coli metabolic network there are relatively few critical gene products in central metabolism. However, the the ability to adjust to different ...
The evolution of developmental gene networks
The evolution of developmental gene networks

... The insects are traditionally viewed as one of the four major monophyletic arthropod groups, the other three being crustaceans, myriapods and chelicerates (Brusca & Brusca 2003). However, recent molecular phylogenies suggest that crustaceans are paraphyletic with respect to the insects; i.e. insects ...
PDF file
PDF file

...  Caused by ascomycete Anisograma anomala  Native to eastern North America ...
PowerPoint Presentation - Folie 1
PowerPoint Presentation - Folie 1

... reduced state, most commonly as (hydrogen) sulfide. In the absence of an environmental supply of reduced sulfur moieties (e.g. a black smoker or another organism), organisms have to reduce the needed sulfur themselves. In many microorganisms this function is performed by a very common pathway for as ...
Unequal Crossing Over Locus by KIR Cutting Edge: Expansion of the
Unequal Crossing Over Locus by KIR Cutting Edge: Expansion of the

... the cluster. Additional information regarding gene order has been garnered from a sequence-specific priming (SSP) protocol in which forward and reverse PCR primers were designed from gene-specific segments near the 3⬘ end and 5⬘ end of each KIR gene, respectively (3), which we will refer to as “inte ...
Wide-spread polyploidizations during plant evolution Dicot
Wide-spread polyploidizations during plant evolution Dicot

... How genomic repatterning occurred? •NCF: nested chromosome fusion ...
Epigenetic memory in mammals
Epigenetic memory in mammals

... Epigenetic information is encrypted in genetic sequences, and includes DNA methylation, histone modifications and small RNA changes (Bonasio et al., 2010). Epigenetic memory is the ability to transfer epigenetic information from one generation to the next. Epigenetic information uses patterns of inhe ...
video slide - Biology Junction
video slide - Biology Junction

... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
Analysis of Drosophila Species Genome Size and Satellite DNA
Analysis of Drosophila Species Genome Size and Satellite DNA

... ABSTRACT The size of eukaryotic genomes can vary by several orders of magnitude, yet genome size does not correlate with the number of genes nor with the size or complexity of the organism. Although ‘‘whole’’-genome sequences, such as those now available for 12 Drosophila species, provide informatio ...
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File

Genome duplications and accelerated evolution of
Genome duplications and accelerated evolution of

... result of a lineage-specific duplication. This assumption was based on the fact that, at the time, no more than four representatives from each paralogous groups had been isolated from other divergent teleost lineages such as Medaka and the striped bass (Kurosawa et al., 1999; Pavell and Stellwag, 19 ...
video slide - Course
video slide - Course

... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
Genomic Consequences of Background Effects on scalloped Mutant
Genomic Consequences of Background Effects on scalloped Mutant

... homeotic phenotype (Gibson et al. 1999), while modifiers of an Egfr gain-of-function allele suggest that the architecture of this photoreceptor determination phenotype was more likely due to many alleles of small effects (Dworkin et al. 2003). We ask here whether microarrays are a fine enough tool t ...
Genetics Power Point
Genetics Power Point

... Segregation of alleles during meiosis: • When the F1 plants produce gametes (sex cells) and self-pollinate, the two alleles for the same gene separate from each other so that each gamete carries only one copy of each gene. • Remember, gametes are haploid. In the example, we use “T” to represent the ...
Document
Document

... The Reality of “Round and Wrinkled” – Two Alternative Traits of the Seed Shape Character ...
Extracellular matrix gene expression in the developing
Extracellular matrix gene expression in the developing

... consisting of concentric layers of smooth muscle cells (SMCs) between sheets of elastin (the elastic laminae); and the tunica adventitia, made up of myofibroblasts that produce mainly collagen fibers. Within the medial layer, the collagen and elastin fibers are arranged to form a ‘‘two-phase’’ syste ...
DNA Diversity in Sex-Linked and Autosomal Genes of the Plant
DNA Diversity in Sex-Linked and Autosomal Genes of the Plant

... Y-linked genes have become less and less functional. A further consequence of these processes is reduction of the effective population size of Y-linked genes, which should therefore have reduced neutral variability. In chromosome regions with no recombination, such as Y chromosomes, these effects on ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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